Zobrazeno 1 - 10
of 20
pro vyhledávání: '"G N Mir"'
Autor:
E Z, Dajani, K R, Larsen, J, Taylor, N E, Dajani, T G, Shahwan, S D, Neeleman, M S, Taylor, M T, Dayton, G N, Mir
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(1)
1',1'-Dimethylheptyl-Delta-8-tetrahydrocannabinol-11-oic acid (CT-3) is a novel cannabinoid that is under development by Atlantic Pharmaceuticals as an anti-inflammatory and analgesic drug. The objective of the study was to investigate the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ecd9194da7a5a2078c0d8ee89946b8e
https://pubmed.ncbi.nlm.nih.gov/10490883
https://pubmed.ncbi.nlm.nih.gov/10490883
Publikováno v:
Agents and Actions. 6:735-747
Fenclorac (a,m-dichloro-p-cyclohexlphenylacetic acid, diethylammonium salt) is a potent nonsteroidal anti-inflammatory agent with significant analgesic and antipyretic activity. Fenclorac had an ED50 of 7.9 mg/kg in the carrageenan paw edema assay an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c498e4cd28b64b44e0fb52f5ef134c06
https://doi.org/10.1007/bf02026097
https://doi.org/10.1007/bf02026097
Publikováno v:
Arzneimittel-Forschung. 38(3)
The antisecretory activities of 4-(dimethylamino)- N-[2-[3-[3-(1-piperidinyl)methyl]phenoxy]propyl]amino]- 1,2,5-thiadiazol-4-yl]amino]ethyl]-butanamide, S-oxide (AY-29,315) and ranitidine were determined in the rat, dog and monkey. In conscious, chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddb989608ba384e44239012469584c9f
https://pubmed.ncbi.nlm.nih.gov/2898247
https://pubmed.ncbi.nlm.nih.gov/2898247
Publikováno v:
Arzneimittel-Forschung. 28(8a)
1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) has been reported to be a potent antidiarrheal agent in laboratory animals. This study defines its effects on the cardiovascular and central nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6cd1ff67860458027833331d19b330f
https://pubmed.ncbi.nlm.nih.gov/582537
https://pubmed.ncbi.nlm.nih.gov/582537
Publikováno v:
Arzneimittel-Forschung. 28(8a)
The acute oral LD50 of 1-(2,6-dimethylphenyl)-3-amidinourea hydrochloride (WHR-1142A, lidamidine hyrochloride) was 260 (208, 328) mg/kg in male mice, 267 (212, 336) mg/kg in male rats and 160 (130, 197) mg/kg in female rats. A daily oral dose of 10 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4a67097e8a310ada51b2017a9ceeb6e
https://pubmed.ncbi.nlm.nih.gov/113015
https://pubmed.ncbi.nlm.nih.gov/113015
Publikováno v:
Arzneimittel-Forschung. 39(7)
The cytoprotective and antiulcer activities of the antacid magaldrate (ES Riopan) as well as its effects on gastric mucosal blood flow and mucus secretions, were determined in the rat. Magaldrate afforded protection against gastric necrotic lesions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::789a773df9d72aec5517333b9ca5a5b7
https://pubmed.ncbi.nlm.nih.gov/2783181
https://pubmed.ncbi.nlm.nih.gov/2783181
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 241(1)
The gastric antisecretory and antiulcer effects of a novel compound, [1-(2,-dimethylphenyl)-3-isobutoxyamidinourea]hydrochloride (WHR1582A), are described. WHR1582A was active in preclinical ulcer models induced by 18-hr pylorus ligation, aspirin, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f208547b45b2da9d4a90c4dc121d2b40
https://pubmed.ncbi.nlm.nih.gov/2883297
https://pubmed.ncbi.nlm.nih.gov/2883297
Publikováno v:
Agents and actions. 6(6)
Fenclorac (a,m-dichloro-p-cyclohexlphenylacetic acid, diethylammonium salt) is a potent nonsteroidal anti-inflammatory agent with significant analgesic and antipyretic activity. Fenclorac had an ED50 of 7.9 mg/kg in the carrageenan paw edema assay an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff057eb4878abcb998cfffd63e765fd8
https://pubmed.ncbi.nlm.nih.gov/1008019
https://pubmed.ncbi.nlm.nih.gov/1008019
Publikováno v:
Arzneimittel-Forschung. 28(8a)
1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A), lidamidine hydrochloride), a novel antidiarrheal agent, inhibited contractile activity in isolated guinea pig ileum stimulated by acetylcholine, histamine, serotonin, dimethylpheny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc3057816d58116a2a3d584741eb463e
https://pubmed.ncbi.nlm.nih.gov/89850
https://pubmed.ncbi.nlm.nih.gov/89850
Publikováno v:
Life sciences. 35(10)
Alpha-2 receptor activation mediates the inhibition of a number of gastrointestinal functions including gastric and intestinal secretions. Alpha-2 receptors are located in the brain and presynaptically on cholinergic nerve terminals; activation of ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03be9f86756e63b0b51990c0560612c5
https://pubmed.ncbi.nlm.nih.gov/6148675
https://pubmed.ncbi.nlm.nih.gov/6148675