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Akademický článek

Effect of food additives on key bacterial taxa and the mucosa-associated microbiota in Crohn’s disease. The ENIGMA study

Autor: J.J. Jimenez Loayza, S. Kang, L. Schooth, J. J. Teh, A. de Klerk, E. K. Noon, J. Zhang, J. Hu, A. L. Hamilton, A. Wilson-O’Brien, G. L. Trakman, W. Lin, J. Ching, L. Or, J.J.Y. Sung, J. Yu, S.C. Ng, M.A. Kamm, M. Morrison

Publikováno v: Gut Microbes, Vol 15, Iss 1 (2023)

ABSTRACTFood additives have been linked to the pro-inflammatory microbial dysbiosis associated with Crohn’s disease (CD) but the underlying ecological dynamics are unknown. Here, we examine how selection of food additives affects the growth of mult

Externí odkaz: https://doaj.org/article/4618be7cc6ef4409816993252aeb1561

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DOP48 Key Anti-Inflammatory Faecalibacterium prausnitzii is Heterogeneous and Diverse in the East and West and in Health and Crohn’s disease. The ENIGMA study

Autor: J J Teh, S Kang, A Leonard, J Zhang, J Hu, A L Hamilton, A Wilson-O'Brien, G L Trakman, W Lin, J Ching, J J Y Sung, J Yu, S C Ng, M A Kamm, M Morrison

Publikováno v: Journal of Crohn's and Colitis. 17:i116-i119

Background There is insufficient knowledge about the key characteristics of the pathogenic and protective bacteria in inflammatory bowel disease. The ENIGMA study aimed to identify the phylogenetic and functional characteristics of Faecalibacterium p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ea457e005514827237864cb209324f1
https://doi.org/10.1093/ecco-jcc/jjac190.0088

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P925 Deep functional assessment of the colonic mucosa-associated microbiota in Crohn's disease and health identifies pro- and anti- inflammatory secretomes and associated bacterial consortia. The ENIGMA study

Autor: J J Teh, S Kang, J Zhang, J Hu, A L Hamilton, A Wilson-O'Brien, G L Trakman, W Lin, J Ching, J J Y Sung, J Yu, S C Ng, M A Kamm, M Morrison

Publikováno v: Journal of Crohn's and Colitis. 17:i1035-i1035

Background Gut microbial dysbiosis and dysregulated host immune responses are key factors implicated in Crohn’s disease pathogenesis. However, the nexus between the mucosa-associated microbiota (MAM) and epithelial cell immune response(s) remains p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea92296d6117416f315fa64975c26306
https://doi.org/10.1093/ecco-jcc/jjac190.1055

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DOP49 Metagenomic Characterisation of The Colonic Mucosa-Associated Microbiota Reveals Novel Microbes and Communities in Health and Crohn’s disease. The ENIGMA study

Autor: S Kang, J J Teh, J Zhang, J Hu, A L Hamilton, A Wilson-O'Brien, G L Trakman, W Lin, J Ching, J J Y Sung, J Yu, S C Ng, M A Kamm, M Morrison

Publikováno v: Journal of Crohn's and Colitis. 17:i119-i119

Background Deep functional understanding of the mucosa-associated microbiota (MAM) in Crohn’s disease and health by DNA sequencing approaches is restricted by the dominance of human DNA in samples. We established an ex vivo combination of tissue pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::963ec2e25d6839edad2aaf825435ac5b
https://doi.org/10.1093/ecco-jcc/jjac190.0089

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