Zobrazeno 1 - 10
of 26
pro vyhledávání: '"G M, Stancel"'
Autor:
R B, Dickson, G M, Stancel
Publikováno v:
Journal of the National Cancer Institute. Monographs. (27)
The role of estrogens in breast and other cancers has been extensively investigated for many years, and historically most of these studies have focused on the hormonal regulation of cell proliferation. The most recent work in this area has focused on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ae8845a62dc3a1a35c3f20cfb9fa758
https://pubmed.ncbi.nlm.nih.gov/10963625
https://pubmed.ncbi.nlm.nih.gov/10963625
Publikováno v:
Cancer research. 60(12)
Vascular endothelial growth factor (VEGF) is a potent stimulator of angiogenesis and a prognostic factor for many tumors including those of endocrine-responsive tissues such as the breast and uterus. We and others have previously shown that VEGF is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac49f8b5dd398fa777eaf3f979e0043b
https://pubmed.ncbi.nlm.nih.gov/10866309
https://pubmed.ncbi.nlm.nih.gov/10866309
Autor:
S M, Hyder, G M, Stancel
Publikováno v:
Histology and histopathology. 15(1)
Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis. In adults, angiogenesis is an infrequent event in the normal tissue except in the female reproductive tract where angiogenesis occurs frequently during the cyclical repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::672812698fcab113481c0c7a9715109e
https://pubmed.ncbi.nlm.nih.gov/10668221
https://pubmed.ncbi.nlm.nih.gov/10668221
Publikováno v:
Cancer research. 59(2)
The pure antiestrogen ICI 182,780 binds to the estrogen receptor with high affinity and is currently in clinical trials for the treatment of human breast cancer. We now show for the first time that ICI 182,780 also exhibits potent antiprogestin activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4095e28b9750a63eeac7e27fe6d624bc
https://pubmed.ncbi.nlm.nih.gov/9927049
https://pubmed.ncbi.nlm.nih.gov/9927049
Publikováno v:
Molecular biology reports. 25(3)
We previously identified an estrogen response element in the 3'-flanking region of the c-fos protooncogene [1, 2]. This element, GGTCAnnnCAGCC, has one half-site identical to that of the consensus ERE (GGTCAnnnTGACC) but only limited homology to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::712a76e57ceacd7d6b4d2b55eec9e887
https://pubmed.ncbi.nlm.nih.gov/9700055
https://pubmed.ncbi.nlm.nih.gov/9700055
Publikováno v:
Biology of reproduction. 58(3)
Protein kinase C (PKC) is a key regulatory enzyme in the control of growth and differentiated function in many cell types. Recently it has become clear that cross talk occurs between PKC and steroid hormone-activated signaling pathways. In this work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2189942f30d979c76e024e4a8e2b8a7
https://pubmed.ncbi.nlm.nih.gov/9510966
https://pubmed.ncbi.nlm.nih.gov/9510966
Publikováno v:
Cancer research. 58(3)
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor associated with the degree of vascularity, progression, and metastasis of breast cancer, and cases of this disease with increased vascular density have a poor prognosis. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c77e4cbe0c6d491c1c33f6b5b3571992
https://pubmed.ncbi.nlm.nih.gov/9458078
https://pubmed.ncbi.nlm.nih.gov/9458078
Publikováno v:
Cancer research. 57(13)
Estrogen-stimulated cell proliferation is thought to be mediated by the induction of growth-regulatory factors. Abnormal regulation of such factors may be associated with tumorigenesis. Two such factors, vascular endothelial growth factor and c-fos,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b4aa1171eaae2cb2c405efe51e8df8d
https://pubmed.ncbi.nlm.nih.gov/9205050
https://pubmed.ncbi.nlm.nih.gov/9205050
Publikováno v:
Cancer research. 56(17)
Vascular endothelial growth factor (VEGF) is an endothelial-specific mitogen with potent angiogenic activity. Because vascular growth accompanies normal endometrial regeneration and may also be involved in uterine tumor growth, we studied VEGF regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b28dac97270de18f385e3c2dea3b6861
https://pubmed.ncbi.nlm.nih.gov/8752163
https://pubmed.ncbi.nlm.nih.gov/8752163
Publikováno v:
Molecular pharmacology. 43(5)
Estrogens regulate the in vivo expression of the c-fos proto-oncogene in rat uterus, and this regulation appears to occur at the transcriptional level. This system thus provides the ability to study the in vivo effects of antiestrogens on specific ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b97c808163f3a8a569f01a6305de4106
https://pubmed.ncbi.nlm.nih.gov/8502228
https://pubmed.ncbi.nlm.nih.gov/8502228