Zobrazeno 1 - 10
of 238
pro vyhledávání: '"G Larry Maxwell"'
Autor:
Hong Im Kim, Chad R Schultz, Andrea L Buras, Elizabeth Friedman, Alyssa Fedorko, Leigh Seamon, Gadisetti V R Chandramouli, G Larry Maxwell, André S Bachmann, John I Risinger
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189044 (2017)
Ornithine Decarboxylase (ODC) a key enzyme in polyamine biosynthesis is often overexpressed in cancers and contributes to polyamine-induced cell proliferation. We noted ubiquitous expression of ODC1 in our published endometrial cancer gene array data
Externí odkaz:
https://doaj.org/article/493769d495114577beac397315f42d7f
Autor:
Nicholas W. Bateman, Tamara Abulez, Anthony R. Soltis, Andrew McPherson, Seongmin Choi, Dale W. Garsed, Ahwan Pandey, Chunqiao Tian, Brian L. Hood, Kelly A. Conrads, Pang-ning Teng, Julie Oliver, Glenn Gist, Dave Mitchell, Tracy J. Litzi, Christopher M. Tarney, Barbara A. Crothers, Paulette Mhawech-Fauceglia, Clifton L. Dalgard, Matthew D. Wilkerson, Mariaelena Pierobon, Emanuel F. Petricoin, Chunhua Yan, Daoud Meerzaman, Clara Bodelon, Nicolas Wentzensen, Jerry S. H. Lee, The APOLLO Research Network, David G. Huntsman, Sohrab Shah, Craig D. Shriver, Neil T. Phippen, Kathleen M. Darcy, David D. L. Bowtell, Thomas P. Conrads, G. Larry Maxwell
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-17 (2024)
Abstract We performed a deep proteogenomic analysis of bulk tumor and laser microdissection enriched tumor cell populations from high-grade serous ovarian cancer (HGSOC) tissue specimens spanning a broad spectrum of purity. We identified patients wit
Externí odkaz:
https://doaj.org/article/24fb205468404dc8816ab7d41beb50e4
Autor:
Thomas Buddenkotte, Leonardo Rundo, Ramona Woitek, Lorena Escudero Sanchez, Lucian Beer, Mireia Crispin-Ortuzar, Christian Etmann, Subhadip Mukherjee, Vlad Bura, Cathal McCague, Hilal Sahin, Roxana Pintican, Marta Zerunian, Iris Allajbeu, Naveena Singh, Anju Sahdev, Laura Havrilesky, David E. Cohn, Nicholas W. Bateman, Thomas P. Conrads, Kathleen M. Darcy, G. Larry Maxwell, John B. Freymann, Ozan Öktem, James D. Brenton, Evis Sala, Carola-Bibiane Schönlieb
Publikováno v:
European Radiology Experimental, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Purpose To determine if pelvic/ovarian and omental lesions of ovarian cancer can be reliably segmented on computed tomography (CT) using fully automated deep learning-based methods. Methods A deep learning model for the two most common disea
Externí odkaz:
https://doaj.org/article/d86351df71064c6098a739ef36b913d9
Autor:
Sara Corvigno, Sunil Badal, Meredith L. Spradlin, Michael Keating, Igor Pereira, Elaine Stur, Emine Bayraktar, Katherine I. Foster, Nicholas W. Bateman, Waleed Barakat, Kathleen M. Darcy, Thomas P. Conrads, G. Larry Maxwell, Philip L. Lorenzi, Susan K. Lutgendorf, Yunfei Wen, Li Zhao, Premal H. Thaker, Michael J. Goodheart, Jinsong Liu, Nicole Fleming, Sanghoon Lee, Livia S. Eberlin, Anil K. Sood
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-26 (2023)
Abstract In this study, we investigated the metabolic alterations associated with clinical response to chemotherapy in patients with ovarian cancer. Pre- and post-neoadjuvant chemotherapy (NACT) tissues from patients with high-grade serous ovarian ca
Externí odkaz:
https://doaj.org/article/6cd6335bee5943da92c6a3557efb08a7
Autor:
