Zobrazeno 1 - 10
of 300
pro vyhledávání: '"G Loots"'
Autor:
W F Venter, B Kaiser, Y Pillay, F Conradie, G B Gomez, P Clayden, M Matsolo, C Amole, L Rutter, F Abdullah, E J Abrams, C P Casas, M Barnhart, A Pillay, A Pozniak, A Hill, L Fairlie, M Boffito, M Moorhouse, M Chersich, C Serenata, J Quevedo, G Loots
Publikováno v:
South African Medical Journal, Vol 107, Iss 1, Pp 28-30 (2017)
Antiretrovirals are a significant cost driver for HIV programmes. Current first-line regimens have performed well in real-life programmes, but have a low barrier to virological resistance and still carry toxicity that limits adherence. New drug devel
Externí odkaz:
https://doaj.org/article/76ad91b37a024aeb8da0144b9355057c
Autor:
Susana Tejeda-Garibay, Lihong Zhao, Nicholas R. Hum, Maria Pimentel, Anh L. Diep, Beheshta Amiri, Suzanne S. Sindi, Dina R. Weilhammer, Gabriela G. Loots, Katrina K. Hoyer
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Coccidioidomycosis, also known as Valley fever, is a disease caused by the fungal pathogen Coccidioides. Unfortunately, patients are often misdiagnosed with bacterial pneumonia, leading to inappropriate antibiotic treatment. The soil Bacillu
Externí odkaz:
https://doaj.org/article/cd7d8d3c7c3c492f8b562e20e318645b
Autor:
Keith D. Morrison, Meghan B. Reiss, Tanya D. Tanner, Travis R. Gollott, Gabriela G. Loots, Nicole M. Collette
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The development of new antibiotics has stalled, and novel strategies are needed as we enter the age of antibiotic resistance. Certain naturally occurring clays have been shown to be effective in killing antibiotic resistant bacteria. However
Externí odkaz:
https://doaj.org/article/3a3cf73b260d4e8dbc2ece575e232379
Autor:
Aimy Sebastian, Kelly A. Martin, Ivana Peran, Nicholas R. Hum, Nicole F. Leon, Beheshta Amiri, Stephen P. Wilson, Matthew A. Coleman, Elizabeth K. Wheeler, Stephen W. Byers, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the top five deadliest forms of cancer with very few treatment options. The 5-year survival rate for PDAC is 10% following diagnosis. Cadherin 11 (Cdh11), a cell-to-cell adhesion molecule, has been su
Externí odkaz:
https://doaj.org/article/50a6f40489714f8794e255c10b83ab8d
Publikováno v:
JBMR Plus, Vol 7, Iss 8, Pp n/a-n/a (2023)
ABSTRACT Post traumatic osteoarthritis (PTOA) is a form of secondary osteoarthritis (OA) that develops in ~50% of cases of severe articular joint injuries and leads to chronic and progressive degradation of articular cartilage and other joint tissues
Externí odkaz:
https://doaj.org/article/b37e7ffbb8014fad819f0e3a0cb6d3b8
Autor:
Sarah V. Mendoza, Deepa K. Murugesh, Blaine A. Christiansen, Zoe O. Genetos, Gabriela G. Loots, Damian C. Genetos, Clare E. Yellowley
Publikováno v:
JBMR Plus, Vol 7, Iss 4, Pp n/a-n/a (2023)
ABSTRACT Molecular oxygen levels vary during development and disease. Adaptations to decreased oxygen bioavailability (hypoxia) are mediated by hypoxia‐inducible factor (HIF) transcription factors. HIFs are composed of an oxygen‐dependent α subu
Externí odkaz:
https://doaj.org/article/745d2379944a48efb944772743c74359
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 1002 (2023)
Valley fever or coccidioidomycosis is a pulmonary infection caused by species of Coccidioides fungi that are endemic to California and Arizona. Skeletal coccidioidomycosis accounts for about half of disseminated infections, with the vertebral spine b
Externí odkaz:
https://doaj.org/article/944c13df2bcd489ebfdb9f5c9928213e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The overuse of antibiotics in clinical and livestock settings is accelerating the selection of multidrug resistant bacterial pathogens. Antibiotic resistant bacteria result in increased mortality and financial strain on the health care and l
Externí odkaz:
https://doaj.org/article/4eb68295c0204935a66ae6e7dccde002
Autor:
Aimy Sebastian, Nicholas R. Hum, Jillian L. McCool, Stephen P. Wilson, Deepa K. Murugesh, Kelly A. Martin, Naiomy Deliz Rios-Arce, Beheshta Amiri, Blaine A. Christiansen, Gabriela G. Loots
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people world-wide. Accumulating evidence attests to the important roles of the immune system in OA pathogenesis. Understanding the role of various immune cells in joint
Externí odkaz:
https://doaj.org/article/f300656bbb3c4474aac3fe6b2c690ffd
Autor:
Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Due to lack of targetable receptors and intertumoral heterogeneity, triple negative breast cancer (TNBC) remains particularly difficult to treat. Doxorubicin (DOX) is typically used as nonselective neoadjuvant chemotherapy, but the diversity of treat
Externí odkaz:
https://doaj.org/article/c68fb0a68f6b4394a52c6b409b8dbd81