Target-Templated Construction of Functional Proteomimetics Using Photo-Foldamer Libraries.

Autor: Wéber E; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.; HUN-REN-SZTE Biomimetic Systems Research Group, Dóm tér 8, H-6720, Szeged, Hungary., Ábrányi-Balogh P; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Nagymihály B; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary., Menyhárd DK; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, H-1117, Budapest, Hungary.; HUN-REN-ELTE Protein Modeling Research Group, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Péczka N; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Gadanecz M; Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, H-1117, Budapest, Hungary.; Hevesy György PhD School of Chemistry, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Schlosser G; MTA-ELTE Lendület Ion Mobility Mass Spectrometry Research Group, Institute of Chemistry, Eötvös Loránd University, Egyetem tér 1-3, H-1053, Budapest, Hungary., Orgován Z; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Bogár F; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.; HUN-REN-SZTE Biomimetic Systems Research Group, Dóm tér 8, H-6720, Szeged, Hungary., Bajusz D; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Kecskeméti G; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary., Szabó Z; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary., Bartus É; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.; HUN-REN-SZTE Biomimetic Systems Research Group, Dóm tér 8, H-6720, Szeged, Hungary., Tököli A; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary., Tóth GK; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.; HUN-REN-SZTE Biomimetic Systems Research Group, Dóm tér 8, H-6720, Szeged, Hungary., Szalai TV; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; Department of Inorganic and Analytical Chemistry, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Szt. Gellért tér 4, H-1111, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Takács T; Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; Doctoral School of Biology, Institute of Biology, Eötvös Loránd University, Egyetem tér 1-3, H-1053, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., de Araujo E; Centre for Medicinal Chemistry, University of Toronto at Mississauga, Ontario, L5 L 1 C6, Mississauga, Canada., Buday L; Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Perczel A; Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, H-1117, Budapest, Hungary.; HUN-REN-ELTE Protein Modeling Research Group, Institute of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, H-1117, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary., Martinek TA; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.; HUN-REN-SZTE Biomimetic Systems Research Group, Dóm tér 8, H-6720, Szeged, Hungary., Keserű GM; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.; Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Budafoki út 8, H-1111, Budapest, Hungary.; National Drug Discovery and Development Laboratory, Magyar Tudósok Körútja 2, H-1117, Budapest, Hungary.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Sep 27, pp. e202410435. Date of Electronic Publication: 2024 Sep 27.

Enantioselective Dearomative [4+2] Cycloaddition Reaction of 1‐Naphthols with In‐Situ Generated ortho‐Quinone Methides.

Autor: Ranjan Sahoo, Sushree¹ (AUTHOR), Gupta, Khushboo¹ (AUTHOR), Singh, Vinod K.¹ (AUTHOR) vinodks@iitk.ac.in

Publikováno v: Chemistry - A European Journal. 12/11/2023, Vol. 29 Issue 69, p1-6. 6p.

Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling.

Autor: Bissegger, Lukas, Constantin, Theodora A., Keles, Erhan, Raguη, Luka, Barlow-Busch, Isobel, Orbegozo, Clara, Schaefer, Thorsten, Borlandelli, Valentina, Bohnacker, Thomas, Sriramaratnam, Rohitha, Schäfer, Alexander, Gstaiger, Matthias, Burke, John E., Borsari, Chiara, Wymann, Matthias P.

Publikováno v: Chemical Science; 12/28/2024, Vol. 15 Issue 48, p20274-20291, 18p

Characterization of the microtubule movement produced by sea urchin egg kinesin

Autor: Michael P. Sheetz, G P Vigers, Ronald D. Vale, D L Stemple, Jonathan M. Scholey, J R McIntosh, Mary E. Porter

Publikováno v: Journal of Biological Chemistry. 262:2794-2802

We have used an in vitro assay to characterize some of the motile properties of sea urchin egg kinesin. Egg kinesin is purified via 5'-adenylyl imidodiphosphate-induced binding to taxol-assembled microtubules, extraction from the microtubules in ATP,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15abb6e826e9b70bf6f6991e56005aad
https://doi.org/10.1016/s0021-9258(18)61576-5

The discovery of novel imidazo[1,2-a]pyridine derivatives as covalent anticancer agents.

Autor: Song, Qin, Zhang, Qianer, Fan, Xuejing, Kayaat, Fatmata, Lv, Ruicheng, Li, Jing, Wang, Yong

Publikováno v: Organic & Biomolecular Chemistry; 7/14/2024, Vol. 22 Issue 26, p5374-5384, 11p