John P. McGee, Pei Su, Kenneth R. Durbin, Michael A. R. Hollas, Nicholas W. Bateman, G. Larry Maxwell, Thomas P. Conrads, Ryan T. Fellers, Rafael D. Melani, Jeannie M. Camarillo, Jared O. Kafader, Neil L. Kelleher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The molecular identification of tissue proteoforms by top-down mass spectrometry (TDMS) is significantly limited by throughput and dynamic range. We introduce AutoPiMS, a single-ion MS based multiplexed workflow for top-down tandem MS (MS2)
Externí odkaz:
https://doaj.org/article/7587327dde1148caba435a60d10f292c
Autor:
Pang-ning Teng, Waleed Barakat, Sophie M. Tran, Zoe M. Tran, Nicholas W. Bateman, Kelly A. Conrads, Katlin N. Wilson, Julie Oliver, Glenn Gist, Brian L. Hood, Ming Zhou, G. Larry Maxwell, Lorenzo Leggio, Thomas P. Conrads, Mary R. Lee
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Alcohol use disorder (AUD) affects transcriptomic, epigenetic and proteomic expression in several organs, including the brain. There has not been a comprehensive analysis of altered protein abundance focusing on the multiple brain regions th
Externí odkaz:
https://doaj.org/article/0e74ad76aab64490aab99de2055aebe9
Autor:
Pang-ning Teng, Joshua P. Schaaf, Tamara Abulez, Brian L. Hood, Katlin N. Wilson, Tracy J. Litzi, David Mitchell, Kelly A. Conrads, Allison L. Hunt, Victoria Olowu, Julie Oliver, Fred S. Park, Marshé Edwards, AiChun Chiang, Matthew D. Wilkerson, Praveen-Kumar Raj-Kumar, Christopher M. Tarney, Kathleen M. Darcy, Neil T. Phippen, G. Larry Maxwell, Thomas P. Conrads, Nicholas W. Bateman
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109198- (2024)
Summary: Numerous multi-omic investigations of cancer tissue have documented varying and poor pairwise transcript:protein quantitative correlations, and most deconvolution tools aiming to predict cell type proportions (cell admixture) have been devel
Externí odkaz:
https://doaj.org/article/87a62e3f792e48a18b676967436cc62a
Autor:
Kalpana Deepa Priya Dorayappan, Vincent Wagner, Dongju Park, Meghan M. Newcomer, Michelle D. S. Lightfoot, Deepika Kalaiyarasan, Takahiko Sakaue, Wafa Khadraoui, Lianbo Yu, Qi‐En Wang, G. Larry Maxwell, David O'Malley, Raphael E. Pollock, David E. Cohn, Karuppaiyah Selvendiran
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract The interferon stimulated gene 15 (ISG15), a ubiquitin like protein and its conjugates have been implicated in various human malignancies. However, its role in ovarian cancer progression and metastasis is largely unknown. In high grade serou
Externí odkaz:
https://doaj.org/article/f6bfaf655b154822a7ca93373c6a0dd6
Autor:
Nicholas W. Bateman, Tamara Abulez, Anthony R. Soltis, Andrew McPherson, Seongmin Choi, Dale W. Garsed, Ahwan Pandey, Chunqiao Tian, Brian L. Hood, Kelly A. Conrads, Pang-ning Teng, Julie Oliver, Glenn Gist, Dave Mitchell, Tracy J. Litzi, Christopher M. Tarney, Barbara A. Crothers, Paulette Mhawech-Fauceglia, Clifton L. Dalgard, Matthew D. Wilkerson, Mariaelena Pierobon, Emanuel F. Petricoin, Chunhua Yan, Daoud Meerzaman, Clara Bodelon, Nicolas Wentzensen, Jerry S. H. Lee, The APOLLO Research Network, David G. Huntsman, Sohrab Shah, Craig D. Shriver, Neil T. Phippen, Kathleen M. Darcy, David D. L. Bowtell, Thomas P. Conrads, G. Larry Maxwell
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/0fd6d7e0522640fb848fd7d8ca72ab88
Autor:
Uksha Saini, Brentley Q. Smith, Kalpana Deepa Priya Dorayappan, Ji Young Yoo, G. Larry Maxwell, Balveen Kaur, Ikuo Konishi, David O’Malley, David E. Cohn, Karuppaiyah Selvendiran
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/9e8be0d153694a1fa8fe12a2fe3e034b