Zobrazeno 1 - 10
of 18
pro vyhledávání: '"G O, POTTS"'
Publikováno v:
Agents and Actions. 25:164-170
The purpose of the study was to determine if danazol was efficacious in the treatment of lupus MRL/MpJ (lpr) mice, as measured by longevity, proteinuria and serum amyloid protein (SAP) levels. Danazol, administered at an oral dose of 100 mg/kg, signi
Autor:
G. O. Potts, H.P. Schane
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 47:691-694
Spironolactone has progestational activity in the rabbit and rhesus monkey. It produced glandular development in the endometrium of the estrogen-primed immature female rabbit over the dosage range of 50 to 200 mg/kg and, at 400 mg/monkey, it delayed
Autor:
G O, Potts
Publikováno v:
The Journal of international medical research. 5
We have established that danazol is an orally active pituitary gonadotrophin inhibitory agent devoid of oestrogenic and progestational activity. This steroid has weak, impeded androgenic activity. Danazol is unique in possessing such a profound separ
Publikováno v:
Drugs. 19(5)
Publikováno v:
Fertility and sterility. 30(1)
Azastene (4,4,17alpha-trimethylandrost-5-eno[2,3-d]isoxazol-17-ol), when given orally to rats at a dose of 12 mg/kg once on day 10 of pregnancy, induced resorption of all fetuses and a precipitous decline of circulating progesterone levels in all tes
Publikováno v:
Biology of reproduction. 40(3)
The objective of these studies was to determine whether treatment of 10-day pregnant rats with a combination of epostane (a progesterone biosynthesis inhibitor) and either ZK 98299 or ZK 98734 (progesterone receptor antagonists) would result in addit
Publikováno v:
Fertility and sterility. 30(3)
Azastene is an orally effective "luteolytic" agent in rhesus monkeys. In nonpregnant monkeys it reverses the human chorionic gonadotropin-stimulated increase in progesterone production and delay in the onset of menstruation, and, in inseminated monke
Publikováno v:
Medical times. 91
Publikováno v:
Endocrinology. 67
Publikováno v:
Journal of medicinal chemistry. 7