Zobrazeno 1 - 10
of 325
pro vyhledávání: '"G N Pavlakis"'
Autor:
Jenifer Bear, Oleg Chertov, J. Lifson, Morten Thaysen-Andersen, Edward S. X. Moh, R. Sowder, J. Roser, Nicolle H. Packer, Cristina Bergamaschi, G. N. Pavlakis, B. K. Felber, Elena Chertova
Publikováno v:
Glycoconj J
Europe PubMed Central
Europe PubMed Central
Human interleukin 15 (IL-15) circulates in blood as a stable molecular complex with the soluble IL-15 receptor alpha (sIL-15Rα). This heterodimeric IL-15:sIL-15Rα complex (hetIL-15) shows therapeutic potential by promoting the growth, mobilization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da889fbcfecefee0bddc1d996ae0f8f
https://pubmed.ncbi.nlm.nih.gov/26563299
https://pubmed.ncbi.nlm.nih.gov/26563299
Autor:
Luigi Chieco-Bianchi, Jeanette Harrison, Antonio Rosato, G. N. Pavlakis, Daniela Saggioro, Gianni Esposito, Barbara K. Felber, Michael P. Rosenberg
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 14:272-280
Transgenic mice carrying the tax gene of human T-cell lymphotropic virus type I displayed a high prevalence of arthropathy. The percentage of affected animals increased with age, reaching a peak of 43% at 20 months. Southern analysis of deoxyribonucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77e460c69cf3f1f89aaff24a0d8e038
https://doi.org/10.1097/00042560-199703010-00012
https://doi.org/10.1097/00042560-199703010-00012
Autor:
C M Drysdale, G N Pavlakis
Publikováno v:
Journal of Virology. 65:3044-3051
The mechanism of induction of gene expression of the human immunodeficiency virus type 1 long terminal repeat (LTR) by the Tat transactivator protein was studied in a cell fusion assay. Tat causes a rapid activation of both transcription from the LTR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d140239f652743a0aaa1413739dea3
https://doi.org/10.1128/jvi.65.6.3044-3051.1991
https://doi.org/10.1128/jvi.65.6.3044-3051.1991
Publikováno v:
Journal of Virology. 64:3734-3741
Rev is an essential regulatory protein of the human immunodeficiency virus type 1 (HIV-1) that affects the transport and half-life of certain viral mRNAs. Rev exerts its function via a unique element, the Rev-responsive element (RRE), located within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56248f0217089449cf9288dac4f97dd4
https://doi.org/10.1128/jvi.64.8.3734-3741.1990
https://doi.org/10.1128/jvi.64.8.3734-3741.1990
Autor:
M.J. Saltarelli, T.J. Spira, Barbara K. Felber, C.E. Hart, Jeanette Harrison, Emilia Hadziyannis, G. N. Pavlakis
Publikováno v:
AIDS research and human retroviruses. 12(15)
HIV-1 produces more than 20 mRNAs encoding the viral proteins. We have used a sensitive reverse transcriptase-polymerase chain reaction (RT-PCR) approach to determine HIV-1 transcriptional patterns during the course of viral infection in unstimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e917634810576281e53d3b0795144a
https://pubmed.ncbi.nlm.nih.gov/8893052
https://pubmed.ncbi.nlm.nih.gov/8893052
Publikováno v:
Virology. 213(2)
Expression of gag/pol and env genes of human immunodeficiency virus requires the viral Rev protein. Mutant Rev proteins, displaying a transdominant phenotype (TDRev), were shown to inhibit Rev function. To investigate the underlying mechanism of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cf397253cd2da98ba7de9e5a9cb851a
https://pubmed.ncbi.nlm.nih.gov/7491768
https://pubmed.ncbi.nlm.nih.gov/7491768
Publikováno v:
AIDS research and human retroviruses. 11(9)
We have explored the mechanism directing the intracellular trafficking and nucleolar accumulation of the human immunodeficiency virus type 1 (HIV-1) Rev protein. Treatment of Rev-expressing cells with mycophenolic acid, an inhibitor of inosine monoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db796f07e147e3e0d1e444184dc9b3dd
https://pubmed.ncbi.nlm.nih.gov/8554903
https://pubmed.ncbi.nlm.nih.gov/8554903
Publikováno v:
The Journal of biological chemistry. 269(3)
The translocation (6;9) in acute nonlymphocytic leukemia results in the formation of a dek-can fusion gene. In a case of acute undifferentiated leukemia, the oncogene can is fused to a different gene, named set, instead of dek and is assumed to be ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a44703a6c3dcabd572b2402c1102a7c1
https://pubmed.ncbi.nlm.nih.gov/8294483
https://pubmed.ncbi.nlm.nih.gov/8294483
Molecular biology of HIV-1: positive and negative regulatory elements important for virus expression
Autor:
B K, Felber, G N, Pavlakis
Publikováno v:
AIDS (London, England). 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02c5ec959f446a05f91d8ea5a017450a
https://pubmed.ncbi.nlm.nih.gov/8363803
https://pubmed.ncbi.nlm.nih.gov/8363803
Autor:
D J, Clanton, R A, Moran, J B, McMahon, O S, Weislow, R W, Buckheit, M G, Hollingshead, V, Ciminale, B K, Felber, G N, Pavlakis, J P, Bader
Publikováno v:
Journal of acquired immune deficiency syndromes. 5(8)
Over 50 different commercially available sulfonic acid-containing dyes were analyzed for their ability to prevent HIV-1-induced cell killing and in inhibiting HIV-1 replication. Compounds of remarkably similar structure, but with differing patterns o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0f2e1518afbfb3f958e9c24a1506b3d
https://pubmed.ncbi.nlm.nih.gov/1517963
https://pubmed.ncbi.nlm.nih.gov/1517963