Výsledky vyhledávání - "G L Firestone"

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

Autor: M K Webster, L Goya, Y Ge, A C Maiyar, G L Firestone

Publikováno v: Molecular and Cellular Biology. 13:2031-2040

A novel member of the serine/threonine protein kinase gene family, designated sgk, for serum and glucocorticoid-regulated kinase, was identified in a differential screen for glucocorticoid-inducible transcripts expressed in the Con8.hd6 rat mammary t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e15541f751afb6372bfdf5e6e80a983c
https://doi.org/10.1128/mcb.13.4.2031

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Expression and localization of serum/glucocorticoid-induced kinase in the rat ovary: relation to follicular growth and differentiation

Autor: T N, Alliston, I J, Gonzalez-Robayna, P, Buse, G L, Firestone, J S, Richards

Publikováno v: Endocrinology. 141(1)

Expression of serum/glucocorticoid-inducible kinase (Sgk), one member of an inducible serine/threonine kinase family, is induced by FSH/cAMP in rat granulosa cells cultured in defined medium. The FSH-stimulated pattern of sgk expression is biphasic,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8f912f7b23f20a1efd74dfd8a9655dc
https://pubmed.ncbi.nlm.nih.gov/10614661

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Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum- and glucocorticoid-inducible protein kinase, Sgk, in mammary tumor cells. A novel convergence point of anti-proliferative and proliferative cell signaling pathways

Autor: P, Buse, S H, Tran, E, Luther, P T, Phu, G W, Aponte, G L, Firestone

Publikováno v: The Journal of biological chemistry. 274(11)

The serum- and glucocorticoid-inducible kinase (sgk) is a novel serine/threonine protein kinase that is transcriptionally regulated in rat mammary tumor cells by serum under proliferative conditions or by glucocorticoids that induce a G1 cell cycle a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f13f8f211a91731a274df86fed332b88
https://pubmed.ncbi.nlm.nih.gov/10066787

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Role of the CCAAT/enhancer binding protein-alpha transcription factor in the glucocorticoid stimulation of p21waf1/cip1 gene promoter activity in growth-arrested rat hepatoma cells

Autor: E J, Cram, R A, Ramos, E C, Wang, H H, Cha, Y, Nishio, G L, Firestone

Publikováno v: The Journal of biological chemistry. 273(4)

The preceding paper (Cha, H. H., Cram, E. J., Wang, E. C., Huang, A. J., Kasler, H. G., and Firestone, G. L. (1998) J. Biol. Chem. 273, 0000-0000(478563) defined a glucocorticoid responsive region within teh promoter of the p21 CDK inhibitor gene tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a434041740e4263edbe4818e931c952a
https://pubmed.ncbi.nlm.nih.gov/9442037

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Glucocorticoids stimulate p21 gene expression by targeting multiple transcriptional elements within a steroid responsive region of the p21waf1/cip1 promoter in rat hepatoma cells

Autor: H H, Cha, E J, Cram, E C, Wang, A J, Huang, H G, Kasler, G L, Firestone

Publikováno v: The Journal of biological chemistry. 273(4)

Glucocorticoids can induce a G1 arrest in the cell cycle progression of BDS1 rat hepatoma cells. In these cells, dexamethasone, a synthetic glucocorticoid, stimulated a rapid and selective increase in expression of the p21 cyclin-dependent kinase (CD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c96f43daf004c9f2898d94a6d22c39ff
https://pubmed.ncbi.nlm.nih.gov/9442036

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Transforming growth factor beta down-regulation of CKShs1 transcripts in growth-inhibited epithelial cells

Autor: K E, Simon, H H, Cha, G L, Firestone

Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(10)

CKShs1 is a mammalian homologue of the yeast suc1 and CKS1 genes, for which the null mutation leads to arrest in both the G1 and G2 phases of the cell cycle in Saccharomyces cerevisiae. Northern blot analysis revealed that transcript levels of CKShs1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e49046fdac96dc17881f115075cd1e51
https://pubmed.ncbi.nlm.nih.gov/8845303

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Relationship of serine/threonine phosphorylation/dephosphorylation signaling to glucocorticoid regulation of tight junction permeability and ZO-1 distribution in nontransformed mammary epithelial cells

Autor: K L, Singer, B R, Stevenson, P L, Woo, G L, Firestone

Publikováno v: The Journal of biological chemistry. 269(23)

The synthetic glucocorticoid dexamethasone regulates tight junction permeability resulting in an increased transepithelial electrical resistance (TER) of cultured 31EG4 mammary epithelial cells. Inhibition of cellular type 1 and type 2A protein phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c16968412b23c713e0f7704dd6aaba4f
https://pubmed.ncbi.nlm.nih.gov/8206910

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Glucocorticoid-regulated trafficking of mouse mammary tumor virus proteins in permeabilized hepatoma cells. Requirements of intracellular membrane transport for maturation of the cytoplasmic phosphorylated polyprotein

Autor: S R, Kain, T I, Jen, G L, Firestone

Publikováno v: The Journal of biological chemistry. 268(26)

Glucocorticoids coincidentally regulate the localization of mouse mammary tumor virus (MMTV) glycoproteins and maturation of viral phosphoproteins in viral infected rat hepatoma cells. To test for a functional interaction between MMTV transmembrane g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48180e4068b725be6cb590f8e9abc868
https://pubmed.ncbi.nlm.nih.gov/8396142

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Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase

Autor: M K, Webster, L, Goya, G L, Firestone

Publikováno v: The Journal of biological chemistry. 268(16)

Serine/threonine protein kinases are important regulators of diverse cellular processes including metabolism, proliferation, and differentiation. We have previously identified the cDNA for a 49-kDa serine/threonine kinase, designated sgk, which is tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a4f6655f18e38d7d0bb8c41020b43e2
https://pubmed.ncbi.nlm.nih.gov/8505283

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