Výsledky vyhledávání - "G J, ten Bosch"

A BCR-ABL oncoprotein p210b2a2 fusion region sequence is recognized by HLA-DR2a restricted cytotoxic T lymphocytes and presented by HLA-DR matched cells transfected with an Ii(b2a2) construct

Autor: G J, ten Bosch, J H, Kessler, A M, Joosten, A A, Bres-Vloemans, A, Geluk, B C, Godthelp, J, van Bergen, C J, Melief, O C, Leeksma

Publikováno v: Blood. 94(3)

Peptides corresponding to the fusion site in 210 kD BCR-ABL protein b3a2 (p210b3a2) were previously shown to bind to several HLA class I and II alleles. We have found that b3a2 peptide-specific CD4-positive T-helper cells were able to recognize p210b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c91804846b6e9298fc72c73852852c8
https://pubmed.ncbi.nlm.nih.gov/10419896

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BCR-ABL oncoprotein is expressed by platelets from CML patients and associated with a special pattern of CrkL phosphorylation

Autor: G J, ten Bosch, J H, Kessler, J, Blom, A M, Joosten, C, Gambacorti-Passerini, C J, Melief, O C, Leeksma

Publikováno v: British journal of haematology. 103(4)

Constitutive tyrosine phosphorylation of CrkL was recently demonstrated in platelets from chronic myelogenous leukaemia (CML) patients but BCR-ABL tyrosine kinase could not be detected in the platelet lysates. We studied platelets from 14 CML patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d43d9956ecc036038f2b15274b20d4c0
https://pubmed.ncbi.nlm.nih.gov/9886328

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Recognition of peptides corresponding to the joining region of p210BCR-ABL protein by human T cells

Autor: G J, ten Bosch, A C, Toornvliet, T, Friede, C J, Melief, O C, Leeksma

Publikováno v: Leukemia. 9(8)

In chronic myeloid leukemia (CML) the proto-oncogene c-abl from chromosome 9 q34 is translocated to the breakpoint cluster region (bcr) gene on chromosome 22 q11. This translocation results in a BCR-ABL fusion gene, which encodes chimeric fusion onco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c35696b6b6fbf524536516e26035024
https://pubmed.ncbi.nlm.nih.gov/7643623

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The role of splenectomy in the treatment of relapsing thrombotic thrombocytopenic purpura

Autor: G A, Veltman, A, Brand, O C, Leeksma, G J, ten Bosch, J H, van Krieken, E, Briët

Publikováno v: Annals of hematology. 70(5)

Thrombotic thrombocytopenic purpura (TTP) is a serious disorder of unknown etiology. Clinical findings are the result of vascular occlusions by platelet aggregates. Treatment with plasma exchange, often used in combination with corticosteroids, vincr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::82f915c2425762b44377616a03db0ad7
https://pubmed.ncbi.nlm.nih.gov/7599284

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