Zobrazeno 1 - 10
of 61
pro vyhledávání: '"G K, Haines"'
Autor:
G. K. Haines, James A. Radosevich, Benjamin J. Vesper, Abdullah Onul, Michael B. Altman, Kim M. Elseth, John C. Roeske, William A. Paradise, Gabor Tarjan, H. De Vitto, Bulent Aydogan, Jiaping Xue
Publikováno v:
Tumor Biology. 34:203-214
There is a lack of understanding of the casual mechanisms behind the observation that some breast adenocarcinomas have identical morphology and comparatively different cellular growth behavior. This is exemplified by a differential response to radiat
Autor:
David B. Conley, Paul R. Yarnold, Leslie Grammar, Robert C. Kern, Pete S. Batra, Anne Marie Ditto, Anju Tripathi, G. K. Haines
Publikováno v:
The Laryngoscope. 113:1703-1706
To investigate the efficacy of endoscopic sinus surgery (ESS) in the management of chronic sinusitis and asthma in patients with nasal polyps and steroid-dependent asthma.Retrospective chart review.The study included 17 patients who underwent ESS wit
Publikováno v:
The Laryngoscope. 114:279-285
Objective: The pathology of the olfactory mucosa is poorly understood; however, most cases of hyposmia and anosmia appear to be associated with a decline in the number of functioning mature olfactory sensory neurons (OSNs). Under normal conditions, O
Autor:
Mohammad A. Amin, Alisa E. Koch, Pei-Suen Tsou, G. K. Haines, Gautam Edhayan, Jeffrey H. Ruth, Phillip L. Campbell, Christine M. Ha, Takeo Isozaki
Publikováno v:
Arthritis Research & Therapy
Introduction We previously reported that sialyl Lewisy, synthesized by fucosyltransferases, is involved in angiogenesis. Fucosyltransferase 1 (fut1) is an α(1,2)-fucosyltransferase responsible for synthesis of the H blood group and Lewisy antigens.
Autor:
Kenneth J. Katschke, Matthew A. Connors, Michael V. Volin, G K Haines, Alisa E. Koch, Mohammad A. Amin, Hirokazu Kurata, D C Woodruff, Ken-ichi Arai, Pawan Kumar, James M. Woods, Jeffrey H. Ruth
Publikováno v:
The Journal of Immunology. 166:1214-1222
IL-4 is a cytokine with anti-inflammatory properties on activated macrophages. Rheumatoid arthritis, an autoimmune inflammatory disease, is characterized by a paucity of IL-4 and an abundance of synovial macrophage-derived mediators. Herein, the effe
Autor:
Marc A. Webster, Giorgio Inghirami, Robert J. Stenger, Roger J. Davis, G K Haines, Genichi Watanabe, William J. Muller, Chris Albanese, Richard T. Lee, Richard G. Pestell, Joan S. Brugge
Publikováno v:
Journal of Biological Chemistry. 274:7341-7350
The cyclin D1 gene is overexpressed in breast tumors and encodes a regulatory subunit of cyclin-dependent kinases that phosphorylate the retinoblastoma protein. pp60c-src activity is frequently increased in breast tumors; however, the mechanisms gove
Publikováno v:
Journal of Clinical Pathology. 50:314-319
AIM: To determine whether the urokinase plasminogen activator receptor (u-PAR; CD87) exhibits a possible pathogenic role in rheumatoid and osteoarthritis. METHODS: A semiquantitative, indirect immunoperoxidase histochemical analysis was performed on
Autor:
A E Koch, S L Kunkel, M R Shah, S Hosaka, M M Halloran, G K Haines, M D Burdick, R M Pope, R M Strieter
Publikováno v:
The Journal of Immunology. 155:3660-3666
Leukocyte recruitment is critical in the inflammation seen in rheumatoid arthritis (RA). To determine whether the chemokine growth-related gene product alpha (gro alpha) plays a role in this process, we examined synovial tissue (ST), synovial fluid (
Autor:
Lisa A. Harlow, S J Lin, Rebekah Fu, Manisha R. Shah, Alisa E. Koch, Timothy W. Fong, G K Haines, G Rayan, Zoltán Szekanecz
Publikováno v:
Clinical Immunology and Immunopathology. 76:187-194
The ingress of inflammatory cells into the rheumatoid (RA) synovial tissue (ST) plays a role in the pathogenesis of this disease. Transforming growth factor beta (TGF-beta) may play a role in this process. We have investigated the distribution of end
Publikováno v:
The Journal of Immunology. 152:4149-4156
Angiogenesis is important in the proliferation of inflammatory synovial tissue. Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that is also angiogenic in vivo. We examined the potential role of VEGF in mediating chemotaxis a