In utero antiepileptic drug exposure: Fetal death and malformations

Autor: M. C. Wolff, Laura A. Kalayjian, Page B. Pennell, G. Mawer, Joyce Liporace, David W. Loring, J. C. Smith, Kimford J. Meador, Gus A. Baker, Richard H. Finnell

Publikováno v: Neurology. 67:407-412

Background: Pregnancy outcomes following in utero exposure to antiepileptic drugs (AEDs) are uncertain, limiting an evidenced-based approach. Objective: To determine if fetal outcomes vary as a function of different in utero AED exposures. Methods: T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be1c4b881c3f14a6a6776868ba39a705
https://doi.org/10.1212/01.wnl.0000227919.81208.b2

A placebo-controlled, double-blind cross-over trial of adjunctive one month remacemide hydrochloride treatment in patients with refractory epilepsy

Autor: Alan Richens, G. Mawer, P. Crawford, B. Harrison

Publikováno v: Seizure. 9(8):537-543

The efficacy, safety and pharmacokinetics of adjunctive remacemide hydrochloride, a novel, low-affinity non-competitive NMDA receptor channel blocker, were investigated in 28 adult patients with refractory epilepsy. This was a randomized double-blind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aca4e142c477fbd600e9129b87ba3cb

Autism spectrum disorders following in utero exposure to antiepileptic drugs

Autor: R L, Bromley, G, Mawer, J, Clayton-Smith, G A, Baker, Rebekah, Shallcross

Publikováno v: Bromley, R L, Mawer, G, Clayton-Smith, J & Baker, G A 2008, ' Autism spectrum disorders following in utero exposure to antiepileptic drugs ', Neurology, vol. 71, no. 23, pp. 1923-1924 . https://doi.org/10.1212/01.wnl.0000339399.64213.1a

There is evidence that in utero exposure to teratogenic substances such as thalidomide and alcohol may increase the risk of developing autism spectrum disorder (ASD)1 and that prenatal development may be a critical time. Animal model, case study, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4e94e821b1e9bf83b55ab6829fbb55
https://pure.manchester.ac.uk/ws/files/56692140/Autism_spectrum_disorders_following_in_utero_exposure_to_AEDs.docx

Fetal phenytoin exposure, hypoplastic nails, and jitteriness

Autor: S W D'Souza, D Donnai, G Mawer, I G Robertson

Publikováno v: Archives of disease in childhood. 66(3)

In a prospective study infants born to mothers with epilepsy (n = 61) were found to have an unexpectedly high incidence of congenital anomalies (26/61, 43%) and neonatal conditions (26/61, 43%) compared with controls (0/62, and 6/62, 10%, respectivel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01f7da75bb3a4c7db1f39f4b8620cd8
https://pubmed.ncbi.nlm.nih.gov/2025009

Medical students’ perspectives on the anatomy course at the University of Zimbabwe

Autor: R Siwela, G Mawera

Publikováno v: African Journal of Health Professions Education, Vol 9, Iss 4, Pp 176-179 (2017)

Background. Traditional academic-led anatomy teaching methods, such as didactic lectures and cadaver dissections, are on the decline, as more student-led teaching methods are being adopted.Objectives. To assess medical students’ perspectives o

Externí odkaz: https://doaj.org/article/59126baf5de941e9aea5bf5ee0cacd23