Zobrazeno 1 - 10
of 34
pro vyhledávání: '"G Mark Anderson"'
Autor:
Florence Schaffner, Naho Yokota, Tatiana Carneiro-Lobo, Maki Kitano, Michael Schaffer, G Mark Anderson, Barbara M Mueller, Charles T Esmon, Wolfram Ruf
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61071 (2013)
Several markers identify cancer stem cell-like populations, but little is known about the functional roles of stem cell surface receptors in tumor progression. Here, we show that the endothelial protein C receptor (EPCR), a stem cell marker in hemato
Externí odkaz:
https://doaj.org/article/da8ef9bf849d4e15a8b22dd9631721d9
Autor:
G. Mark Anderson, Matthew V. Lorenzi, Sylvie Laquerre, Ricardo M. Attar, Janine Schuurman, Paul W.H.I. Parren, Joost Neijssen, Pauline L. Martin, Sheng-Jiun Wu, Thomas Kelly, Peter Haytko, Randall J. Brezski, Keri Dorn, Leopoldo Luistro, Kristen Chevalier, Barbara S. Bushey, Mark L. Chiu, Sheri L. Moores
Non–small cell lung cancers (NSCLC) with activating EGFR mutations become resistant to tyrosine kinase inhibitors (TKI), often through second-site mutations in EGFR (T790M) and/or activation of the cMet pathway. We engineered a bispecific EGFR-cMet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08558d1a5bde3c55c0598591e7cde318
https://doi.org/10.1158/0008-5472.c.6507129
https://doi.org/10.1158/0008-5472.c.6507129
Autor:
G. Mark Anderson, Matthew V. Lorenzi, Sylvie Laquerre, Ricardo M. Attar, Janine Schuurman, Paul W.H.I. Parren, Joost Neijssen, Pauline L. Martin, Sheng-Jiun Wu, Thomas Kelly, Peter Haytko, Randall J. Brezski, Keri Dorn, Leopoldo Luistro, Kristen Chevalier, Barbara S. Bushey, Mark L. Chiu, Sheri L. Moores
Efficacy of JNJ-61186372 in H292-HGF Xenograft Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f90aafe25224f65576a2b1dcee502b4
https://doi.org/10.1158/0008-5472.22406625
https://doi.org/10.1158/0008-5472.22406625
Autor:
G. Mark Anderson, Matthew V. Lorenzi, Sylvie Laquerre, Ricardo M. Attar, Janine Schuurman, Paul W.H.I. Parren, Joost Neijssen, Pauline L. Martin, Sheng-Jiun Wu, Thomas Kelly, Peter Haytko, Randall J. Brezski, Keri Dorn, Leopoldo Luistro, Kristen Chevalier, Barbara S. Bushey, Mark L. Chiu, Sheri L. Moores
Antibody-Dependent Cellular Cytotoxicity Activity Profile of JNJ-61186372 in Human Lung Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a990a4dc585a73792e5238db3d3572
https://doi.org/10.1158/0008-5472.22406619
https://doi.org/10.1158/0008-5472.22406619
Publikováno v:
Delaware Journal of Public Health
Objective To develop a novel whole-blood epigenetic biomarker of immune system status, or EpiMarker, that would indicate whether a person with a recent COVID-19 diagnosis is at risk for severe symptoms including Acute Respiratory Distress Syndrome. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8ddffe3336f2d86a4d60c7f2ddf647a
https://pubmed.ncbi.nlm.nih.gov/34467104
https://pubmed.ncbi.nlm.nih.gov/34467104
Autor:
Thomas Valerius, Paul W. H. I. Parren, Janine Schuurman, Joost J. Neijssen, William R. Strohl, Kristen M. Chevalier, Luus Wiegman, Cardoso Rosa Maria Fernandes, Mark L. Chiu, Sheri Moores, G. Mark Anderson
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry, 296. ELSEVIER
Journal of Biological Chemistry, 296. ELSEVIER
A bispecific antibody (BsAb) targeting the epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor (MET) pathways represents a novel approach to overcome resistance to targeted therapies in patients with nonsmall cell lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca933b2c86ba6635402921bd327c1a34
https://hdl.handle.net/1887/3256851
https://hdl.handle.net/1887/3256851
Publikováno v:
Biochemical and Biophysical Research Communications. 494:700-705
Tissue factor (TF) is a transmembrane receptor for coagulation factor VII/VIIa and is frequently overexpressed by cancer cells. The TF/VIIa complex acts as the main initiator of the clotting cascade in blood and a trigger of intracellular signaling t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27902536f028499290fbaf56c8f4129c
https://doi.org/10.1016/j.bbrc.2017.10.139
https://doi.org/10.1016/j.bbrc.2017.10.139
Autor:
Yonghong Zhao, Alexey Teplyakov, Gary L. Gilliland, G. Mark Anderson, Thomas J. Malia, Susann Taudte, Bingyuan Wu, Galina Obmolova
Publikováno v:
Cellular Signalling. 36:139-144
Tissue factor (TF) initiates the extrinsic pathway of blood coagulation through sequential binding and activation of coagulation factors VII (FVII) and X (FX). In addition, through activation of G-protein-coupled protease activated receptors (PARs) T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69200b40effe4dcd6b3bc11f2afb5a27
https://doi.org/10.1016/j.cellsig.2017.05.004
https://doi.org/10.1016/j.cellsig.2017.05.004
Autor:
Nigel Mackman, Joanne Yu, Jeffrey I. Weitz, James P. Luyendyk, Janusz Rak, Chloe Milsom, G. Mark Anderson, George J. Broze, Linda May
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:1975-1981
Objective— The role of host-derived tissue factor (TF) in tumor growth, angiogenesis, and metastasis has hitherto been unclear and was investigated in this study. Methods and Results— We compared tumor growth, vascularity, and responses to cyclop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf4abd87addd3234825f6dd2e68068c
https://doi.org/10.1161/atvbaha.108.175083
https://doi.org/10.1161/atvbaha.108.175083
Autor:
Parul Doshi, Hillary Millar, Lillian Shahied-Arruda, Catherine Ferrante, Carol D. Manning, Celia Sharp, Qiming Chen, Francis L. McCabe, Marian T. Nakada, G. Mark Anderson
Publikováno v:
Clinical & Experimental Metastasis. 25:139-148
CNTO 95 is a fully human monoclonal antibody that recognizes alphav integrins. Previous studies have shown that CNTO 95 exhibits both anti-tumor and anti-angiogenic activities (Trikha M et al., Int J Cancer 110:326-335, 2004). In this study we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94772d462a81e07c0e85a42fd8a1a6b
https://doi.org/10.1007/s10585-007-9132-4
https://doi.org/10.1007/s10585-007-9132-4