Zobrazeno 1 - 10
of 25
pro vyhledávání: '"G M Fless"'
Publikováno v:
Journal of Lipid Research, Vol 31, Iss 5, Pp 909-918 (1990)
The protein moiety of Lp[a] consisting of apoB and apo[a] covalently linked to each other, once freed of lipids by delipidation at pH 8.0 with mixtures of diethyl ether and ethanol, is freely water-soluble at pH values above 6.4. This is in contrast
Externí odkaz:
https://doaj.org/article/77ec44d6fa84490995193fd661417ef3
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 3, Pp 288-297 (1985)
Prostacyclin (PGI2) production by bovine aortic or human umbilical vein endothelial cells increased when either human high density lipoproteins3 (HDL3) or low density lipoproteins (LDL) were added to a serum-free culture medium. At low concentrations
Externí odkaz:
https://doaj.org/article/3726f8876d1745b3acbbef51021b366c
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 10, Pp 1224-1229 (1985)
An easy method was developed for the rapid and selective isolation of apo(a) from human plasma Lp(a). This procedure was applied to a ''low density'' Lp(a) subspecies (usually found in the density interval 1.050 to 1.070 g/ml) from a single individua
Externí odkaz:
https://doaj.org/article/49e0e96a80844ce4aad0feb316b8310e
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 5, Pp 651-662 (1989)
Based on our findings that rabbit antisera raised against human Lp[a] or apo[a] have the potential to cross-react with plasminogen, and in some cases have nearly equal affinities for plasminogen and Lp[a], we have developed an assay for plasma Lp[a]
Externí odkaz:
https://doaj.org/article/36685409bbbb44889047c765c3963ca6
Autor:
A M Scanu, A Khalil, L Neven, M Tidore, G Dawson, D Pfaffinger, E Jackson, K D Carey, H C McGill, G M Fless
Publikováno v:
Journal of Lipid Research, Vol 29, Iss 12, Pp 1671-1681 (1988)
A family of rhesus monkeys comprising a sire, a dam, and four male offspring were fed a cholesterol-free Purina Chow diet for several months. The sire, 431-J, and two of the offspring, B-8204 and B-8806, had persistent plasma cholesterol levels in th
Externí odkaz:
https://doaj.org/article/9bf084ef105b495f859f94fa16094361
Publikováno v:
Journal of Biological Chemistry. 268:8569-8573
Lipoprotein(a) levels in the plasma are strongly correlated with atherosclerotic coronary artery disease. Although the mechanism of this effect is not known, the interaction of lipoprotein(a) with macrophages may be important. Previous work has shown
Publikováno v:
Arteriosclerosis: An Official Journal of the American Heart Association, Inc.. 10:240-245
Lipoprotein(a) (Lp[a]) is a complex plasma lipoprotein in which apolipoprotein (apo) B-100 is covalently linked by a disulfide bridge to a unique apolipoprotein, apo(a). The cDNA of apo(a) has recently been isolated and sequenced, and a remarkable ho
Autor:
G M, Fless, E W, Kirk, O, Klezovitch, J Y, Santiago, C, Edelstein, J, Hoover-Plow, A M, Scanu
Publikováno v:
Journal of lipid research. 40(4)
In vitro hydrolysis of human lipoprotein[a] (Lp[a]) by phospholipase A2 (PLA2) decreased the phosphatidylcholine (PC) content by 85%, but increased nonesterified fatty acids 3.2-fold and lysoPC 12.9-fold. PLA2-treated Lp[a] had a decreased molecular
Autor:
G M, Fless, M L, Snyder
Publikováno v:
Methods in enzymology. 263
Autor:
L A, Miles, G M, Fless, A M, Scanu, P, Baynham, M T, Sebald, P, Skocir, L K, Curtiss, E G, Levin, J L, Hoover-Plow, E F, Plow
Publikováno v:
Thrombosis and haemostasis. 73(3)
Lp(a) competes with plasminogen for binding to cells but it is not known whether this competition is due to the ability of Lp(a) to interact directly with plasminogen receptors. In the present study, we demonstrate that Lp(a) can interact directly wi