Zobrazeno 1 - 10
of 45
pro vyhledávání: '"G Nicholas Europe-Finner"'
Autor:
Jonathan Baker, Adrian M D Falconer, David J Wilkinson, G Nicholas Europe-Finner, Gary J Litherland, Andrew D Rowan
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195864 (2018)
Many catabolic stimuli, including interleukin-1 (IL-1) in combination with oncostatin M (OSM), promote cartilage breakdown via the induction of collagen-degrading collagenases such as matrix metalloproteinase 1 (MMP1) and MMP13 in human articular cho
Externí odkaz:
https://doaj.org/article/dd7b44edb653406f81df8918086f1e74
Autor:
Christopher D Macdonald, Adrian M D Falconer, Chun Ming Chan, David J Wilkinson, Andrew Skelton, Louise Reynard, Gary J Litherland, G Nicholas Europe-Finner, Andrew D Rowan
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207240 (2018)
Irreversible cartilage collagen breakdown by the collagenolytic matrix metalloproteinases (MMPs)-1 and MMP-13 represents a key event in pathologies associated with tissue destruction such as arthritis. Inflammation is closely associated with such pat
Externí odkaz:
https://doaj.org/article/6794cdb9cbfc432f992af1601bd2260d
Autor:
David J. Wilkinson, Andrew D. Rowan, G. Nicholas Europe-Finner, Jonathan R. Baker, Gary J. Litherland, Adrian M. D. Falconer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0195864 (2018)
PLoS ONE, Vol 13, Iss 4, p e0195864 (2018)
Many catabolic stimuli, including interleukin-1 (IL-1) in combination with oncostatin M (OSM), promote cartilage breakdown via the induction of collagen-degrading collagenases such as matrix metalloproteinase 1 (MMP1) and MMP13 in human articular cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cae732f3a558b3a0b6b30840aefa4d4
http://hdl.handle.net/10044/1/60674
http://hdl.handle.net/10044/1/60674
Autor:
Achim, Treumann, Pawel, Palmowski, Wing Chiu, Tong, Julie, Taggart, Nick, Morrice, G, Nicholas Europe-Finner, Michael J, Taggart
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1788
Muscle tissue poses a particular challenge to proteomic analysis due to a very wide range of protein abundances arising from the dominant expression of myofilament-related proteins. We address this issue by describing proteomic analysis with liquid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cf09f7f42c800169f3614bc7df89e2d
https://pubmed.ncbi.nlm.nih.gov/28975594
https://pubmed.ncbi.nlm.nih.gov/28975594
Autor:
Michael J. Taggart, G. Nicholas Europe-Finner, Pawel Palmowski, Julie Taggart, Achim Treumann, Nick Morrice, Wing Chiu Tong
Publikováno v:
Methods in Molecular Biology ISBN: 9781493978526
Muscle tissue poses a particular challenge to proteomic analysis due to a very wide range of protein abundances arising from the dominant expression of myofilament-related proteins. We address this issue by describing proteomic analysis with liquid c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466a95dfec19a2f1462aa7d7ae506e4d
https://doi.org/10.1007/7651_2017_73
https://doi.org/10.1007/7651_2017_73
Autor:
Magdalena Karolczak-Bayatti, Andrew Porter, Rachael Watson, Pawel Palmowski, G. Nicholas Europe-Finner, Achim Treumann, Michael J. Taggart
Publikováno v:
Proteomics
Advances in liquid chromatography‐mass spectrometry have facilitated the incorporation of proteomic studies to many biology experimental workflows. Data‐independent acquisition platforms, such as sequential window acquisition of all theoretical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e547d69c981697712388fe15405791f2
https://doi.org/10.1002/pmic.201900156
https://doi.org/10.1002/pmic.201900156
Autor:
Steve J. Webster, Averil Y. Warren, Raheela N. Khan, Neil Chapman, Saurabh V. Gandhi, Sarah L. Waite, G. Nicholas Europe-Finner, Victoria J. Cookson
Publikováno v:
Journal of Biological Chemistry. 288:6704-6716
The onset of parturition is associated with a number of proinflammatory mediators that are themselves regulated by the nuclear factor κB (NF-κB) family of transcription factors. In this context, we previously reported that the RelA NF-κB subunit r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd0fa1f8d75f961657e5da353be82cd7
https://doi.org/10.1074/jbc.m112.440602
https://doi.org/10.1074/jbc.m112.440602
Publikováno v:
Reproductive Sciences. 20:175-181
Posttranslational modifications (PTMs) of proteins by phosphorylation are a well-established mechanism by which their activities can be regulated to affect cellular physiology. However, it is becoming increasingly evident that PTMs of proteins by ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f565d73aba50dbec9fb05b7ff415687
https://doi.org/10.1177/1933719111432876
https://doi.org/10.1177/1933719111432876
Autor:
Andrew D. Rowan, Gary J. Litherland, Andrew J. Skelton, Chun Ming Chan, David J. Wilkinson, Christopher D. Macdonald, G. Nicholas Europe-Finner
Publikováno v:
The Journal of biological chemistry. 292(5)
Irreversible breakdown of cartilage extracellular matrix (ECM) by the collagenase matrix metalloproteinase 13 (MMP13) represents a key event in osteoarthritis (OA) progression. Although inflammation is most commonly associated with inflammatory joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c846250dfe4923f1ceeac663dbd5e6e
https://pubmed.ncbi.nlm.nih.gov/27956552
https://pubmed.ncbi.nlm.nih.gov/27956552
Autor:
Joanna Cheng, Achim Treumann, M Sweeney, Lydia Edey, Magadalena Karolczak-Bayatti, Scott M. Ulrich, Michael J. Taggart, Stephen C. Robson, G. Nicholas Europe-Finner
Publikováno v:
Journal of Biological Chemistry. 286:34346-34355
Phosphorylation of heat shock protein 20 (Hsp20) by protein kinase A (PKA) is now recognized as an important regulatory mechanism modulating contractile activity in the human myometrium. Thus agonists that stimulate cyclic AMP production may cause re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8c3d0bcca3d9fc2262b477b58b091a
https://doi.org/10.1074/jbc.m111.278549
https://doi.org/10.1074/jbc.m111.278549