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pro vyhledávání: '"G K, Mumford"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
Abecarnil, a novel beta-carboline, is under development for the treatment of Generalized Anxiety Disorder. This study compared the behavioral, subjective and reinforcing effects of abecarnil to those of the benzodiazepine alprazolam in 14 healthy mal
Publikováno v:
JAMA. 272(13)
The extent to which daily caffeine use is associated with a substance dependence syndrome similar to that associated with other psychoactive drugs is unknown. The purpose of this study was to assess volunteers who reported problems with their use of
Autor:
G K, Mumford, S G, Holtzman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(3)
Caffeine engenders qualitatively different subjective effects in humans at low and high doses. Low doses of caffeine are mildly reinforcing and produce psychomotor stimulation. High doses of caffeine can produce subjective feelings of anxiety, dyspho
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 244(1)
The effect of surgical denervation on alpha-1 adrenergic receptor-stimulated inositol phosphate (IP) formation was examined in rat vas deferens. Rings of tissue from acutely reserpinized animals were incubated with [3H]inositol in the presence of lit