Zobrazeno 1 - 10
of 10
pro vyhledávání: '"G M, Keller"'
Autor:
C, Voelkel-Johnson, D J, Voeks, N M, Greenberg, R, Barrios, F, Maggouta, D T, Kurtz, D A, Schwartz, G M, Keller, T, Papenbrock, G A, Clawson, J S, Norris
Publikováno v:
Carcinogenesis. 21(8)
To develop animal models that represent the broad spectrum of human prostate cancer, we created transgenic mice with targeted prostate-specific expression of two genes (ECO:RI and c-fos) implicated in the induction of genomic instability. Expression
Autor:
T, Ishizuka, K, Chayama, K, Takeda, E, Hamelmann, N, Terada, G M, Keller, G L, Johnson, E W, Gelfand
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(4)
Aggregation of high affinity FcR for IgE (Fc epsilon RI) on mast cells activates intracellular signal transduction pathways, including the activation of protein tyrosine kinases, phosphatidylinositol 3-kinase (PI3-kinase), and protein kinase C. Bindi
Autor:
T, Ishizuka, H, Kawasome, N, Terada, K, Takeda, P, Gerwins, G M, Keller, G L, Johnson, E W, Gelfand
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(7)
Mast cells express the receptor tyrosine kinase kit/stem cell factor receptor (SCFR) which is encoded by the proto-oncogene c-kit. Ligation of SCFR induces its dimerization and activation of its intrinsic tyrosine kinase activity leading to activatio
Publikováno v:
Journal of child neurology. 12(6)
Other than hamartomatous enlargement of the cerebellum as in Lhermitte-Duclos syndrome, diffuse enlargement of the cerebellum is not clearly described. We report four patients (ages 9 months to 2 years) with diffusely enlarged cerebelli as identified
Autor:
C R Jefcoate, G M Keller
Publikováno v:
Journal of Biological Chemistry. 259:13770-13776
Metabolism of benzo(a)pyrene (BP) and 7,8-dihydrodiol by 3-methylcholanthrene (MC)-induced rat liver microsomes are both subject to severe inhibition by primary metabolites of BP, which was analyzed by determining individual inhibition constants for
Publikováno v:
Molecular pharmacology. 22(2)
Autor:
G M, Keller, C R, Jefcoate
Publikováno v:
The Journal of biological chemistry. 259(22)
Metabolism of benzo(a)pyrene (BP) and 7,8-dihydrodiol by 3-methylcholanthrene (MC)-induced rat liver microsomes are both subject to severe inhibition by primary metabolites of BP, which was analyzed by determining individual inhibition constants for
Autor:
G M, Keller, C R, Jefcoate
Publikováno v:
Molecular pharmacology. 23(3)
Inclusion of calf thymus DNA during microsomal benzo[a]pyrene (BP) metabolism increases product formation by decreasing the accessibility of microsomal enzymes to inhibitory BP quinones. The relief of product inhibition of BP metabolism, the stimulat
Autor:
G M, Keller, R A, Phillips
Publikováno v:
Experimental hematology. 12(11)
Although phenotypically similar, the cellular defects in congenitally anemic mice of genotype W/Wv and S1/S1d are quite different. W/Wv mice have defective hemopoietic stem cells; in contrast, S1/S1d mice have normal stem cells, but their hemopoietic
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 132(4)
Cells from mice with severe combined immunodeficiency disease (SCID) were tested in assays that measure myeloid and lymphoid function. Results showed that C.B-17 scid and their normal counterparts (C.B-17) have similar levels of spleen colony-forming