Zobrazeno 1 - 9
of 9
pro vyhledávání: '"G N, Bijur"'
Autor:
Richard S. Jope, G N Bijur
Publikováno v:
Molecular psychiatry. 7
Glycogen synthase kinase-3beta (GSK3beta) is a central figure in many intracellular signaling systems and is directly regulated by lithium. Substantial evidence now indicates that an important property of the mood stabilizer, lithium, is to influence
Publikováno v:
Journal of neuroscience research. 61(5)
The effects of an oxidative insult on cell survival and tau metabolism were investigated in human neuroblastoma SH-SY5Y cells. In this treatment paradigm cells were exposed to the membrane permeant oxidant tert-butylhydroperoxide (tBHP) for 40 min, r
Publikováno v:
The Journal of biological chemistry. 275(11)
The potential role of glycogen synthase kinase-3beta in modulating apoptosis was examined in human SH-SY5Y neuroblastoma cells. Staurosporine treatment caused time- and concentration-dependent increases in the activities of caspase-3 and caspase-9 bu
Publikováno v:
Environmental and molecular mutagenesis. 33(2)
Reactive oxygen species induce cellular damage and have been implicated as mediators for cellular signaling pathways. However, a linkage between the cellular redox status and cell cycle progression has not been demonstrated. We previously demonstrate
Publikováno v:
Environmental and molecular mutagenesis. 31(4)
It has been suggested that reactive oxygen intermediates (ROIs) may have a role in the genotoxic effects of lead (Pb2+) and mercury (Hg2+), but there have not been any definitive studies demonstrating a causal relationship between the induction of RO
Publikováno v:
Environmental and molecular mutagenesis. 30(3)
Ascorbic acid (AA) has both antioxidant and prooxidant activities. However, there have not been any studies to elucidate the molecular mechanisms that determine whether AA functions as an anti- or a prooxidant during oxidative stress. The results of
Autor:
R, Kannan, G N, Bijur, S R, Mallery, F M, Beck, C L, Sabourin, S D, Jewell, D E, Schuller, G D, Stoner
Publikováno v:
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 82(1)
Proliferative verrucous leukoplakia is a unique type of oral leukoplakia that has a high risk of malignant transformation. The aim of this study was to examine the expression of transforming growth factor-alpha in proliferative verrucous leukoplakia,
Publikováno v:
Molecular carcinogenesis. 15(2)
Transforming growth factor-alpha (TGF-alpha) stimulates cell proliferation through interaction with its receptor, the epidermal growth factor receptor (EGFR), by activating its tyrosine kinase activities. The simultaneous overexpression of TGF-alpha
Granulocyte-macrophage colony stimulating factor gene expression and function during tumor promotion
Autor:
Carol L. K. Sabourin, G. N. Bijur, L. G. Boros, Fredika M. Robertson, A. E. Pellegrini, Tatiana M. Oberyszyn, Andrew S. Oberyszyn
Publikováno v:
Carcinogenesis. 15(5)
Although recent evidence suggests that granulocyte-macrophage colony stimulating factor (GM-CSF) plays a role in cutaneous inflammation induced by topical exposure of phorbol ester tumor promoters to murine epidermis, there is little information avai