Výsledky vyhledávání - "G L, Ferrell"

Identification of the protein C/activated protein C binding sites on the endothelial cell protein C receptor. Implications for a novel mode of ligand recognition by a major histocompatibility complex class 1-type receptor

Autor: P C, Liaw, T, Mather, N, Oganesyan, G L, Ferrell, C T, Esmon

Publikováno v: The Journal of biological chemistry. 276(11)

The endothelial cell protein C receptor (EPCR) is an endothelial cell-specific transmembrane protein that binds both protein C and activated protein C (APC). EPCR regulates the protein C anticoagulant pathway by binding protein C and augmenting prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a45963ef7586d255c0b8e45088e0d3ef
https://pubmed.ncbi.nlm.nih.gov/11099506

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Endotoxin and thrombin elevate rodent endothelial cell protein C receptor mRNA levels and increase receptor shedding in vivo

Autor: J M, Gu, Y, Katsuura, G L, Ferrell, P, Grammas, C T, Esmon

Publikováno v: Blood. 95(5)

The endothelial cell protein C receptor (EPCR) facilitates protein C activation by the thrombin-thrombomodulin complex. Protein C activation has been shown to be critical to the host defense against septic shock. In cell culture, tumor necrosis facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a45e8e434636158ab7ed079f5b46cff1
https://pubmed.ncbi.nlm.nih.gov/10688825

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