Zobrazeno 1 - 10
of 127
pro vyhledávání: '"G P, Biro"'
The Intravascular Persistence and Methemoglobin Formation of Hemolink™ (Hemoglobin Raffimer) in Dogs
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 31:1-17
Hemoglobin raffimer (HEMOLINK, Hemosol Inc, Mississauga, Canada) is an o-raffinose cross-linked, purified human hemoglobin-based oxygen therapeutic that is currently being evaluated in late stage clinical trials. It is composed of several molecular w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bc782db14879016a91da552b7ae19f
https://doi.org/10.1081/bio-120018000
https://doi.org/10.1081/bio-120018000
Autor:
G. P. Biro
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 28:viii-xii
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e827db561f93489553bf63499e6bfe8a
https://doi.org/10.3109/10731190009119351
https://doi.org/10.3109/10731190009119351
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 24:19-34
Anesthetized mongrel (weight range: 16-27 Kg) dogs were prepared for monitoring hemodynamics, blood flow distribution, plasma colloid osmotic pressure and renal functional parameters at various intervals. Removal of 35 ml/Kg blood resulted in marked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc18470bcb622fb77ec6265ad362d70
https://doi.org/10.3109/10731199609117428
https://doi.org/10.3109/10731199609117428
Autor:
G. P. Biro
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 22:1343-1353
Mongrel dogs were anesthetized and prepared for hemodynamic monitoring and the measurement of blood flow distribution using radionuclide-labelled microspheres (15 +/- 2 microns). Four dogs were infused with a perflubron emulsion (E) (90% w/v perflubr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1142889307374f79ca08f437b4b1fcec
https://doi.org/10.3109/10731199409138836
https://doi.org/10.3109/10731199409138836
Publikováno v:
Critical Reviews in Clinical Laboratory Sciences. 31:295-324
In this review the current status of what commonly are termed "blood substitutes" is discussed. The term blood substitute is a misnomer because the formulations under development at this time transport respiratory gases but do not perform the metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936a66a625ce13623cc5f4a0237cb922
https://doi.org/10.3109/10408369409084678
https://doi.org/10.3109/10408369409084678
Publikováno v:
Biomaterials, Artificial Cells and Immobilization Biotechnology. 20:1013-1020
Unmodified, and to a lesser extent, modified stroma-free hemoglobin preparations have been reported to exhibit coronary and renal vasoconstrictor activity in isolated perfused hearts and kidneys. The physiological significance in vivo of such ex vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bafedf1a00d5b84710121ce676e0c4b
https://doi.org/10.3109/10731199209119755
https://doi.org/10.3109/10731199209119755
Autor:
Anne-Marie Gosselin, G. P. Biro
Publikováno v:
Angiology. 41:1058-1064
The effects of low-dose (10-9 and 3x10-9 mole/kg/min) infusions of dopexamine HCl, a new synthetic catecholamine with β2-adrenergic and DA 1-dopaminergic agonostic actions, was tested in anesthetized dogs, with and without acute ligation of the left
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0c3ea1e534ad25b965ea65467b3bcf
https://doi.org/10.1177/000331979004101206
https://doi.org/10.1177/000331979004101206
Autor:
R. Stewart, M. B. Fargey, M. Bosa, J. G. Kingma, Reena Sandhu, D. Gendron, G. P. Biro, N. D. Hamelin, Y. Trudel
Publikováno v:
Artificial cells, blood substitutes, and immobilization biotechnology. 30(2)
Hemoglobin based oxygen-carrying solutions (HBOCs) as hemoglobin replacement therapeutics are being tested for clinical use. Some of these products are associated with elevations in both systemic and pulmonary vascular resistances but their effect on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad04a806131521d37f4a0f4c0b2324bb
https://pubmed.ncbi.nlm.nih.gov/11795632
https://pubmed.ncbi.nlm.nih.gov/11795632
Publikováno v:
Advances in experimental medicine and biology. 388
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bd895270dc62d95c1e873be42e46b6d
https://pubmed.ncbi.nlm.nih.gov/8798866
https://pubmed.ncbi.nlm.nih.gov/8798866
Publikováno v:
Artificial cells, blood substitutes, and immobilization biotechnology. 23(6)
Hypovolemic states are characterized by inadequate tissue perfusion; when this state is reversed, the reintroduction of oxygen is accompanied by the excess generation of oxyradicals and these, in turn, may cause "reperfusion injury" in susceptible ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd153b05b6aceca5302dbfc6b34a982
https://pubmed.ncbi.nlm.nih.gov/8556138
https://pubmed.ncbi.nlm.nih.gov/8556138