Zobrazeno 1 - 10
of 11
pro vyhledávání: '"G J Ahmann"'
Autor:
J J Westendorf, G J Ahmann, R J Armitage, M K Spriggs, J A Lust, P R Greipp, J A Katzmann, D F Jelinek
Publikováno v:
The Journal of Immunology. 152:117-128
Myeloma is a neoplasia characterized by the accumulation of malignant plasma cells in the bone marrow. In these studies, we have demonstrated that CD40 is expressed in human myeloma cells and have used a recently established IL-6-dependent myeloma ce
Publikováno v:
Blood. 93(1)
We investigated whether interleukin-1beta (IL-1beta) is differentially expressed in plasma cells from monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) patients because IL-1beta appears to play a major role in the de
Autor:
R, Fonseca, G J, Ahmann, S M, Jalal, G W, Dewald, D R, Larson, T M, Therneau, M A, Gertz, R A, Kyle, P R, Greipp
Publikováno v:
British journal of haematology. 103(3)
Primary systemic amyloidosis (AL) is a plasma cell disorder characterized by deposition of monoclonal light chains in different organ systems. Although multiple and complex numerical chromosomal abnormalities have been described in patients with mult
Publikováno v:
Cytometry. 26(2)
Bone marrow plasma cells (PC) from patients with multiple myeloma (MM) express monoclonal cytoplasmic immunoglobulin (clg) light chain, strongly express CD38, and usually lack or dimly express CD45. The detection of malignant plasma cells in the peri
Publikováno v:
Leukemia. 10(5)
A consensus regarding myeloma cell growth factor responsiveness and ability to produce autocrine interleukin (IL)-6 has not yet been obtained. In this study, we have established three new human myeloma cell lines (DP-6, KAS-6/1 and KP-6) from patient
Autor:
J J, Westendorf, G J, Ahmann, J A, Lust, R C, Tschumper, P R, Greipp, J A, Katzmann, D F, Jelinek
Publikováno v:
Current topics in microbiology and immunology. 194
Autor:
J J, Westendorf, G J, Ahmann, R J, Armitage, M K, Spriggs, J A, Lust, P R, Greipp, J A, Katzmann, D F, Jelinek
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(1)
Myeloma is a neoplasia characterized by the accumulation of malignant plasma cells in the bone marrow. In these studies, we have demonstrated that CD40 is expressed in human myeloma cells and have used a recently established IL-6-dependent myeloma ce
Autor:
R Fonseca, Esteban Braggio, Jonathan J Keats, P L Bergsagel, Alexander Keith Stewart, J. Mantei, G. J. Ahmann
Publikováno v:
Journal of Clinical Oncology. 29:8024-8024
8024 Background: Multiple myeloma (MM) is characterized by a remarkable heterogeneity in outcome following standard and high-dose therapies. In MM, gene expression profiling (GEP) has a key role in...
Autor:
D F, Jelinek, G J, Ahmann, P R, Greipp, S M, Jalal, J J, Westendorf, J A, Katzmann, R A, Kyle, J A, Lust
Publikováno v:
Cancer research. 53(21)
A new human myeloma cell line, ANBL-6, was established and characterized at the genotypic and phenotypic levels. The cells exhibit a clonally rearranged immunoglobulin gene locus and resemble plasma cells morphologically. The ANBL-6 cells also exhibi
Autor:
Kim Henderson, P R Greipp, G. J. Ahmann, Susanna Jacobus, Michael E. Williams, R Fonseca, S V Rajkumar, David S. Siegel, Natalie S. Callander, S Van Wier
Publikováno v:
Journal of Clinical Oncology. 28:10546-10546
10546 Background: Risk stratification using fluorescent in situ hybridization (FISH) has proven valuable in multiple myeloma (MM). More specifically, three markers have been established as conferring adverse clinical outcome: t(4;14)(p16;q32), t(14;1