Výsledky vyhledávání

Changes in endometrial PTEN expression throughout the human menstrual cycle

Autor: G L, Mutter, M C, Lin, J T, Fitzgerald, J B, Kum, C, Eng

Publikováno v: The Journal of clinical endocrinology and metabolism. 85(6)

Frequent mutation of the PTEN tumor suppressor gene in endometrial adenocarcinoma has led to the prediction that its product, a phosphatase that regulates the cell cycle, apoptosis, and possibly cell adhesion, is functionally active within normal end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8244ebb2e7948664a706999b0dfbd1f8
https://pubmed.ncbi.nlm.nih.gov/10852473

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Linking gene expression patterns to therapeutic groups in breast cancer

Autor: K J, Martin, B M, Kritzman, L M, Price, B, Koh, C P, Kwan, X, Zhang, A, Mackay, M J, O'Hare, C M, Kaelin, G L, Mutter, A B, Pardee, R, Sager

Publikováno v: Cancer research. 60(8)

A major objective of current cancer research is to develop a detailed molecular characterization of tumor cells and tissues that is linked to clinical information. Toward this end, we have identified approximately one-quarter of all genes that were a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8afd791b26b06f206a6653ab2d584bc6
https://pubmed.ncbi.nlm.nih.gov/10786689

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Endometrial precancer diagnosis by histopathology, clonal analysis, and computerized morphometry

Autor: G L, Mutter, J P, Baak, C P, Crum, R M, Richart, A, Ferenczy, W C, Faquin

Publikováno v: The Journal of pathology. 190(4)

Management of endometrial precancers is compromised by longstanding debate over the natural history of endometrial hyperplasias and inconsistencies in their diagnosis. The recent demonstration that some hyperplasias, like cancers, are phenotypically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9106aca9a060a210bcd5419d400e500c
https://pubmed.ncbi.nlm.nih.gov/10699996

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Endometrial intraepithelial neoplasia (EIN): will it bring order to chaos? The Endometrial Collaborative Group

Autor: G L, Mutter

Publikováno v: Gynecologic oncology. 76(3)

The diagnosis of precancerous lesions of the endometrium remains unstandardized because existing World Health Organization classification categories do not correspond to distinctive biologic groups and are inadequately supported by reproducible histo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43b5068690947204124b80125089b950
https://pubmed.ncbi.nlm.nih.gov/10684697

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Mucinous endometrial epithelial proliferations: a morphologic spectrum of changes with diverse clinical significance

Autor: M R, Nucci, C J, Prasad, C P, Crum, G L, Mutter

Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 12(12)

Mucinous differentiation of the endometrium can occur in a spectrum of changes ranging from benign (metaplasia) to malignant (adenocarcinomas with mucinous differentiation). Mucinous proliferations with simple architecture are generally considered be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e17826c48faf679895abb39d04b893e0
https://pubmed.ncbi.nlm.nih.gov/10619266

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Disseminated peritoneal leiomyomatosis. Clonality analysis by X chromosome inactivation and cytogenetics of a clinically benign smooth muscle proliferation

Autor: B J, Quade, C M, McLachlin, V, Soto-Wright, J, Zuckerman, G L, Mutter, C C, Morton

Publikováno v: The American journal of pathology. 150(6)

Disseminated peritoneal leiomyomatosis (DPL, leiomyomatosis peritonealis disseminata) is a rare condition in which multiple histologically benign smooth muscle tumorlets diffusely stud peritoneal and omental surfaces in females, predominantly of repr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1be1ebf7c00c34000d2a187fa4918ae
https://pubmed.ncbi.nlm.nih.gov/9176406

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Pathobiology of vulvar squamous neoplasia

Autor: C P, Crum, C M, McLachlin, J E, Tate, G L, Mutter

Publikováno v: Current opinion in obstetricsgynecology. 9(1)

Vulvar squamous carcinoma is an uncommon neoplasm that afflicts a spectrum of women and has been associated with granulomatous vulvar diseases, papillomaviruses, and chronic inflammatory disorders of the vulva. Histopathological, molecular, and epide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a9a72b1a90de4acfc682c4721cb68df
https://pubmed.ncbi.nlm.nih.gov/9090485

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Expression of DAZ, an azoospermia factor candidate, in human spermatogonia

Autor: D B, Menke, G L, Mutter, D C, Page

Publikováno v: American journal of human genetics. 60(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::169bbc3f871c58581a42055bf704e2cf
https://pubmed.ncbi.nlm.nih.gov/8981970

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Uteri of women with endometrial carcinoma contain a histopathological spectrum of monoclonal putative precancers, some with microsatellite instability

Autor: A S, Jovanovic, K A, Boynton, G L, Mutter

Publikováno v: Cancer research. 56(8)

We have tested the hypothesis that endometrial precancers persist in uteri of patients with endometrial carcinoma and are monoclonal. Twenty-two hysterectomies with both well-differentiated endometrial adenocarcinoma and adjacent (normal or abnormal)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73f85d4acbdf89ab2942950c8df6ce6b
https://pubmed.ncbi.nlm.nih.gov/8620514

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