Zobrazeno 1 - 10
of 85
pro vyhledávání: '"G M, Brodeur"'
Autor:
S, Goto, S, Umehara, R B, Gerbing, D O, Stram, G M, Brodeur, R C, Seeger, J N, Lukens, K K, Matthay, H, Shimada
Publikováno v:
Cancer. 92(10)
The International Neuroblastoma Pathology Classification (International Classification), which was established in 1999, is significant prognostically and is relevant biologically for the evaluation and analysis of patients with neuroblastic tumors (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99e9b136bdf61bbf9a926ceb92aa3959
https://pubmed.ncbi.nlm.nih.gov/11745206
https://pubmed.ncbi.nlm.nih.gov/11745206
Autor:
A E, Evans, K D, Kisselbach, X, Liu, A, Eggert, N, Ikegaki, A M, Camoratto, C, Dionne, G M, Brodeur
Publikováno v:
Medical and pediatric oncology. 36(1)
The compound CEP-751 (KT-6587), a potent and selective inhibitor of the Trk family of tyrosine kinases, has been shown to inhibit the growth of human neuroblastoma (NB) xenografts in nude mice [1].To address its mechanism of action, we studied SY5Y,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee45c4f76a5a109944c80c57e229945d
https://pubmed.ncbi.nlm.nih.gov/11464878
https://pubmed.ncbi.nlm.nih.gov/11464878
Autor:
J M, Maris, C, Guo, P S, White, M D, Hogarty, P M, Thompson, D O, Stram, R, Gerbing, K K, Matthay, R C, Seeger, G M, Brodeur
Publikováno v:
Medical and pediatric oncology. 36(1)
Neuroblastoma tumorigenesis may involve the differential inactivation of multiple tumor suppressor genes. Recent data have suggested that a neuroblastoma suppressor gene may be located on the long arm of chromosome 11 (11q).We therefore analyzed 295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59cbede81ec57448fdd1871819f4eac9
https://pubmed.ncbi.nlm.nih.gov/11464895
https://pubmed.ncbi.nlm.nih.gov/11464895
Publikováno v:
Medical and pediatric oncology. 36(1)
Deletion of the distal short arm of chromosome 1 occurs in 25-35% of primary neuroblastomas, and a putative tumor suppressor gene has been mapped to a consensus region of deletion at 1p36.2-36.3. Indirect evidence suggests the presence of an imprinte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d7c902a3a71295bfd7f3ee6b381c4a0
https://pubmed.ncbi.nlm.nih.gov/11464906
https://pubmed.ncbi.nlm.nih.gov/11464906
Autor:
P M, Thompson, B A, Seifried, S K, Kyemba, S J, Jensen, C, Guo, J M, Maris, G M, Brodeur, D O, Stram, R C, Seeger, R, Gerbing, K K, Matthay, T C, Matise, P S, White
Publikováno v:
Medical and pediatric oncology. 36(1)
Neuroblastoma is a genetically heterogeneous disease, with subsets of tumors demonstrating rearrangements of several genomic regions. Preliminary studies from several groups have identified loss of heterozygosity (LOH) for the long arm of chromosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47b78b20cf143a792d304727f4b62109
https://pubmed.ncbi.nlm.nih.gov/11464899
https://pubmed.ncbi.nlm.nih.gov/11464899
Publikováno v:
Medical and pediatric oncology. 36(1)
The EPH family is the largest subfamily of receptor protein-tyrosine kinases, consisting of EPHA and EPHB subgroups. Ligands of EPH family receptors are called ephrins, which include ephrin-A and ephrin-B subgroups. We recently found that transcripts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8eba2221fef8bd8e1aae3a12d7e390ec
https://pubmed.ncbi.nlm.nih.gov/11464911
https://pubmed.ncbi.nlm.nih.gov/11464911
Autor:
P S, White, P M, Thompson, B A, Seifried, E P, Sulman, S J, Jensen, C, Guo, J M, Maris, M D, Hogarty, C, Allen, J A, Biegel, T C, Matise, S G, Gregory, C P, Reynolds, G M, Brodeur
Publikováno v:
Medical and pediatric oncology. 36(1)
Several lines of evidence es tablish that chromosome band 1p36 is frequently deleted in neuroblastoma primary tumors and cell lines, suggesting that a tumor suppressor gene within this region is involved in the development of this tumor.We analyzed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82dc55cb6214bce2d7ec7b630b6c071c
https://pubmed.ncbi.nlm.nih.gov/11464901
https://pubmed.ncbi.nlm.nih.gov/11464901
Publikováno v:
Medical and pediatric oncology. 36(1)
Favorable neuroblastomas frequently express high levels of the TrkA receptor, and these tumors have a propensity to either differentiate or regress, but the mechanisms responsible for these two fates are unclear.To study TrkA signal transduction in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0559861e477b97650a03131cfedda7f
https://pubmed.ncbi.nlm.nih.gov/11464858
https://pubmed.ncbi.nlm.nih.gov/11464858
Autor:
M D, Hogarty, X, Liu, C, Guo, P M, Thompson, M J, Weiss, P S, White, E P, Sulman, G M, Brodeur, J M, Maris
Publikováno v:
Medical and pediatric oncology. 35(6)
Deletion of the distal short arm of chromosome 1 occurs frequently in neuroblastoma. In addition, neuroblastoma has been described in children with constitutional deletions within 1p36, supporting the existence of one or more neuroblastoma suppressor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e3946b2fd3022170028bd6015f55e3d
https://pubmed.ncbi.nlm.nih.gov/11107105
https://pubmed.ncbi.nlm.nih.gov/11107105
Publikováno v:
Medical and pediatric oncology. 35(6)
Mechanisms regulating the expression of angiogenic factors in tumor cells are largely unknown. High expression of the neurotrophin receptor TrkA in neuroblastomas (NB) is associated with favorable prognosis, whereas TrkB is expressed on aggressive, M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a757d665723fcde354efeb95dfddf8b1
https://pubmed.ncbi.nlm.nih.gov/11107119
https://pubmed.ncbi.nlm.nih.gov/11107119