Zobrazeno 1 - 10
of 24
pro vyhledávání: '"G L Spitalny"'
Publikováno v:
The Journal of Immunology. 150:5241-5251
Granulocyte-macrophage (GM)-CSF is an important hematopoietic cytokine that regulates proliferation and differentiation of macrophages, neutrophils, and eosinophils. In this study, we generated mAb to five synthetic peptides that correspond to region
Autor:
I, Bursuker, K M, Neddermann, B A, Petty, B, Schacter, G L, Spitalny, M A, Tepper, R D, Pasternak
Publikováno v:
Experimental hematology. 20(4)
Injection of mice with either natural bovine bone-derived or human recombinant transforming growth factor beta 1 (TGF-beta 1) resulted in a significant increase of the macrophage and macrophage-granulocyte-forming capacity of their macrophage colony-
Autor:
M A, Tepper, B, Petty, I, Bursuker, R D, Pasternak, J, Cleaveland, G L, Spitalny, B, Schacter
Publikováno v:
Transplantation proceedings. 23(1 Pt 1)
Autor:
R S, Greenfield, T, Kaneko, A, Daues, M A, Edson, K A, Fitzgerald, L J, Olech, J A, Grattan, G L, Spitalny, G R, Braslawsky
Publikováno v:
Cancer research. 50(20)
A novel method for linking Adriamycin (ADM) to monoclonal antibodies is described in which the 13-keto position of the anthracycline is used as the attachment site to the linker arm. A new ADM acylhydrazone derivative, Adriamycin 13-[3-(2-pyridyldith
Autor:
E A Havell, G L Spitalny
Publikováno v:
The Journal of Experimental Medicine
Fusion of rat immune spleen cells with mouse myeloma cells resulted in the formation of a stable hybridoma that secretes monoclonal antibody (MAb) directed against murine gamma interferon ( MuIFN -gamma). This MAb specifically neutralized the antivir
Autor:
G L Spitalny, J R Fahey
Publikováno v:
Infection and Immunity. 55:490-493
Protective immunity against a lethal malaria challenge infection was passively transferred to naive recipient mice with spleen cells from donor mice bearing a lethal infection with the virulent YM strain of Plasmodium yoelii. Successful transfer of p
Publikováno v:
The Journal of Immunology. 137:3494-3500
The induction of cytotoxic T lymphocytes (CTL) from CTL precursors requires a combination of antigen and lymphokine signals. To investigate lymphokine requirements for CTL generation, we used an assay in which helper T cell and accessory cell-deplete
Publikováno v:
The Journal of Immunology. 136:2917-2923
A monoclonal antibody (MAb) with specificity for murine interferon-gamma (IFN-gamma) was used as a probe for studying the effect of recombinant IFN-gamma (rIFN-gamma) on antiviral activity, Fc receptor expression, and Ia antigen induction in macropha
Autor:
G L Spitalny, J R Fahey
Publikováno v:
Infection and Immunity. 44:151-156
The present studies were designed to investigate whether the erythrocyte preferences displayed by both virulent and nonvirulent forms of Plasmodium yoelii were fastidious growth requirements of these parasites. When inoculated into mice depleted of r
Publikováno v:
The Journal of Immunology. 134:1619-1622
To determine the role of IFN-gamma in the activation of resident mouse peritoneal macrophages, crude macrophage-activating lymphokines were incubated with a monoclonal anti-murine IFN-gamma antibody. This treatment abolished the capacity of mitogen-i