Zobrazeno 1 - 10
of 19
pro vyhledávání: '"G L, Coppoc"'
Publikováno v:
Equine Veterinary Journal. 21:24-28
Endotoxin (LPS) was quantitated in experimental subjects and in horses with naturally occurring gastrointestinal strangulation obstruction and/or septicaemic diseases to establish the fate of LPS and the clinical usefulness of the Limulus amoebocyte
Publikováno v:
American journal of veterinary research. 39(6)
Aprotinin, a proteinase inhibitor, was evaluated as a pharmacologic aid in dogs subjected to lethal hemorrhagic shock. Survival time, hemodynamic changes, and plasma enzyme analysis were measured as criteria for drug effects. Mixed-breed dogs (n = 14
Autor:
G L, Coppoc
Publikováno v:
Journal of the American Veterinary Medical Association. 185(10)
Publikováno v:
Research communications in chemical pathology and pharmacology. 33(3)
A single dose (15mg/kg) of the aminoglycoside antibiotic gentamicin was administered intravenously to 4 purebred 5-month old beagles. Six 24-hour creatinine, urea, phosphate, sodium, and potassium clearances were performed, three before and three aft
Publikováno v:
Journal of animal science. 55(1)
Studies were conducted to determine the absorption and metabolic fate of 3H-estradiol-17 beta-glucuronide (3H-E2-G) in swine. The conjugate, 3H-E2-G (48.7 x 10(6) DPM, 45.5 Ci/mmol), was injected into ligated 15-cm sections of duodenum, proximal jeju
Publikováno v:
American journal of veterinary research. 47(4)
Dose-related changes in the pharmacokinetics of gentamicin sulfate were investigated in 9 sheep given 3, 10, or 20 mg/kg of body weight IV in a crossover design with a 24-day washout period. The pharmacokinetics of the 3 mg/kg single dose were compar
Publikováno v:
Cancer research. 48(1)
The pharmacokinetics of i.p. administered dipyridamole was studied in six patients to explore the feasibility of using this drug as a modulator of antimetabolite activity in extravascular spaces. Infusions of dipyridamole (50 mg/m2 in 2 liters of nor
Autor:
J E, Riviere, G L, Coppoc
Publikováno v:
American journal of veterinary research. 42(9)
The pharmacokinetics of gentamicin and/or creatinine clearances were investigated in eleven 5-month-old Beagles. A 2-compartment open model was used to describe the drug's disposition, as judged by error sums of squares and residual plot analyses. Ha
Publikováno v:
Journal of the American Veterinary Medical Association. 180(6)
Three clinical cases of toxic nephropathy in young horses were ascribed to gentamicin toxicity. Criteria for defining gentamicin-induced nephrotoxicosis were a serum urea nitrogen value greater than the pretreatment value or cylindruria, hematuria, a
Publikováno v:
American journal of veterinary research. 41(4)
Investigation of pharmacokinetics of certain drugs in experimental models of glomerulonephritis would facilitate development of dose schedules for dogs with this disease. Polymerized polyvinyl alcohol (PVA)-induced glomerulonephritis was investigated