Zobrazeno 1 - 10
of 43
pro vyhledávání: '"G J Fisher"'
Autor:
F, Wang, N, Smith, L, Maier, W, Xia, C, Hammerberg, H, Chubb, C, Chen, M, Riblett, A, Johnston, J E, Gudjonsson, Y, Helfrich, S, Kang, G J, Fisher, J J, Voorhees
Publikováno v:
The British journal of dermatology. 167(1)
Psoriasis is a Th17/Th1-mediated skin disease that often responds to antitumour necrosis factor (TNF)-α therapies, such as etanercept.To better define mechanisms by which etanercept improves psoriasis and to gain insight into disease pathogenesis.We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f26a83ded0c666cc27a637b7827d8446
https://pubmed.ncbi.nlm.nih.gov/22458549
https://pubmed.ncbi.nlm.nih.gov/22458549
Autor:
Patricia A. Henderson, James T. Elder, G. J. Fisher, N. J. Reynolds, J.J. Voorhees, Joseph J. Baldassare, Harvinder S. Talwar
Publikováno v:
Biochemical Journal. 294:535-544
We have investigated coupling between the epidermal growth factor (EGF) receptor and the phospholipase C (PLC)/protein kinase C (PKC) signal-transduction system in normal skin fibroblasts and keratinocytes, for which EGF and transforming growth facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414ac537cf4512fda2f7b099cdd6d09e
https://doi.org/10.1042/bj2940535
https://doi.org/10.1042/bj2940535
Autor:
Q Y Zhang, C Hammerberg, J J Baldassare, P A Henderson, D Burns, M Ceska, J J Voorhees, G J Fisher
Publikováno v:
The Journal of Immunology. 149:1402-1408
Phorbol ester (TPA) and retinoic acid (RA) are two potent immunomodulatory agents whose actions are mediated through distinct signal transduction pathways involving protein kinase C (PKC) and nuclear RA receptors, respectively. We have investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bdd010a45435e331a7af82b050a879d
https://doi.org/10.4049/jimmunol.149.4.1402
https://doi.org/10.4049/jimmunol.149.4.1402
Publikováno v:
Journal of Biological Chemistry. 267:15585-15590
Human platelets were found by immunoblot analysis to express protein kinase C (PKC) isozymes alpha, beta, delta, and zeta, but not gamma, epsilon, or eta. Exposure of platelets to thrombin, in the presence of 1 mM calcium, induced increased membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38e65c17f828a8c017f3273232421652
https://doi.org/10.1016/s0021-9258(19)49576-8
https://doi.org/10.1016/s0021-9258(19)49576-8
Publikováno v:
Clinics in geriatric medicine. 17(4)
Premature skin aging, or photoaging, results largely from repeated exposure to ultraviolet (UV) radiation from the sun. Photoaging is characterized clinically by wrinkles, mottled pigmentation, rough skin, and loss of skin tone; the major histologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4d6d6c6a1bb675d631f87e17cb8714e
https://pubmed.ncbi.nlm.nih.gov/11535421
https://pubmed.ncbi.nlm.nih.gov/11535421
Publikováno v:
International Journal of Oncology.
Growth factors interact with their cell surface receptors and activate the enzyme PI 3-kinase (PI 3-K) resulting in the formation of 3-phosphorylated phosphatidylinositols, which in turn activate the serine/threonine kinase AKT/PKB. AKT functions, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfe7083125fa107b0a1a58ca07385a2
https://doi.org/10.3892/ijo.18.3.461
https://doi.org/10.3892/ijo.18.3.461
Publikováno v:
Cancer research. 60(8)
Repeated exposure of human skin to solar UV radiation leads to premature aging (photoaging) and skin cancer. UV-induced skin damage can be ameliorated by all-trans retinoic acid treatment. The actions of retinoic acid in skin keratinocytes are mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3df8c40638273e7d59cbd0e11d0e5e13
https://pubmed.ncbi.nlm.nih.gov/10786691
https://pubmed.ncbi.nlm.nih.gov/10786691
Autor:
J, Varani, R L, Warner, M, Gharaee-Kermani, S H, Phan, S, Kang, J H, Chung, Z Q, Wang, S C, Datta, G J, Fisher, J J, Voorhees
Publikováno v:
The Journal of investigative dermatology. 114(3)
Damage to human skin due to ultraviolet light from the sun (photoaging) and damage occurring as a consequence of the passage of time (chronologic or natural aging) are considered to be distinct entities. Photoaging is caused in part by damage to skin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d58f7ade024d1c25f2b4867a84db93f
https://pubmed.ncbi.nlm.nih.gov/10692106
https://pubmed.ncbi.nlm.nih.gov/10692106
Publikováno v:
Photochemistry and photobiology. 69(2)
Solar UV radiation damages human skin, affecting skin tone and resiliency and leading to premature aging (photoaging), the symptoms of which include leathery texture, wrinkles, mottled pigmentation, laxity and sallowness. We propose that photoaging r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48ad523e73a1f271e618868c9686ac5a
https://pubmed.ncbi.nlm.nih.gov/10048311
https://pubmed.ncbi.nlm.nih.gov/10048311
Autor:
G J, Fisher, J J, Voorhees
Publikováno v:
The journal of investigative dermatology. Symposium proceedings. 3(1)
Ultraviolet radiation from the sun damages human skin, resulting in an old and wrinkled appearance. A substantial amount of circumstantial evidence indicates that photoaging results in part from alterations in the composition, organization, and struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88beb107c75591147fe8150c21ad5400
https://pubmed.ncbi.nlm.nih.gov/9732061
https://pubmed.ncbi.nlm.nih.gov/9732061