Zobrazeno 1 - 10
of 20
pro vyhledávání: '"G M Reynolds"'
Autor:
Edwardo G. M. Reynolds, Thomas Lopdell, Yu Wang, Kathryn M. Tiplady, Chad S. Harland, Thomas J. J. Johnson, Catherine Neeley, Katie Carnie, Richard G. Sherlock, Christine Couldrey, Stephen R. Davis, Bevin L. Harris, Richard J. Spelman, Dorian J. Garrick, Mathew D. Littlejohn
Publikováno v:
Genetics Selection Evolution, Vol 54, Iss 1, Pp 1-16 (2022)
Abstract Background Deleterious recessive conditions have been primarily studied in the context of Mendelian diseases. Recently, several deleterious recessive mutations with large effects were discovered via non-additive genome-wide association studi
Externí odkaz:
https://doaj.org/article/c6d74fe902814b03a9b570eab1034eda
Autor:
Edwardo G M, Reynolds, Catherine, Neeley, Thomas J, Lopdell, Michael, Keehan, Keren, Dittmer, Chad S, Harland, Christine, Couldrey, Thomas J J, Johnson, Kathryn, Tiplady, Gemma, Worth, Mark, Walker, Stephen R, Davis, Richard G, Sherlock, Katie, Carnie, Bevin L, Harris, Carole, Charlier, Michel, Georges, Richard J, Spelman, Dorian J, Garrick, Mathew D, Littlejohn
Publikováno v:
Nature genetics. 53(7)
Mammalian species carry ~100 loss-of-function variants per individual
Autor:
D. Read, R. H. Vassar, R.T. Parmley, J. vanden Beukel, K. Shaul, G. M. Reynolds, D. St. Clair, W. Reeve
Publikováno v:
Advances in Space Research. 25:1193-1197
Gravity Probe B is an extremely precise space experiment which will test Einstein's General Theory of Relativity. The cryogenic probe, dewar and spacecraft provide the stable platform and the rigorous environmental conditions necessary for the scienc
Publikováno v:
Molecular Pathology. 49:M273-M277
Aims-To overcome the problems associated with proteolytic pretreatment of tissue sections for the detection of apoptosis.Methods-Formalin fixed, paraffin wax embedded tissue sections of reactive lymph nodes and biopsy specimens of Burkitt lymphoma we
Publikováno v:
Cytopathology. 7:132-135
Publikováno v:
Nephrology Dialysis Transplantation. 10:2212-2218
Background. Proliferating cells can be detected in histological material in various ways. This investigation was to study the feasibility and usefulness of application of proliferation markers to routine renal biopsy specimens. Methods. One hundred a
Publikováno v:
Molecular Pathology. 48:M105-M108
Aim —To examine the expression of CD40 and B7 (CD80) antigens and the CD40 ligand in Hodgkin9s disease. Methods —Antigen and ligand expression was studied in 17 cases of Hodgkin9s disease using immunohistochemistry. The study included 11 cases of
Publikováno v:
Cytopathology. 5:345-358
Microwave oven antigen retrieval has been developed to extend the range of antibodies that can be used upon sections of fixed and processed tissue. It has the additional advantages of improving immunostain intensity and reducing background positivity
Publikováno v:
International journal of cancer. 88(6)
Nasopharyngeal carcinoma (NPC) is an aggressive tumour of multifactorial aetiology that, although rare in most parts of the world, poses a significant mortality problem in its high incidence area of Southern China. Improved therapies are an urgent re
Autor:
Simon R. Carter, R. J. Grimer, Paul Pynsent, Roger M. Tillman, G M Reynolds, Adesegun Abudu, D. C. Mangham
Publikováno v:
British Journal of Cancer
Biopsy tissues of 52 patients with Ewing's sarcoma of bone treated between 1983 and 1993 were examined immunohistochemically to determine the significance of p53 protein in diagnosis and prognosis of Ewing's sarcoma. Mean age at diagnosis was 17 year