Výsledky vyhledávání - "G O Young-Cooper"

VH gene expression and regulation in the mutant Alicia rabbit. Rescue of VHa2 allotype expression

Autor: H T Chen, C B Alexander, G O Young-Cooper, R G Mage

Publikováno v: The Journal of Immunology. 150:2783-2793

Rabbits of the Alicia strain, derived from rabbits expressing the VHa2 allotype, have a mutation in the H chain locus that has a cis effect upon the expression of VHa2 and VHa- genes. A small deletion at the most J-proximal (3') end of the VH locus l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37b9ba4c147e1a2d41c2db738e72bc65
https://doi.org/10.4049/jimmunol.150.7.2783

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Identification of enhancer sequences 3' of the rabbit Ig kappa L chain loci

Autor: N J Hole, N Harindranath, G O Young-Cooper, R Garcia, R G Mage

Publikováno v: The Journal of Immunology. 146:4377-4384

The rabbit is useful for studies of Ig L chain gene expression because of a great disparity in expression of two isotypic forms of the kappa L chain. Normally, K1 is expressed at high levels and K2 is almost silent; expression of K2 increases in muta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f8d4c93c71963e9aa4bbe51a333cc1f
https://doi.org/10.4049/jimmunol.146.12.4377

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Anti-hapten IgG antibodies bound to cell surface hapten: anti-IgG antibody prevents dissociation as measured with fluid phase hapten

Autor: T Borsos, A Circolo, G O Young-Cooper, R Mage

Publikováno v: The Journal of Immunology. 136:224-229

We investigated the dissociation by fluid phase hapten of IgG antibodies bound to cell surface hapten in the presence and absence of anti-IgG antibodies. Dissociation was quantitated with fluid phase hapten, preventing reassociation of the anti-hapte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a137cf202d624d2833fdf84f25d39ff
https://doi.org/10.4049/jimmunol.136.1.224

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Rabbit immunoglobulin allotypes: complexities of their genetics, expression, structural basis, and evolution

Autor: G. O. Young-Cooper, J. Rejnek, Ettore Appella, R. G. Mage, Cornelius B. Alexander, S. Landucci-Tosi, Aftab A. Ansari, M. Carta-Sorcini, R. M. Tosi

Publikováno v: Cold Spring Harbor symposia on quantitative biology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7cfb17ce208f6146c22774b4999040
https://pubmed.ncbi.nlm.nih.gov/268252

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Rabbit allotypes--tools for the examination of gene expression in lymphoid differentiation

Autor: R G, Mage, G O, Young-Cooper, M R, Harrison

Publikováno v: Society of General Physiologists series. 29

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9b6732426cb282eb5d524d340b248df
https://pubmed.ncbi.nlm.nih.gov/4139763

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Linked genetic markers of the rabbit kappa light chain are not linked to the Tcr beta chain genes

Autor: N J, Hole, E, Lamoyi, M, Komatsu, N, Harindranath, G O, Young-Cooper, R G, Mage

Publikováno v: Immunogenetics. 28(2)

In order to investigate linkage, we used serum allotypes of the two rabbit C kappa isotypes and restriction fragment length polymorphisms (RFLPs) of the genes for V kappa, C kappa, and T-cell receptor C beta. The inheritance of these genetic markers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a8a005e19fe5d21ee28ae3f32425f58
https://pubmed.ncbi.nlm.nih.gov/2899549

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