Výsledky vyhledávání - "G P, Griffin"

N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes

Autor: A E, Cribb, S P, Spielberg, G P, Griffin

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 23(3)

The N4-hydroxylation of sulfamethoxazole (SMX) to its hydroxylamine (SMX-HA) metabolite is the first step in the formation of reactive metabolites responsible for mediating hypersensitivity reactions associated with this compound. In rat hepatic micr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f30899c9ace657814950ca62fee38e8
https://pubmed.ncbi.nlm.nih.gov/7628308

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Increased cosedimentation of cytosolic glutathione S-transferases with microsomal fractions prepared from frozen rat liver

Autor: A E, Cribb, G P, Griffin, S P, Spielberg, T H, Rushmore, N, Chauret, D A, Nicoll-Griffith

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 22(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23fd6ade3567b5adb9f533985ae0f27d
https://pubmed.ncbi.nlm.nih.gov/7895617

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