Výsledky vyhledávání - "G L, Wampler"

Hormonal palliation of chemoresistant ovarian cancer: three consecutive phase II trials of the Mid-Atlantic Oncology Program

Autor: Jacob J. Lokich, K Y Yeung, G L Wampler, W Ueno, James D. Ahlgren, F Laluna, R J Gottlieb, P R Sinclair, N M Ellison, D Alt

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 11(10)

PURPOSE To evaluate the efficacy of three hormonal manipulations in the palliation of chemoresistant ovarian cancer, and to analyze the results in the light of other clinical trials. PATIENTS AND METHODS Three sequential phase II trials were performe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee43dd327c0673486aebf706df41c2f
https://pubmed.ncbi.nlm.nih.gov/7691999

Zobrazit plný text záznamu

A pilot study of intensive weekly chemotherapy for extensive disease small-cell lung carcinoma

Autor: G L, Wampler, J D, Ahlgren, R S, Schulof

Publikováno v: Cancer investigation. 10(2)

An intensive weekly chemotherapeutic treatment for extensive disease small-cell lung cancer was piloted in 14 patients. The regimen consisted of 6 drugs. Two drugs were given each week for a total of 12 weeks of treatment. Modifications were required

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d4c705415571a990c19df1e43142d0c9
https://pubmed.ncbi.nlm.nih.gov/1312886

Zobrazit plný text záznamu

Comparison of cyclophosphamide, doxorubicin, and vincristine with an alternating regimen of methotrexate, etoposide, and cisplatin/cyclophosphamide, doxorubicin, and vincristine in the treatment of extensive-disease small-cell lung carcinoma: a Mid-Atlantic Oncology Program study

Autor: James D. Ahlgren, William J. Heim, N M Ellison, John G. Fryer, G L Wampler

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 9(8)

An alternating regimen for the treatment of extensive-disease small-cell lung cancer (SCLC) was compared with standard treatment with cyclophosphamide, doxorubicin, and vincristine (CAV) in 170 patients. Overall severity of toxicity was similar in bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fff720dd8811097728ce71c8f04bac8
https://pubmed.ncbi.nlm.nih.gov/1649265

Zobrazit plný text záznamu

A prospective randomized comparison of protracted infusional 5-fluorouracil with or without weekly bolus cisplatin in metastatic colorectal carcinoma. A Mid-Atlantic Oncology Program study

Autor: J J, Lokich, J D, Ahlgren, J, Cantrell, W J, Heim, G L, Wampler, J J, Gullo, J G, Fryer, D E, Alt

Publikováno v: Cancer. 67(1)

One hundred eighty-four patients with advanced measurable colorectal cancer not previously treated with chemotherapy were entered into a prospective randomized clinical trial by the Mid-Atlantic Oncology Program (MAOP) to assess the value of weekly c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::86b5f701cb148aade6de519dbad9180b
https://pubmed.ncbi.nlm.nih.gov/1985710

Zobrazit plný text záznamu

Synthesis of bis(aziridinyl)phosphinyl-N-hydroxyurethane derivatives as antineoplastic agents

Autor: Y. Y. Hsiao, Thomas J. Bardos, G. L. Wampler, W. Regelson

Publikováno v: Journal of Medicinal Chemistry. 18:195-198

Several new "dual antagonists" were synthesized in which the 2,2-dimethyl (or ring C unsubstituted) aziridine phosphinyl function is linked to N-hydroxyurethane rather than the urethane moiety. Three of the new compounds showed very high activities a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d6e8aed376084e5bb9df00afc5917b
https://doi.org/10.1021/jm00236a019

Zobrazit plný text záznamu

On determining the levels of treatment to optimize the probability of a favorable response

Autor: W H, Carter, G L, Wampler, S L, Crews, R, Howells

Publikováno v: Cancer treatment reports. 61(5)

This paper presents a statistical method for analyzing the dose response surface associated with treatments resulting from combinations of any number of cytotoxic agents. The results of such an analysis are the dosages of each agent in the combinatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9b2c71b145ccfa6b935a4e89da2a1fe
https://pubmed.ncbi.nlm.nih.gov/408002

Zobrazit plný text záznamu

Antileukemic effect of homo-aza-steroidal ester of [p-[bis(2-chloroethyl)amino]phenyl]acetic acid

Autor: G L, Wampler, P, Catsoulacos

Publikováno v: Cancer treatment reports. 61(1)

The homo-aza-steroidal ester of [p-[bis(2-chloroethyl)amino]phenyl]acetic acid, 3beta-hydroxy-13alpha-amino-13,17-seco-5alpha-androstan-17-oic-13,17,-lactam p-bis(2-chloroethyl)aminophenylacetate (ASE), gives a greater than 50% increased lifespan ove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84347e304689dc8a5612091167a1c20d
https://pubmed.ncbi.nlm.nih.gov/861962

Zobrazit plný text záznamu

New ribonucleotide reductase inhibitors with antineoplastic activity

Autor: H L, Elford, G L, Wampler, B, van't Riet

Publikováno v: Cancer research. 39(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df210dc0e52940681021fedb20285ab2
https://pubmed.ncbi.nlm.nih.gov/427774

Zobrazit plný text záznamu

Confidence regions for constrained optima in response-surface experiments

Autor: D M, Stablein, W H, Carter, G L, Wampler

Publikováno v: Biometrics. 39(3)

The precision of the estimated optimum from a response-surface experiment is often indicated via a confidence region about the optimum. Sometimes, because of associated secondary responses, unconstrained optima produce unrealistic operating condition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbcedc4e7f0943b85ec40136c278cc73
https://pubmed.ncbi.nlm.nih.gov/6652206

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání