Zobrazeno 1 - 10
of 479
pro vyhledávání: '"G Manz"'
Autor:
Christian Pellegrino, Nicholas Favalli, Laura Volta, Ramon Benz, Sara Puglioli, Gabriele Bassi, Kathrin Zitzmann, Christoph Josef Auernhammer, Svenja Nölting, Chiara F. Magnani, Dario Neri, Felix Beuschlein, Markus G. Manz
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Somatostatin receptor type 2 (SSTR2) is one of the five subtypes of somatostatin receptors and is overexpressed on the surface of most gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs), pituitary tumors, paraganglioma, and meningioma, as well
Externí odkaz:
https://doaj.org/article/3ef1e2ed9ab14eb1a9a52aba835a4e4d
Autor:
Laura Volta, Renier Myburgh, Mara Hofstetter, Christian Koch, Jonathan D. Kiefer, Celeste Gobbi, Francesco Manfredi, Kathrin Zimmermann, Philipp Kaufmann, Serena Fazio, Christian Pellegrino, Norman F. Russkamp, Danielle Villars, Mattia Matasci, Monique Maurer, Jan Mueller, Florin Schneiter, Paul Büschl, Niclas Harrer, Jacqueline Mock, Stefan Balabanov, César Nombela‐Arrieta, Timm Schroeder, Dario Neri, Markus G. Manz
Publikováno v:
HemaSphere, Vol 8, Iss 11, Pp n/a-n/a (2024)
Abstract Acute myeloid leukemia (AML) derives from hematopoietic stem and progenitor cells (HSPCs). To date, no AML‐exclusive, non‐HSPC‐expressed cell‐surface target molecules for AML selective immunotherapy have been identified. Therefore, t
Externí odkaz:
https://doaj.org/article/f01601fd49bb490c81391fc86db051b9
Autor:
Katerina Bakunina, Hein Putter, Jurjen Versluis, Eva A. S. Koster, Bronno van derHolt, Markus G. Manz, Dimitri A. Breems, Bjorn T. Gjertsen, Jacqueline Cloos, Peter J. M. Valk, Jakob Passweg, Thomas Pabst, Gert J. Ossenkoppele, Bob Löwenberg, Jan J. Cornelissen, Liesbeth C. deWreede
Publikováno v:
Cancer Medicine, Vol 11, Iss 3, Pp 630-640 (2022)
Abstract Clofarabine is an active antileukemic drug for subgroups of patients with acute myeloid leukemia (AML). Multi‐state models can provide additional insights to supplement the original intention‐to‐treat analysis of randomized controlled
Externí odkaz:
https://doaj.org/article/efddc38d4b904e3199e4f5412bc60ca2
Autor:
Nadia El Khawanky, Amy Hughes, Wenbo Yu, Renier Myburgh, Tony Matschulla, Sanaz Taromi, Konrad Aumann, Jade Clarson, Janaki Manoja Vinnakota, Khalid Shoumariyeh, Cornelius Miething, Angel F. Lopez, Michael P. Brown, Justus Duyster, Lutz Hein, Markus G. Manz, Timothy P. Hughes, Deborah L. White, Agnes S. M. Yong, Robert Zeiser
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The success of CAR-T cells for treating acute myeloid leukaemia (AML) is hampered by toxicity to normal cells and low CAR-T cell persistence. Here, the authors show that the demethylating compound 5′-Azacitdine increases anti-CD123 CAR-T cell cytot
Externí odkaz:
https://doaj.org/article/fe5a9441efac4b52a10770a66f35954d
Autor:
Irene A. Abela, Chloé Pasin, Magdalena Schwarzmüller, Selina Epp, Michèle E. Sickmann, Merle M. Schanz, Peter Rusert, Jacqueline Weber, Stefan Schmutz, Annette Audigé, Liridona Maliqi, Annika Hunziker, Maria C. Hesselman, Cyrille R. Niklaus, Jochen Gottschalk, Eméry Schindler, Alexander Wepf, Urs Karrer, Aline Wolfensberger, Silvana K. Rampini, Patrick M. Meyer Sauteur, Christoph Berger, Michael Huber, Jürg Böni, Dominique L. Braun, Maddalena Marconato, Markus G. Manz, Beat M. Frey, Huldrych F. Günthard, Roger D. Kouyos, Alexandra Trkola
