Zobrazeno 1 - 10
of 50
pro vyhledávání: '"G K, Rivera"'
Publikováno v:
Blood. 82:889-894
The CD34 antigen was detected on > or = 10% of the blast cells in 235 (70%) of 335 cases of newly diagnosed childhood acute lymphoblastic leukemia (ALL) treated in two consecutive chemotherapy trials. By immunophenotype, the distribution of positive
Publikováno v:
Blood. 82:576-580
Sequential analysis of blast cell chromosomes in 98 cases of acute lymphoblastic leukemia (ALL) disclosed entirely different karyotypes for nine patients at the time of relapse. The presenting clinical, immunophenotypic, and cytogenetic features of t
Publikováno v:
Blood. 81:602-609
Children with acute lymphoblastic leukemia (ALL) who have completed 2.5 to 3 years of initial chemotherapy have an off-therapy relapse rate of approximately 20%. In an attempt to improve the survival of children with a late bone marrow (BM) relapse (
Publikováno v:
Blood. 79:3245-3252
Among ploidy groups in childhood acute lymphoblastic leukemia (ALL), hyperdiploidy 47 to 50 is perhaps the least well known. From December 1979 to December 1990, we successfully studied banded karyotypes in 598 cases of newly diagnosed ALL, of which
Autor:
C H, Pui, F G, Behm, B, Singh, M J, Schell, D L, Williams, G K, Rivera, D K, Kalwinsky, J T, Sandlund, W M, Crist, S C, Raimondi
Publikováno v:
Blood. 75:174-179
Presenting features of 120 consecutive children with T-cell acute lymphoblastic leukemia (ALL), representing 15% of all patients diagnosed as having ALL during the study period, were analyzed to determine relationships with treatment outcome. Patient
Autor:
G R, Buchanan, G K, Rivera, B H, Pollock, J M, Boyett, A R, Chauvenet, H, Wagner, D A, Maybee, W M, Crist, D, Pinkel
Publikováno v:
Cancer. 88(5)
Children with acute lymphoblastic leukemia (ALL) who experience hematologic recurrence while receiving chemotherapy or within 6 months after its cessation have a low cure rate. In this study (Pediatric Oncology Group Protocol 8303) two methods were e
Autor:
M H, Woo, M V, Relling, D S, Sonnichsen, G K, Rivera, C B, Pratt, C H, Pui, W E, Evans, A S, Pappo
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(3)
Clearance of anticancer drugs in children is highly variable, leading to wide variability in the systemic exposure associated with each dosage escalation in Phase I studies. The purpose of this Phase I study was to escalate targeted systemic exposure
Autor:
C H, Pui, H H, Mahmoud, G K, Rivera, M L, Hancock, J T, Sandlund, F G, Behm, D R, Head, M V, Relling, R C, Ribeiro, J E, Rubnitz, L E, Kun, W E, Evans
Publikováno v:
Blood. 92(2)
Central nervous system (CNS) relapse has been an obstacle to uniformly successful treatment of childhood acute lymphoblastic leukemia (ALL) for many years. We therefore intensified intrathecal chemotherapy (simultaneously administered methotrexate, h
Autor:
S C, Raimondi, S A, Shurtleff, J R, Downing, J, Rubnitz, S, Mathew, M, Hancock, C H, Pui, G K, Rivera, G C, Grosveld, F G, Behm
Publikováno v:
Blood. 90(11)
Although abnormalities involving the short arm of chromosome 12 (12p) are one of the most frequently observed rearrangements in childhood acute lymphoblastic leukemia (ALL), little is known about the frequency of different structural abnormalities an
Autor:
C L, Chen, Q, Liu, C H, Pui, G K, Rivera, J T, Sandlund, R, Ribeiro, W E, Evans, M V, Relling
Publikováno v:
Blood. 89(5)
The genetic polymorphisms in human glutathione S-transferases (GST) M1 and T1 have been associated with race, disease risk, and outcome of some adult cancers. Also, there are racial differences in the incidence and characteristics of childhood acute