Zobrazeno 1 - 10
of 293
pro vyhledávání: '"G N, Hendy"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 80:60-64
The amino-terminal fragments of human PTH [hPTH-(1-34)] and PTH-related peptide [PTHrP-(1-34)] appear to be equipotent in several rodent models. However, continuous i.v. infusions of these peptides to young human volunteers suggested that a 10-fold h
Autor:
Xu, Junfeng1,2,3,4,5 (AUTHOR), Lou, Xin1,2,3,4,5 (AUTHOR), Wang, Fei1,2,3,4,5 (AUTHOR), Zhang, Wuhu1,2,3,4,5 (AUTHOR), Xu, Xiaowu1,2,3,4,5 (AUTHOR), Ye, Zeng1,2,3,4,5 (AUTHOR), Zhuo, Qifeng1,2,3,4,5 (AUTHOR), Wang, Yan1,2,3,4,5 (AUTHOR), Jing, Desheng1,2,3,4,5 (AUTHOR), Fan, Guixiong1,2,3,4,5 (AUTHOR), Chen, Xuemin6 (AUTHOR), Zhang, Yue6 (AUTHOR), Zhou, Chenjie1,2,3,4,5 (AUTHOR), Chen, Jie1,2,3,4,5 (AUTHOR) chenjie@fudanpci.org, Qin, Yi1,2,3,4,5 (AUTHOR) qinyi@fudanpci.org, Yu, Xianjun1,2,3,4,5 (AUTHOR) yuxianjun@fudanpci.org, Ji, Shunrong1,2,3,4,5 (AUTHOR) jishunrong@fudanpci.org
Publikováno v:
Advanced Science. 9/18/2024, Vol. 11 Issue 35, p1-21. 21p.
Autor:
N. G. Seidah, Claude Lazure, François Jean, Michel Chrétien, Normand Rondeau, Ajoy Basak, Suzanne Benjannet, G. N. Hendy
Publikováno v:
Biochemical Journal. 292:891-900
Prohormone convertase-1 (PC1), an endopeptidase that is structurally related to the yeast subtilisin-like Kex2 gene product, has been proposed to be involved in mammalian tissue-specific prohormone processing at pairs of basic residues. To better stu
Autor:
K Jonas, Anthony B. Hodsman, J E Henderson, C I Rose, L J Fraher, D Goltzman, G N Hendy, D Saunders
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 75:417-423
PTH-related peptide (PTHrP) is one of the etiological factors associated with hypercalcemia of malignancy in humans and rodents. In both in vivo and in vitro animal systems its actions mimic those of PTH; however, its bioactivity in humans has not pr
Autor:
G N, Hendy
Publikováno v:
Reviews in endocrinemetabolic disorders. 1(4)
Several advances have been achieved toward the goal of understanding the molecular basis of parathyroid tumorigenesis. The cyclin D1/PRAD1 oncogene has been identified, and is involved in the development of several different tumor types besides those
Publikováno v:
Cytogenetics and cell genetics. 94(1-2)
Autor:
M, Minagawa, T, Watanabe, Y, Kohno, H, Mochizuki, G N, Hendy, D, Goltzman, J H, White, T, Yasuda
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(3)
Hypocalcemia and hyperphosphatemia caused by PTH resistance are the only discernible abnormalities in pseudohypoparathyroidism type 1b (PHP-1b). Because of the selective resistance toward PTH, inactivating mutations in its receptor, the PTH/PTH-relat
Publikováno v:
The Journal of biological chemistry. 276(6)
Liver cells respond to changes in Ca(2+)(o). The hepatic functions affected include bile secretion, metabolic activity, liver regeneration, and the response to xenobiotics. In the present study, we demonstrate the presence, in the liver, of the extra
Publikováno v:
Human mutation. 16(4)
The calcium-sensing receptor (CASR) is a plasma membrane G protein coupled receptor that is expressed in the parathyroid hormone (PTH) producing chief cells of the parathyroid gland and the cells lining the kidney tubule. By virtue of its ability to
Publikováno v:
Cytogenetics and cell genetics. 86(3-4)
Diverse cellular functions are regulated by the calcium-sensing receptor, encoded by the CASR gene, which plays an important role in calcium homeostasis. Here we provide the sequence for exon VII of the rabbit CASR gene and show that it is 91% identi