Zobrazeno 1 - 10
of 10
pro vyhledávání: '"G J Wiederrecht"'
Autor:
G. J. Wiederrecht, Terence Wagenknecht, Robert A. Grassucci, Sidney Fleischer, J. Berkowitz, Hong-Bo Xin
Publikováno v:
Biophysical Journal. 70(4):1709-1715
A 12-kDa immunophilin (FKBP12) is an integral component of the skeletal muscle ryanodine receptor (RyR). The RyR is a hetero-oligomeric complex with structural formula (FKBP)4(Ryr1)4, where Ryr1 is the 565-kDa product of the Ryr1 gene. To aid in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7168ff9ba49455ae4254be54eb715c
Publikováno v:
Molecular and cellular biology. 15(8)
The immunosuppressive drugs FK506 and cyclosporin A block T-lymphocyte proliferation by inhibiting calcineurin, a critical signaling molecule for activation. Multiple intracellular receptors (immunophilins) for these drugs that specifically bind eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b464ac025090f35b2335c4d29b6535
https://pubmed.ncbi.nlm.nih.gov/7542743
https://pubmed.ncbi.nlm.nih.gov/7542743
Publikováno v:
Progress in cell cycle research. 1
The immunosuppressant drug, rapamycin (RAP), is a potent inhibitor of IL-2-dependent T-cell proliferation. The antiproliferative effect of RAP is mediated through the formation of an active complex with its cytosolic receptor protein, FKBP12. The mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bd92b326afa6f7fc6e0ce0f0a058092
https://pubmed.ncbi.nlm.nih.gov/9552353
https://pubmed.ncbi.nlm.nih.gov/9552353
Autor:
J N, Parsons, G J, Wiederrecht, S, Salowe, J J, Burbaum, L L, Rokosz, R L, Kincaid, S J, O'Keefe
Publikováno v:
The Journal of biological chemistry. 269(30)
The immunosuppressant FK-506 (tacrolimus) forms a complex with a ubiquitous intracellular receptor, FK-506 binding protein (FKBP12), and this complex inhibits the heterodimeric Ca2+/calmodulin-dependent phosphatase, calcineurin, an essential componen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e91db1f4e8698f6ef7885d9c357ff27
https://pubmed.ncbi.nlm.nih.gov/7518461
https://pubmed.ncbi.nlm.nih.gov/7518461
Autor:
G J Wiederrecht, G M Brown
Publikováno v:
Journal of Biological Chemistry. 259:14121-14127
The enzyme system responsible for the conversion of 2-amino-4-oxo-6-(D-erythro-1',2',3'-trihydroxypropyl)-7,8-dihyd roptridine triphosphate (dihydroneopterin triphosphate or H2-NTP) to 2-amino-4-oxo-6-acetyl-7,8-dihydro-3H,9H-pyrimido[4,5-b]-[1,4]dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133813c639e8a8e19cb3f1e9baf17cab
https://doi.org/10.1016/s0021-9258(18)89865-9
https://doi.org/10.1016/s0021-9258(18)89865-9
Publikováno v:
Journal of Biological Chemistry. 256:10399-10402
A compound that is involved in the biosynthesis of the drosopterin eye pigments has been isolated from the heads of Drosophila melanogaster. Analyses of this compound by chemical, mass spectral, and proton nuclear magnetic resonance techniques in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37ad349f396b832bbe13f21bae1463ff
https://doi.org/10.1016/s0021-9258(19)68632-1
https://doi.org/10.1016/s0021-9258(19)68632-1
Publikováno v:
Journal of Biological Chemistry. 259:2195-2200
The compound 2-amino-4-oxo-6-acetyl-7,8-dihydro-3H,9H-pyrimido[4,5-b]-[1,4]diazepine (pyrimidodiazepine or PDA, for short) is a precursor of the red eye pigments called the drosopterins in Drosophila melanogaster. The precursor of PDA is 2-amino-4-ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a06073e50056db9a529226e91d5176fb
https://doi.org/10.1016/s0021-9258(17)43337-0
https://doi.org/10.1016/s0021-9258(17)43337-0
Autor:
G J, Wiederrecht, G M, Brown
Publikováno v:
The Journal of biological chemistry. 259(22)
The enzyme system responsible for the conversion of 2-amino-4-oxo-6-(D-erythro-1',2',3'-trihydroxypropyl)-7,8-dihyd roptridine triphosphate (dihydroneopterin triphosphate or H2-NTP) to 2-amino-4-oxo-6-acetyl-7,8-dihydro-3H,9H-pyrimido[4,5-b]-[1,4]dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae8705519718f5aa1ed9a980588e14d6
https://pubmed.ncbi.nlm.nih.gov/6438092
https://pubmed.ncbi.nlm.nih.gov/6438092
Publikováno v:
The Journal of biological chemistry. 259(4)
The compound 2-amino-4-oxo-6-acetyl-7,8-dihydro-3H,9H-pyrimido[4,5-b]-[1,4]diazepine (pyrimidodiazepine or PDA, for short) is a precursor of the red eye pigments called the drosopterins in Drosophila melanogaster. The precursor of PDA is 2-amino-4-ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b04a8e045481586e0395c3b48617d3d
https://pubmed.ncbi.nlm.nih.gov/6421807
https://pubmed.ncbi.nlm.nih.gov/6421807
Publikováno v:
The Journal of biological chemistry. 256(20)
A compound that is involved in the biosynthesis of the drosopterin eye pigments has been isolated from the heads of Drosophila melanogaster. Analyses of this compound by chemical, mass spectral, and proton nuclear magnetic resonance techniques in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d192041821a6b6768b73c800964fb78f
https://pubmed.ncbi.nlm.nih.gov/6793578
https://pubmed.ncbi.nlm.nih.gov/6793578