Zobrazeno 1 - 10 of 30 pro vyhledávání: '"G N Gaulton"'
2
New T-lymphocytic cell lines for studying cell infectability by human immunodeficiency virus
Autor: T, Rozmyslowicz, J, Kijowski, D O, Conover, M, Majka, M, Baj-Krzyworzeka, R, Reca, J J, Libura, G N, Gaulton, M Z, Ratajczak
Publikováno v: European journal of haematology. 67(3)
We identified five human T-lymphoid cell lines (PB-1, Sez-4, C19PL, HUT 102B and ATL-2) which highly express CD4 in addition to CXCR4 and CCR5. In order to evaluate if these cells are infectabile by human immunodeficiency virus (HIV) and could be emp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75c88d9a9e732b0cc1a33cb28aeabf4f
https://pubmed.ncbi.nlm.nih.gov/11737246
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4
The role of the immune response in MULV-induced lymphomagenesis
Autor: D J, Marshall, G N, Gaulton
Publikováno v: Leukemia. 10(12)
Although the exact mechanisms of murine leukemia virus (MuLV)-induced lymphomagenesis have yet to be elucidated, it is clear that the immune reponse to viral proteins plays a critical role in this disease process. The parameters for lymphomagenesis a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ebff40fe183a7a059541cd344c76eeb
https://pubmed.ncbi.nlm.nih.gov/8946922
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5
Manipulation of the immune response by foreign gene expression in the thymus
Autor: D J, Marshall, B H, Park, J M, Korostoff, G N, Gaulton
Publikováno v: Leukemia. 9
Retroviral gene transfer vectors have been developed for optimal in vivo gene therapy. Ideally, these vectors should target gene expression specifically to selected tissues or organs. Our studies focus on the development of retroviral vectors for gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::07dcd84e55c124686a165caffde339be
https://pubmed.ncbi.nlm.nih.gov/7475305
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6
Neonatal HIV-1 thymic infection
Autor: M, Rosenzweig, E M, Bunting, G N, Gaulton
Publikováno v: Leukemia. 8
The thymus is the primary site of T cell ontogeny and selection during fetal and neonatal development. Previous studies have established that the thymus is also a site of HIV-1 infection, as early as the first trimester of pregnancy. Alteration of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ece5f15203c7b0a3fce4c0f8b1a260a9
https://pubmed.ncbi.nlm.nih.gov/8152285
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8
Pathogenesis of cerebral infarction and hemorrhage induced by a murine leukemia virus
Autor: B H, Park, E, Lavi, A, Stieber, G N, Gaulton
Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 70(1)
Inoculation of neonatal BALB/c mice with the Friend murine leukemia virus TR1.3 uniformly induces cerebral infarctions and hemorrhages within 18 days. The primary target of TR1.3 infection are endothelial cells of capillaries and small vessels. Preli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d377cd4bc0814aa714ee41a4a0acf11d
https://pubmed.ncbi.nlm.nih.gov/8302022
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9
Inhibition of T cell antigen receptor-dependent phosphorylation of CD4 in human immunodeficiency virus type 1 infected cells
Autor: G N, Gaulton, L F, Brass, D, Kozbor, C H, Pletcher, J A, Hoxie
Publikováno v: The Journal of biological chemistry. 267(6)
Inhibitory effects of human immunodeficiency virus (HIV) on T lymphocyte function have been linked to perturbation of signaling through the T cell antigen receptor-CD3 complex. Comparative biochemical analyses of signaling responses were performed in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::deb5173273231add28344dc5231a4476
https://pubmed.ncbi.nlm.nih.gov/1310988
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10
T4 endocytosis and phosphorylation induced by phorbol esters but not by mitogen or HIV infection
Autor: J A Hoxie, J L Rackowski, B S Haggarty, G N Gaulton
Publikováno v: The Journal of Immunology. 140:786-795
The T4 (CD4) molecule has been shown to facilitate the interactions of T cells with HLA class II determinants, to function as a signal transducing molecule, and to serve as a receptor for HIV. Recent studies demonstrated that both phorbol esters and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bd769a741343b37b02d82e5e4c750fd
https://doi.org/10.4049/jimmunol.140.3.786
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