Zobrazeno 1 - 10
of 14
pro vyhledávání: '"G L, Rosner"'
Autor:
Gini F. Fleming, John L. Marshall, C. Enders Klein, M. Villalona, Raymond J. Hohl, Donna Hollis, John C. Byrd, Helen Kastrissios, Joel Ramirez, Daniel R. Budman, C. G. Leichman, Mark J. Ratain, G. L. Rosner, Alan P. Venook
Publikováno v:
Annals of Oncology. 14:1783-1790
BACKGROUND To ascertain if hepatic or renal dysfunction or prior pelvic radiation (XRT) leads to increased toxicity at a given dose of irinotecan and to characterize the pharmacokinetics of irinotecan and its major metabolites in patients with hepati
Publikováno v:
American Journal of Public Health. 84:14-19
OBJECTIVES. The purpose of this study was to test the hypothesis that overall and truncal adiposity increase the risk of stroke independent of their association with cardiovascular disease risk factors and other preexisting illnesses. METHODS. Analys
Autor:
B L, Samuels, D R, Hollis, G L, Rosner, D L, Trump, C L, Shapiro, N J, Vogelzang, R L, Schilsky
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(11)
Multidrug resistance mediated by P-glycoprotein may be an important cause of chemotherapy failure. Renal cell carcinoma is a disease known to demonstrate a high degree of intrinsic chemotherapy drug resistance, and this has been shown to be related t
Autor:
J C, Acker, L B, Marks, D P, Spencer, W, Yang, M A, Avery, R K, Dodge, G L, Rosner, M W, Dewhirst
Publikováno v:
Radiation research. 149(4)
To test whether single high doses of radiation, similar to those used with radiosurgery, given to normal cerebral vasculature can cause changes in leukocyte-vessel wall interactions and tissue perfusion, a rat pial window model was used to view the c
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(5)
This was a pharmacological companion study to a randomized Phase III trial comparing 21-day oral versus 3-day i.v. etoposide in combination with i.v. cisplatin in patients with extensive-stage small cell lung cancer. Etoposide plasma concentrations w
Autor:
G L, Rosner, P, Müller
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 25(2)
Population studies of the pharmacokinetics or pharmacodynamics of drugs help us, learn about the variability in drug disposition and effects, information that can be used to treat future patients at safe and effective doses. We present a new approach
Autor:
J S, Hahn, R D, Braun, M W, Dewhirst, S, Shan, S A, Snyder, J M, Taube, E T, Ong, G L, Rosner, R K, Dodge, J, Bonaventura, C, Bonaventura, J, DeAngelo, R E, Meyer
Publikováno v:
Radiation research. 147(2)
We examined the effect of a nitric oxide (NO) quencher, stroma-free human hemoglobin A (HbA0; 0.01, 0.05, 0.1, 0.2 g/kg), on the blood flow measured using the Doppler flow technique, tumor oxygen pressure (pO2) and the diameter of the arterioles usin
Autor:
I. C. Henderson, Jeffrey B. Hargis, Richard L. Schilsky, G. L. Rosner, Daniel R. Budman, Donna Hollis, Raymond B. Weiss
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 14(11)
PURPOSE We examined data from a large clinical trial to determine if chemotherapy dosing according to actual body weight places obese patients at greater risk of toxicity. PATIENTS AND METHODS Cancer and Leukemia Group B (CALGB) study 8541, a randomi
Autor:
W P, Petros, G L, Rosner, J, Rabinowitz, C J, Gilbert, D, Coniglio, J J, Vredenburgh, M, Ross, W P, Peters
Publikováno v:
Pharmacotherapy. 16(5)
To investigate the effect of colony-stimulating factors (CSFs) on drug metabolism using theophylline as a substrate (phase I), and to evaluate the influence of theophylline on endogenous serum cytokine concentrations (phase II).Open-label, prospectiv
Publikováno v:
Cancer. 74(11)
Forty patients with Stage II-III breast cancer with 10 or more positive axillary nodes were treated with mastectomy followed by four cycles of standard dose CAF (cytoxan, Adriamycin, 5-FU), followed by high dose cytoxan, cisplatin, carmustine (HDCT)