Zobrazeno 1 - 10
of 15
pro vyhledávání: '"G L, Forrest"'
Publikováno v:
Archives of Biochemistry and Biophysics. 321:76-82
NAD(P)H: quinone-acceptor oxidoreductase (EC 1.6.99.2), also referred to as DT-diaphorase, is a flavo-protein that catalyzes the two-electron reduction of quinones and quinonoid compounds to hydroquinones, using either NADH or NADPH as the electron d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a888070d7bfce6ca4970f33ef1f23e
https://doi.org/10.1006/abbi.1995.1370
https://doi.org/10.1006/abbi.1995.1370
Publikováno v:
Cancer research. 60(18)
Doxorubicinol (dxol) is the major metabolite formed in the hearts of cancer patients being treated with the widely used chemotherapeutic agent, doxorubicin (dox). The well-documented cardiomyopathy associated with dox treatment has been studied in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::297fdc77ecc35e7c0c0d696a430087f4
https://pubmed.ncbi.nlm.nih.gov/11016643
https://pubmed.ncbi.nlm.nih.gov/11016643
Publikováno v:
Cancer research. 55(20)
Carbonyl reductase (CBR) catalyzes the reduction of daunorubicin (DN) to its corresponding alcohol, daunorubicinol (DNOL), and changes the pharmacological properties of this cancer chemotherapeutic drug. The DN reductase associated with CBR reduces t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a04a6cef33764cfbeb97557234c7a9df
https://pubmed.ncbi.nlm.nih.gov/7553643
https://pubmed.ncbi.nlm.nih.gov/7553643
Publikováno v:
Cancer research. 55(2)
An association between the resistance to mitomycin C (MMC) and a decrease of NAD(P)H:quinone oxidoreductase (NQO1) activity was reported for a MMC-resistant subline, HCT 116-R30A, derived from MMC-sensitive HCT 116 cells. Eight NQO1 cDNA clones were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79b26af7563e8e6bf67c44b539d6b9cb
https://pubmed.ncbi.nlm.nih.gov/7812966
https://pubmed.ncbi.nlm.nih.gov/7812966
Autor:
A M, Malkinson, D, Siegel, G L, Forrest, A F, Gazdar, H K, Oie, D C, Chan, P A, Bunn, M, Mabry, D J, Dykes, S D, Harrison
Publikováno v:
Cancer research. 52(17)
The enzyme DT-diaphorase (DTD; NAD(P)H:quinone oxidoreductase, EC 1.6.99.2), is an obligate two electron reductase which catalyzes reduction of a broad range of substrates, including quinones. We report here variations in DTD concentrations among dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1da5ba7eff17df493bc67b42a0323fe8
https://pubmed.ncbi.nlm.nih.gov/1324793
https://pubmed.ncbi.nlm.nih.gov/1324793
Publikováno v:
The Biochemical journal. 284
A prokaryotic expression plasmid, pKK-DT2, containing the cDNA of rat liver NAD(P)H:quinone-acceptor oxidoreductase (EC 1.6.99.2; DT-diaphorase) was constructed and used to transform Escherichia coli strain JM109. The rat liver quinone reductase was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141499485acd4f468992ba428ab902fc
https://pubmed.ncbi.nlm.nih.gov/1622401
https://pubmed.ncbi.nlm.nih.gov/1622401
Autor:
Martin J. Tymms, Ismail Kola, J.A. Marshall Graves, S. Brookes, G. L. Forrest, J. B. de Haan, P. Maccarone
Publikováno v:
Cytogenetics and cell genetics. 61(1)
We have mapped the chromosomal location of four genes previously assigned to human chromosome 21—Cu/Zn superoxide dismutase (SOD1), the protooncogene ETS2, the interferon α/β receptor gene (IFNAR), and the carbonyl reduc-tase gene (CBR)—in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d0a2cce0814d415c17a6af1b1558af
https://pubmed.ncbi.nlm.nih.gov/1380419
https://pubmed.ncbi.nlm.nih.gov/1380419
Publikováno v:
Molecular pharmacology. 40(4)
Carbonyl reductase (NADPH: secondary-alcohol oxidoreductase; EC 1.1.1.184), a widely distributed NADPH-dependent enzyme considered as both an aldo-keto reductase and a quinone reductase, was cloned from a human liver genomic library and transiently e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc65070d7120454622c073787163ba3e
https://pubmed.ncbi.nlm.nih.gov/1921984
https://pubmed.ncbi.nlm.nih.gov/1921984
Autor:
R R Klevecz, G L Forrest
Publikováno v:
The Journal of Cell Biology
Tyrosyltubulin ligase (TTL) was found to be present in CHO and V79 Chinese hamster cells grown in tissue culture. The enzyme is soluble and requires potassium, magnesium, and ATP for maximum activity and requires tubulin as a substrate. TTL was analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2214cac27ab429b8a715b7414788e1e4
https://pubmed.ncbi.nlm.nih.gov/567652
https://pubmed.ncbi.nlm.nih.gov/567652
Autor:
J A, Ayulo, G L, Forrest
Publikováno v:
The American journal of gastroenterology. 64(3)
Determination of B-glucuronidase activity was carried out in 203 subjects including 60 controls. A modified technic for assaying B-glucuronidase activity was used that employs glass column chromatography and Sephadex. Although the lowest mean value w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fdb210778d825078d6ac86ed10c3bd4
https://pubmed.ncbi.nlm.nih.gov/1181924
https://pubmed.ncbi.nlm.nih.gov/1181924