Zobrazeno 1 - 10
of 19
pro vyhledávání: '"G O Emerole"'
Publikováno v:
European Journal of Cancer Prevention. 14:207-214
The chemopreventive effects of kolaviron, a natural antioxidant bioflavonoid from the seeds of Garcinia kola, on aflatoxin B1 (AFB1)-induced genotoxicity and hepatic oxidative damage was investigated in rats. Kolaviron administered orally at a dose o
Autor:
O. Adesanoye, G. O. Emerole, O. O. Obodozie, A. O. Olusola, L. E. Odama, A. Adaramoye, M. Nssien
Publikováno v:
Biological Trace Element Research. 98:265-274
The concentrations of copper, iron, and zinc in the major organs of Wistar albino (Rattus norvegicus) and wild black rats (Rattus rattus) were measured by means of atomic absorption spectroscopy. The copper levels in the kidneys and liver of the Wist
Publikováno v:
African journal of medicine and medical sciences. 34(1)
The modulatory effect of glutathione levels on markers for aflatoxin B1 (AFB1)-induced cell damage has been investigated in the rat (susceptible specie) and the (mouse resistant specie). The concentration of GSH was depleted and increased by administ
Publikováno v:
African journal of medicine and medical sciences. 29(2)
The modulatory effect of browned yam flour diet, a dietary, staple in south-western Nigeria, on carbon tetrachloride (CCl4)-mediated lipid peroxidation and on the activities of liver microsomal and cytosolic enzymes was studied in male rats. Browned
Publikováno v:
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 9(5)
Kolaviron biflavonoids have demonstrated antihepatotoxic activity in animal studies. The present study investigated the possible chemopreventive potential of kolaviron in inhibiting aflatoxin B1 (AFB1) genotoxicity in HepG2 cells. Kolaviron inhibitio
Publikováno v:
European Journal of Cancer Prevention; Jun2005, Vol. 14 Issue 3, p207-214, 8p
Autor:
A. O. Olusola, O. O. Obodozie, M. Nssien, A. Adaramoye, O. Adesanoye, L. E. Odama, G. O. Emerole
Publikováno v:
Biological Trace Element Research; 6/1/2004, Vol. 98 Issue 3, p265-274, 10p
Publikováno v:
Xenobiotica. 9:737-743
1. The deactivation of aflatoxin B1 by glutathione (GSH) has been investigated in rat. Binding of metabolites of aflatoxin B1 to [3H]glutathione in vitro with rat liver microsomes is insignificant. Incubation with rat liver 10 000 g supernatant resul
Autor:
M I, Thabrew, G O, Emerole
Publikováno v:
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. 74(2)
1. The effects of the herbicide 1.1.1. trifluoro-N-(2-methyl-4-phenyl sulfonyl phenyl) methane sulfonamide on the drug metabolising enzyme activities in livers of rat, mouse and guinea pig have been compared. 2. In all three animal models, the herbic
Autor:
G O, Emerole, M I, Thabrew
Publikováno v:
Research communications in chemical pathology and pharmacology. 31(3)
Homogenates and 10,000 g fractions obtained from lungs of rats (wister strain) and albino mice produced a fluorescent metabolite of aflatoxin B1, with similar Rf value and ultraviolet characteristics as aflatoxicol obtained from the liver of duck. Th