Zobrazeno 1 - 10
of 75
pro vyhledávání: '"G K Jacobsen"'
Autor:
N E Skakkebaek, Kristian Almstrup, A. Jørgensen, Thomas Horn, Inge A. Olesen, H. Leffers, J E Nielsen, David Møbjerg Kristensen, E. Rajpert-De Meyts, G K Jacobsen
Publikováno v:
Andrologia. 44:78-85
Prompted by the recently reported expression of POU5F1 (OCT3/4) in epididymis, a panel of markers for carcinoma in situ (CIS) testis and testicular germ cell tumours (TGCT), including AP-2γ(TFAP2C), NANOG, OCT3/4, KIT, placental-like alkaline phosph
Autor:
Indira B. Taylor, Ruth M. S. Hansen, Andrew O.M. Wilkie, G K Jacobsen, Anne Goriely, Inge A. Olesen, Simon J. McGowan, Gilean McVean, Susanne P. Pfeifer, Ewa Rajpert-De Meyts
Publikováno v:
Nature genetics
Genes mutated in congenital malformation syndromes are frequently implicated in oncogenesis, but the causative germline and somatic mutations occur in separate cells at different times of an organism's life. Here we unify these processes to a single
Autor:
Birgit Guldhammer Skov, Asger Dirksen, Mark Krasnik, Peter Vilmann, Ulrik Lassen, Paul Frost Clementsen, G. K. Jacobsen, Niels Maltbaek, Soeren S. Larsen
Publikováno v:
Lung Cancer. 49:377-385
Summary Background: Up to 45% of operations with curative intent for non-small-cell lung cancer (NSCLC) can be regarded as futile, apparently because the stage of the disease is more advanced than expected preoperatively. During the past decade sever
Autor:
Mark Krasnik, Paul Frost Clementsen, Birgit Guldhammer Skov, Peter Vilmann, Soeren S. Larsen, Asger Dirksen, G. K. Jacobsen
Publikováno v:
Lung Cancer. 48:85-92
Exact mediastinal evaluation of patients with non-small-cell lung cancer (NSCLC) is mandatory to improve selection of resectable and curable patients for surgery. Mediastinoscopy (MS) and endoscopic ultrasound guided fine needle aspiration biopsy (EU
Autor:
Florence Aubry, Jiri Bartek, Michel Samson, N E Skakkebaek, E. Rajpert-De Meyts, G K Jacobsen, J Bartkova
Publikováno v:
Histopathology. 42:217-226
Aims: Spermatocytic seminoma is a rare germ cell derived tumour of the testis that occurs mainly in older men. We analysed the expression of recently discovered markers for germ cell differentiation and the mitosis–meiosis transition in order to de
Autor:
G K Jacobsen, Sébastien Henno, Ewa Rajpert-De Meyts, Nathalie Rioux-Leclercq, Bernard Jégou, Laurence Olivo, Anne-Pascale Satie, Giulio C. Spagnoli, Michel Samson
Publikováno v:
Laboratory Investigation. 82:775-780
Cancer/testis genes are potential targets for therapeutic genetic and immunologic approaches, and are highly expressed in a large variety of human cancers. However, they are not expressed in normal tissues, with the exception of the testis. The NY-ES
Autor:
K Folke, Søren S. Larsen, Jesper Holst Pedersen, Mark Krasnik, P Faurschou, G. K. Jacobsen, Peter Vilmann
Publikováno v:
Thorax. 57:98-103
Background: A study was undertaken to evaluate the clinical impact of endoscopic ultrasound guided fine needle aspiration biopsy (EUS-FNA) in patients with mediastinal masses suspected of malignancy. Methods: From April 1993 to December 1999, 84 pati
Publikováno v:
Revista Portuguesa de Pneumologia, Vol 10, Iss 2, Pp 173-175 (2004)
RESUMO: O correcto estadiamento do cancro do pulmão é fundamental, não só na determinação do prognóstico mas também na orientação terapêutica.A avaliação da extensão tumoral ao mediastino, por invasão directa ou metastática ganglionar
Autor:
A. Nalla, M. N. Møller, H. J. Nielsen, T. Bøg-Hansen, Jens Thomsen, Per Cayé-Thomasen, G. K. Jacobsen, L. Baandrup, S.-E. Stangerup, K. Werther
Publikováno v:
Journal of Neurological Surgery Part B: Skull Base. 73
Autor:
Ewa Rajpert-De Meyts, Kristian Almstrup, Olga Mlynarska, John E. Nielsen, Dina G. Kristensen, G K Jacobsen
Publikováno v:
Cancer genetics. 205(9)
Testicular spermatocytic seminoma (SS) is a rare tumor type predominantly found in elderly men. It is thought to originate from spermatogonia and shows cytological and genetic heterogeneity. In this study, we performed for the first time a comprehens