Výsledky vyhledávání - "G K, Singhera"

Effect of Therapeutics on the Modulation of ACE2 Expression in Airway Epithelium: Implications for COVID-19

Autor: Don D. Sin, G. K. Singhera, T. Guo, Janice M. Leung, Delbert R. Dorscheid

Publikováno v: TP3. TP003 COVID-19 INFECTIONS, MECHANISMS, AND CLINICAL IMPLICATIONS.

RATIONALE: Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute respiratory syndrome coronavirus (SARS-CoV2). SARS-CoV-2 uses the receptor angiotensin-converting enzyme 2 (ACE2) to gain entry to host cells in the respirator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::724c798d6907cd01b25a2346c2f91424
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1283

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Sialyl Lewis X modification of the epidermal growth factor receptor regulates receptor function during airway epithelial wound repair

Autor: S, Allahverdian, A, Wang, G K, Singhera, B W, Wong, D R, Dorscheid

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 40(4)

Epidermal growth factor receptor (EGFR) is a major regulator of airway epithelial cell (AEC) functions such as migration, proliferation and differentiation, which play an essential role in epithelial repair. EGFR is a glycoprotein with 12 potential N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a87581e44b63717efc637abcb683b46
https://pubmed.ncbi.nlm.nih.gov/20447077

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