Zobrazeno 1 - 10
of 82
pro vyhledávání: '"G Krumbiegel"'
Publikováno v:
Hereditas. 103:65-71
Two major aspects of protoplast fusion are discussed. First, the combination of complete genomes by protoplast fusion of two different species either by using protoplasts of albino or auxotrophic mutants for a complementation selection, or by culturi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a87d48a0b3e3af3ea21b724de638a14b
https://doi.org/10.1111/j.1601-5223.1985.tb00751.x
https://doi.org/10.1111/j.1601-5223.1985.tb00751.x
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 42:543-549
Background and objectives: The antimuscarinic drug trospium chloride is hydrophilic and therefore does not enter the CNS when used for the treatment of overactive bladder disturbances. However, the same property is the main reason for low and variabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37591d636ec0d11ee98297790d33aff9
https://doi.org/10.5414/cpp42543
https://doi.org/10.5414/cpp42543
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 444:421-426
In previous studies, an analytically well-defined senna extract, commonly used as a laxative, gave positive responses in vitro in the Ames test and in the CHO assay. Therefore, the objective of this study was to investigate the genotoxic activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f491ae7ae91ef1ca0b310190c9b14d95
https://doi.org/10.1016/s1383-5718(99)00115-1
https://doi.org/10.1016/s1383-5718(99)00115-1
Autor:
G. Krumbiegel, H.U. Schulz
Publikováno v:
Pharmacology. 47:120-124
Therapeutic doses of two laxatives (Agiolax and Sennatin) were repeatedly administered to 10 healthy volunteers in a two-way change-over design. Blood samples were collected up to 96 h after the first dose, and plasma levels of total aloe-emodin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931b6ab3abf3dccfd96fd94b7fe387c2
https://doi.org/10.1159/000139850
https://doi.org/10.1159/000139850
Publikováno v:
Ciba Foundation Symposium 97-Better Crops for Food
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76245ec4bfe848c3498b9bca3d2bcced
https://doi.org/10.1002/9780470720783.ch15
https://doi.org/10.1002/9780470720783.ch15
Publikováno v:
Phytopharmaka V ISBN: 9783642636936
Silymarin, a purified extract from Silybum marianum, is the active principle in several hepatoprotective drugs. It is chemically well defined and consists mainly of four flavonoid isomers (approx. 80 %). Among these silibinin is the most abundant (Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::018c775f720ed8f552fa393233de5aa8
https://doi.org/10.1007/978-3-642-58709-2_9
https://doi.org/10.1007/978-3-642-58709-2_9
Publikováno v:
Mutation research. 393(3)
The study was performed to investigate the potential of emodin (1,3,8-trihydroxy-6-methylanthraquinone) to induce micronuclei in polychromatic erythrocytes (PCEs). Mice of both genders received a single oral dose of 2000 mg emodin/kg and were killed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebfc20cb5736752249dc588c8e14abb
https://pubmed.ncbi.nlm.nih.gov/9393621
https://pubmed.ncbi.nlm.nih.gov/9393621
Publikováno v:
Journal of chromatography. B, Biomedical applications. 670(2)
A combination of two stereoselective assays was developed using column-switching HPLC with electrochemical detection for the determination of free (unconjugated) silibinin and RP-HPLC with UV detection for the measurement of total (free and conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be4e46de60fbf28b68a77c04649f52b
https://pubmed.ncbi.nlm.nih.gov/8548017
https://pubmed.ncbi.nlm.nih.gov/8548017
Publikováno v:
Arzneimittel-Forschung. 45(1)
Seven silymarin products (pharmacies only), two of them with two batches each, were analysed for their ingredients, in particular silibinin (CAS 22888-70-6) and tested in vitro for their liberation of active agents. Founded on the results of these te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f8048e139251c9beae52128dc613c6b
https://pubmed.ncbi.nlm.nih.gov/7893272
https://pubmed.ncbi.nlm.nih.gov/7893272
Autor:
W. Voderholzer, I. Winblad, E.G. Hahn, P.G. Flanagan, B. Schneider, T. Frieling, K. Geboes, A. Van Damme, Chantal Dupuy, Joseph Lemli, P. Koistinen, A.P. Passmore, M.G. Scott, A. Schirgi-Degen, C. Rupprecht, P. Sjöberg, S. Müller-Lissner, A. Lydén-Sokolowski, S.A. Müller-Lissner, Masao Hattori, Stefan A. Müller-Lissner, G. Nijs, Klaus Witthohn, J. Siemers, C. Stoker, Wilson Davies, J.D. Wood, M. Schemann, Kyoichi Kobashi, B. Ueberschaer, Tove Lynn Farbrot, G. Baretton, K. Ewe, Jan Schuurkes, N.W. Read, Wolf Grimminger, Kunhua Fan, J. Kusche, O. Kinnunen, Tone Junker, Karl Egil Malterud, A.G. Klauser, J.E. Lennard-Jones, K.P.J. Geboes, H.G. Miltenburger, Angelo A. Izzo, C. Spiessens, E. Beubler, G. Müller, R.D.E. Rumsey, A. Heidemann, Amnon Sonnenberg, Karel Geboes, G. Franz, K.P. Odenthal, G. Krumbiegel, T. Yagi, Martin Lipkin, E. Leng-Peschlow, A. Nilsson, Elke Leng-Pescklow, G. Nusko, Nicola Mascolo, K. Yamauchi, Reidar Bredo Sund, H.U. Schulz, R.L. Rudolph, S. Kuwano, Anne Elisabeth Huse, Elke Leng-Peschlow, Peter de Witte, J. Salokannel, Lionel Bueno, Werner Lang, P.E. Squires, Astrid D. Müller, Kan Yang, Ann Meulemans, Teruaki Akao, C.-P. Siegers, Jean Fioramonti, Francesco Capasso, Tsuneo Namba, Giuseppina Autore, A.G. Press, Ulrich Mengs, U. Mengs, Giulia Di Carlo, P. De Witte
Publikováno v:
Pharmacology. 47:262-262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ca145cee1a9c3dc4411bd4cf9e97b9e
https://doi.org/10.1159/000139870
https://doi.org/10.1159/000139870