Zobrazeno 1 - 10
of 72
pro vyhledávání: '"G Nguyen-Ba"'
Publikováno v:
Environmental Toxicology and Pharmacology. 11:191-196
In order to understand the c- myc implication in the apoptotic process better, we investigated the influence of ZnCl 2 on its expression in normal and transformed Syrian hamster embryo (SHE) cells in relation to apoptosis induced by serum withdrawal.
Publikováno v:
Biomedicine & Pharmacotherapy. 56:200-207
Polyphenols are the most abundant antioxidants in our diets. The main classes of polyphenols are phenolic acids (mainly caffeic acid) and flavonoids (the most abundant in the diet are flavanols (catechins plus proanthocyanidins), anthocyanins and the
Publikováno v:
Toxicological & Environmental Chemistry. 81:153-160
Cadmium and chlordane are compounds chosen for a preliminary study on the impact of environmental contaminants on apoptosis in different representative species. These two potentially toxic substances decrease in vitro apoptosis of Daphnia magna cells
Publikováno v:
Experimental Cell Research. 255:30-39
The sensitivity of normal diploid Syrian hamster embryo (SHE) cells to apoptosis was tested after treatment with the topoisomerase inhibitors camptothecin and etoposide and after serum withdrawal. Programmed cell death (PCD) was identified through mo
Autor:
Nicole Pages, Laurent Gate, Véronique Cruciani, Haim Tapiero, Zoé Elias, Halima Bessi, G Nguyen-Ba, O. Poirot, C. Rast, Paule Vasseur, S. Dhalluin
Publikováno v:
International Journal of Cancer. 75:744-749
As part of environmental toxicology, it is important to assess both the carcinogenic potential of xenobiotics and their mode of action on target cells. Since dysregulation of ornithine decarboxylase (ODC), a rate-limiting enzyme of polyamine biosynth
Autor:
Halima Bessi, G Nguyen-Ba, C. Rast, Paule Vasseur, Stéphanie Alexandre, Marie-José Durand, Véronique Cruciani
Publikováno v:
Polycyclic Aromatic Compounds. 10:307-314
The Syrian hamster embryo (SHE) cell transformation assay is an in vitro method for the detection of genotoxic and non-genotoxic carcinogens. Its reliability as a multistage carcinogen screening method was demonstrated by several authors who showed t
Autor:
W Jongen, Kaija Linnainmaa, S Parodi, J.W.I.M. Simons, John Ashby, G Nguyen-Ba, Edgar Rivedal, Hiroshi Yamasaki, Paule Vasseur, Margherita Bignami, R.F Newbold, Dietmar Schiffmann
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 353:47-63
While the accumulation of genetic changes in a somatic cell is considered essential for the genesis of a cancer, it has become clear that not all carcinogens are genotoxic, suggesting that some carcinogens indirectly participate in the generation of
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 57(7)
Anthracyclines are the most commonly used classes of anticancer agents in chemotherapy. Development of resistance to these molecules is one of the major reasons for treatment failure. The overexpression of the membrane transporter P-glycoprotein (P-g
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 56(5)
Linoleic and alpha-linolenic acids, obtained from plant material in the diet are the precursors in tissues of two families with opposing effects which are referred to as “essential fatty acids” (EFA): arachidonic acid (AA) and pentaene (eicosapen
Publikováno v:
Biochimie. 82(12)
In this study, we attempted to identify apoptotic Syrian hamster embryo (SHE) cells by detecting the specific cleavage of poly(ADP-ribose)polymerase (PARP). Apoptosis was unequivocally identified in serum-deprived SHE cells. After protein electrophor