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
How the immune responses induced by SARS-CoV-2 and human coronavirus (hCoV) crosstalk is still unclear. Here the authors profile the humoral responses of prepandemic and SARS-CoV-2-infected donors to find that higher hCoV antibody titers are associat
Externí odkaz:
https://doaj.org/article/9ae1432b592c419493eac058f90406ee
Autor:
Jesse M. Tettero, Waleed K. W. Al-Badri, Lok Lam Ngai, Costa Bachas, Dimitri A. Breems, Catharina H. M. J. van Elssen, Thomas Fischer, Bjorn T. Gjertsen, Gwendolyn N. Y. van Gorkom, Patrycja Gradowska, Marjolein J. E. Greuter, Laimonas Griskevicius, Gunnar Juliusson, Johan Maertens, Markus G. Manz, Thomas Pabst, Jakob Passweg, Kimmo Porkka, Bob Löwenberg, Gert J. Ossenkoppele, Jeroen J. W. M. Janssen, Jacqueline Cloos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Measurable residual disease (MRD) measured using multiparameter flow-cytometry (MFC) has proven to be an important prognostic biomarker in acute myeloid leukemia (AML). In addition, MRD is increasingly used to guide consolidation treatment towards a
Externí odkaz:
https://doaj.org/article/56f5490a20524932aafd0bb2d3219e7c
Autor:
Fabienne Meier-Abt, Witold E. Wolski, Ge Tan, Sandra Kummer, Sabine Amon, Markus G. Manz, Ruedi Aebersold, Alexandre P. A. Theocharides
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 2, Pp 1-6 (2021)
Externí odkaz:
https://doaj.org/article/1143b56ea9694aca9fea29e2f7ce966e
Autor:
Wiebke Rösler, Andrea Bink, Marina Bissig, Lukas Imbach, Ewerton Marques Maggio, Markus G. Manz, Thomas Müller, Patrick Roth, Elisabeth Rushing, Corinne Widmer, Thorsten Zenz, Seraina von Moos, Antonia M. S. Müller
Publikováno v:
HemaSphere, Vol 6, Iss 7, p e733 (2022)
Externí odkaz:
https://doaj.org/article/e738f2730c664befb16db39f17aa04bc
Autor:
Sebastian Stolz, Marco Roncador, Wiebke Rösler, Thorsten Zenz, Markus G. Manz, Antonia M.S. Müller, Corinne C. Widmer
Publikováno v:
Swiss Medical Weekly, Vol 152, Iss 2526 (2022)
AIM OF THE STUDY: Chimeric antigen receptor T (CAR-T) cells are a powerful form of immune-cell therapy for patients with relapsed/refractory B-cell lymphoma and acute B lymphoblastic leukaemia. CAR-T cells have been commercially available in Switzerl
Externí odkaz:
https://doaj.org/article/47fa44e394e64f378a4571b47cd5f13d
Autor:
Maddalena Marconato, Irene A. Abela, Anthony Hauser, Magdalena Schwarzmüller, Rheliana Katzensteiner, Dominique L. Braun, Selina Epp, Annette Audigé, Jacqueline Weber, Peter Rusert, Eméry Schindler, Chloé Pasin, Emily West, Jürg Böni, Verena Kufner, Michael Huber, Maryam Zaheri, Stefan Schmutz, Beat M. Frey, Roger D. Kouyos, Huldrych F. Günthard, Markus G. Manz, Alexandra Trkola
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)
BACKGROUND Neutralizing antibodies are considered a key correlate of protection by current SARS-CoV-2 vaccines. The manner in which human infections respond to therapeutic SARS-CoV-2 antibodies, including convalescent plasma therapy, remains to be fu
Externí odkaz:
https://doaj.org/article/297d34da9c8446cd95b66a14cc84d8ad