Zobrazeno 1 - 10
of 161
pro vyhledávání: '"G M, Verjans"'
Autor:
Eleanor M. Marshall, Ahmad S. Rashidi, Michiel van Gent, Barry Rockx, Georges M. G. M. Verjans
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Usutu (USUV), West Nile (WNV), and Zika virus (ZIKV) are neurotropic arthropod-borne viruses (arboviruses) that cause severe neurological disease in humans. However, USUV-associated neurological disease is rare, suggesting a block in entry t
Externí odkaz:
https://doaj.org/article/72346cc4c62d4b7f9634f94acb82a69a
Autor:
Ahmad S. Rashidi, Diana N. Tran, Caithlin R. Peelen, Michiel van Gent, Werner J. D. Ouwendijk, Georges M. G. M. Verjans
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Background Herpes simplex virus (HSV) encephalitis (HSE) is a serious and potentially life-threatening disease, affecting both adults and newborns. Progress in understanding the virus and host factors involved in neonatal HSE has been hamper
Externí odkaz:
https://doaj.org/article/b88ea03d1b0f4500a530e2c9cda88775
Autor:
Michiel van Gent, Werner J. D. Ouwendijk, Victoria L. Campbell, Kerry J. Laing, Georges M. G. M. Verjans, David M. Koelle
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Trigeminal ganglia (TG) neurons are an important site of lifelong latent varicella-zoster virus (VZV) infection. Although VZV-specific T-cells are considered pivotal to control virus reactivation, their protective role at the site
Externí odkaz:
https://doaj.org/article/14716dfbf27c4c7298ae00f3d4233611
Autor:
Tabitha E. Hoornweg, Gert-Jan Godeke, Marieke N. Hoogerwerf, Puck B. van Kasteren, Ankje de Vries, Hein Sprong, Georges M. G. M. Verjans, Debby van Riel, Johan H. J. Reimerink, Barry Rockx, Chantal B. E. M. Reusken
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Tick-borne encephalitis virus (TBEV) may cause tick-borne encephalitis (TBE), a potential life-threatening infection of the central nervous system in humans. Phylogenetically, TBEVs can be subdivided into three main subtypes, which differ in
Externí odkaz:
https://doaj.org/article/145dec037d5c4db79184c779c3e0381d
Autor:
Kerry J. Laing, Werner J. D. Ouwendijk, Victoria L. Campbell, Christopher L. McClurkan, Shahin Mortazavi, Michael Elder Waters, Maxwell P. Krist, Richard Tu, Nhi Nguyen, Krithi Basu, Congrong Miao, D. Scott Schmid, Christine Johnston, Georges M. G. M. Verjans, David M. Koelle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
T cells are considered important for controlling skin infections. Here, the authors report that varicella-zoster virus-specific T cells preferentially persist as tissue-resident-memory T cells in rash-involved skin after recovery from zoster.
Externí odkaz:
https://doaj.org/article/a1fabd9c8f51401c94e1954711560ae7
Autor:
Johanna L. Heinz, Sigrid M. A. Swagemakers, Joanna von Hofsten, Marie Helleberg, Michelle M. Thomsen, Kerstin De Keukeleere, Joke H. de Boer, Tomas Ilginis, Georges M. G. M. Verjans, Peter M. van Hagen, Peter J. van der Spek, Trine H. Mogensen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
PurposeHerpes simplex virus (HSV) and varicella-zoster virus (VZV) are neurotropic human alphaherpesviruses endemic worldwide. Upon primary infection, both viruses establish lifelong latency in neurons and reactivate intermittently to cause a variety
Externí odkaz:
https://doaj.org/article/2755a6e1e135421ea6420d24946ac46e
Autor:
Peter-Paul A. Unger, Anna E. Oja, Tamana Khemai-Mehraban, Werner J. D. Ouwendijk, Pleun Hombrink, Georges M. G. M. Verjans
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Trigeminal ganglia (TG) neurons are the main site of lifelong latent herpes simplex virus type 1 (HSV-1) infection. T-cells in ganglia contribute to long-term control of latent HSV-1 infection, but it is unclear whether these cell
Externí odkaz:
https://doaj.org/article/7cd9a7aa026e4dcdb0d7747d810f3bd4
Autor:
S. Reshwan K. Malahe, Jeroen J. A. van Kampen, Olivier C. Manintveld, Rogier A. S. Hoek, Caroline M. den Hoed, Carla C. Baan, Marcia M. L. Kho, Georges M. G. M. Verjans
Publikováno v:
Viruses, Vol 15, Iss 7, p 1595 (2023)
Solid organ transplant recipients (SOTRs) are at high risk of human herpesvirus (HHV)-related morbidity and mortality due to the use of immunosuppressive therapy. We aim to increase awareness and understanding of HHV disease burden in SOTRs by provid
Externí odkaz:
https://doaj.org/article/91d7a301a5834d7db4ecdb3972ab81be
Autor:
Werner J. D. Ouwendijk, Daniel P. Depledge, Labchan Rajbhandari, Tihana Lenac Rovis, Stipan Jonjic, Judith Breuer, Arun Venkatesan, Georges M. G. M. Verjans, Tomohiko Sadaoka
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Varicella-zoster virus (VZV) establishes lifelong neuronal latency in humans. Here, Ouwendijk and Depledge et al. identify a fusion transcript, VLT-ORF63, which is expressed during lytic and latent infection, and demonstrate a role for the translated
Externí odkaz:
https://doaj.org/article/77e9fbb4bab3420d9944cbe543a9206c
Autor:
Shirley E Braspenning, Georges M G M Verjans, Tamana Mehraban, Ilhem Messaoudi, Daniel P Depledge, Werner J D Ouwendijk
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010084 (2021)
Primary infection with varicella-zoster virus (VZV) causes varicella and the establishment of lifelong latency in sensory ganglion neurons. In one-third of infected individuals VZV reactivates from latency to cause herpes zoster, often complicated by
Externí odkaz:
https://doaj.org/article/86449d0da5794dd39ce9a7f6db65290f