Zobrazeno 1 - 10
of 144
pro vyhledávání: '"G Kapp"'
Autor:
Vanessa F. Schmidt, Friedrich G. Kapp, Constantin Goldann, Linda Huthmann, Beatrix Cucuruz, Richard Brill, Veronika Vielsmeier, Caroline T. Seebauer, Armin‐Johannes Michel, Max Seidensticker, Wibke Uller, Jakob B. W. Weiß, Alena Sint, Beate Häberle, Julia Haehl, Alexandra Wagner, Johanna Cordes, Annegret Holm, Denny Schanze, Jens Ricke, Melanie A. Kimm, Walter A. Wohlgemuth, Martin Zenker, Moritz Wildgruber
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background We aimed to correlate alterations in the rat sarcoma virus (RAS)/mitogen‐activated protein kinase pathway in vascular anomalies to the clinical phenotype for improved patient and treatment stratification. Methods and Results This retrosp
Externí odkaz:
https://doaj.org/article/f9b209d81147469d8e7949fb0fe3e887
Autor:
Anne Dompmartin, Eulalia Baselga, Laurence M. Boon, Andrea Diociaiuti, Veronika Dvorakova, May El Hachem, Paolo Gasparella, Emir Haxhija, Nader Ghaffarpour, Kristiina Kyrklund, Alan D. Irvine, Friedrich G. Kapp, Jochen Rößler, Päivi Salminen, Caroline van den Bosch, Carine van der Vleuten, Leo Schultze Kool, Miikka Vikkula
Publikováno v:
Journal of Vascular Anomalies, Vol 4, Iss 2, p e064 (2023)
Objective(s):. To elaborate expert consensus patient pathways to guide patients and physicians toward efficient diagnostics and management of patients with venous malformations. Methods:. VASCERN-VASCA (https://vascern.eu/) is a European network of m
Externí odkaz:
https://doaj.org/article/c0e5da68d8ac422abba0cd40b9c4244d
Autor:
Pravin Kumar Ankush Jagtap, Tomáš Kubelka, Komal Soni, Cindy L. Will, Divita Garg, Claudia Sippel, Tobias G. Kapp, Harish Kumar Potukuchi, Kenji Schorpp, Kamyar Hadian, Horst Kessler, Reinhard Lührmann, Felix Hausch, Thorsten Bach, Michael Sattler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
So far only a few compounds have been reported as splicing modulators. Here, the authors combine high-throughput screening, chemical synthesis, NMR, X-ray crystallography with functional studies and develop phenothiazines as inhibitors for the U2AF H
Externí odkaz:
https://doaj.org/article/816cddccf4d4425e993bdca998fb63bd
Autor:
Friedrich G. Kapp, Cedric Schneider, Annegret Holm, Hannah Glonnegger, Charlotte M. Niemeyer, Jochen Rößler, Barbara Zieger
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1840 (2022)
Background: Vascular anomalies comprise a diverse group of rare diseases with altered blood flow and are often associated with coagulation disorders. The most common example is a localized intravascular coagulopathy in venous malformations leading to
Externí odkaz:
https://doaj.org/article/da67aa4bdad24e0ab7bb4b09fc3900fd
Autor:
Annegret Holm, Maroeska te Loo, Leo Schultze Kool, Päivi Salminen, Veronica Celis, Eulalia Baselga, Sophie Duignan, Veronika Dvorakova, Alan D. Irvine, Laurence M. Boon, Miikka Vikkula, Nader Ghaffarpour, Charlotte M. Niemeyer, Jochen Rössler, Friedrich G. Kapp
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Extensive lymphatic malformations (LMs) of the head and neck region may require tracheostomy to secure the airway. Treatment of these life-threatening LMs is usually multimodal and includes sclerotherapy and surgery, among others. Recently, systemic
Externí odkaz:
https://doaj.org/article/d2180b056612495081196bbb0e757f99
Autor:
Margret Schottelius, Marina Ludescher, Frauke Richter, Tobias G. Kapp, Horst Kessler, Hans-Jürgen Wester
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Background The development and clinical translation of [68Ga] Pentixafor has substantially promoted the relevance of non-invasive PET imaging of CXCR4 expression in a broad spectrum of diseases, including cancer and inflammation. Its pronoun
Externí odkaz:
https://doaj.org/article/e89eed2cb3c34ab1a5ef058faafa039c
Autor:
Indre Piragyte, Thomas Clapes, Aikaterini Polyzou, Ramon I. Klein Geltink, Stylianos Lefkopoulos, Na Yin, Pierre Cauchy, Jonathan D. Curtis, Lhéanna Klaeylé, Xavier Langa, Cora C. A. Beckmann, Marcin W. Wlodarski, Patrick Müller, Dominic Van Essen, Angelika Rambold, Friedrich G. Kapp, Marina Mione, Joerg M. Buescher, Erika L. Pearce, Alexander Polyzos, Eirini Trompouki
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
HLX transcription factor regulates haematopoietic stem and progenitor cell (HSPC) differentiation and is overexpressed in acute myeloid leukemia. Here the authors show that HLX overexpression leads to myeloid differentiation block in zebrafish and hu
Externí odkaz:
https://doaj.org/article/6e1870de09fa401dacacea3d50a2697e
Publikováno v:
Australian Forestry. 85:116-132
Autor:
Themis-Areti A. Andreoti, Sebastian Berg, Annegret Holm, Marina Angerer, Michael Oberlin, Etelka Foeldi, Iris Baumgartner, Charlotte M. Niemeyer, Jochen Rössler, Friedrich G. Kapp
Publikováno v:
Lymphatic Research and Biology.
Objective: Generalized lymphatic anomaly (GLA), Gorham-Stout disease (GSD), kaposiform lymphangiomatosis (KLA), and central conducting lymphatic anomaly (CCLA) are rare, multisystem lymphatic disorders, referred to as complex lymphatic anomalies (CLA
Autor:
Jakob Siebert, Michaela Schneider, Daniela Reuter‐Schmitt, Julia Würtemberger, Annette Neubüser, Wolfgang Driever, Simone Hettmer, Friedrich G. Kapp
Publikováno v:
Pediatric Blood & Cancer. 70
Rhabdomyosarcomas (RMS) are the most common pediatric soft tissue sarcomas. High-risk and metastatic disease continues to be associated with very poor prognosis. RMS model systems that faithfully recapitulate the human disease and provide rapid, cost