Emasculating healers. Medical castration practices in Greco-Roman antiquity*

Autor: Jacqueline G. M. König

Publikováno v: Journal of Ancient History. 9:221-237

In the course of the human past the elimination of the testicles of boys and men – what we call castration – has taken place for a variety of reasons. Many times it was meant to deliberately hurt people. It is and was also performed, though, as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::174353b0fdd393f7bceeca7b708e8065
https://doi.org/10.1515/jah-2021-0002

Condensation Domain Editing of the FR900359 Assembly Line Yields a Novel Analog Amenable to Late-Stage Functionalization.

Autor: Pistorius D; Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Richard E; Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Buntin K; Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Dresen K; Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Wollbrett S; Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Weber E; Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Haberkorn A; Oncology Disease Area, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Manchado E; Oncology Disease Area, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland., Petersen F; Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, Novartis Campus, 4056, Basel, Switzerland.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Nov 04; Vol. 25 (21), pp. e202400491. Date of Electronic Publication: 2024 Sep 12.

Sensing of Liver‐Derived Nicotinamide by Intestinal Group 2 Innate Lymphoid Cells Links Liver Cirrhosis and Ulcerative Colitis Susceptibility.

Autor: Shen, Jing^1,2 (AUTHOR), Li, Zhen¹ (AUTHOR), Liu, Xiaoyu² (AUTHOR), Zheng, Mengqi^1,3 (AUTHOR), Zhang, Peng⁴ (AUTHOR), Chen, Yatai² (AUTHOR), Tian, Qiuheng² (AUTHOR), Tian, Wenyu² (AUTHOR), Kou, Guanjun¹ (AUTHOR), Cui, Yanyan² (AUTHOR), Xu, Bowen⁴ (AUTHOR), Zhai, Yunjiao² (AUTHOR), Li, Weijia^1,3 (AUTHOR), Guo, Xiaohuan^5,6 (AUTHOR), Qiu, Ju⁷ (AUTHOR), Li, Chunyang⁸ (AUTHOR), He, Ran⁹ (AUTHOR), Li, Lixiang^1,3 (AUTHOR), Ma, Chunhong^8,10 (AUTHOR), Li, Yanqing^1,3 (AUTHOR)

Publikováno v: Advanced Science. 10/16/2024, Vol. 11 Issue 38, p1-15. 15p.

Antiplasmodial and cytotoxic metabolites from the Maltese sponge Agelas oroides

Autor: G M, König, A D, Wright, A, Linden

Publikováno v: Planta medica. 64(5)

From a Maltese sample of the marine sponge Agelas oroides, five compounds: oroidin (1), 2-cyano-4,5-dibromopyrrole (2), 4,5-dibromopyrrole-2-carboxylic acid (3), 4,5-dibromopyrrole-2-carboxylic acid methyl ester (4), and 4 alpha-methyl-5 alpha-choles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a19b4052e92d3054ac7023476b52e8a9
https://pubmed.ncbi.nlm.nih.gov/9690346

In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G q -Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont.

Autor: Hashimoto T; National Institute of Advanced Industrial Science and Technology, 2-4-7 Aomi, Koto-ku, Tokyo, 135-0064, Japan.; National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan., Suenaga H; National Institute of Advanced Industrial Science and Technology, 2-4-7 Aomi, Koto-ku, Tokyo, 135-0064, Japan., Amagai K; Natural Product Biosynthesis Research Unit, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan., Hashimoto J; Japan Biological Informatics Consortium, 2-4-7 Aomi, Koto-ku, Tokyo, 135-0064, Japan., Kozone I; Japan Biological Informatics Consortium, 2-4-7 Aomi, Koto-ku, Tokyo, 135-0064, Japan., Takahashi S; Natural Product Biosynthesis Research Unit, RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan., Shin-Ya K; National Institute of Advanced Industrial Science and Technology, 2-4-7 Aomi, Koto-ku, Tokyo, 135-0064, Japan.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Mar 04; Vol. 63 (10), pp. e202317805. Date of Electronic Publication: 2024 Feb 02.