Zobrazeno 1 - 10
of 17
pro vyhledávání: '"G J, Vosika"'
Publikováno v:
Molecular biotherapy. 2(1)
A new lipophilic immunomodulator, disaccharide tripeptide glycerol dipalmitoyl (DTP-GDP), has been synthesized and evaluated for its immunologic activity and toxicology. DTP-GDP alone or in liposomes is more effective as an adjuvant and in activating
Publikováno v:
Cancer. 44(2)
The clinical efficacy of intralesional immunotherapy utilizing Mycobacterium smegmatis cell wall skeleton (CWS) and trehalose dimycolate attached to oil droplets was investigated in 15 patients with advanced malignant melanoma. Patients received 300
Autor:
G J, Vosika, K, Briscoe, R W, Carey, J F, O'Donnell, M C, Perry, D, Budman, F, Richards, M, Coleman
Publikováno v:
Cancer treatment reports. 65(9-10)
A phase II study of diglycoaldehyde was conducted in 42 patients with malignant melanoma and soft tissue sarcoma. All patients received diglycoaldehyde at a dose of 2 g/m2 iv over 6 hours daily for 3 days. This was repeated every 28 days. Major toxic
Autor:
D F, Chiuten, G J, Vosika, M T, Shaw, M, Boiron, C, Gisselbrecht, M, Marty, G, Higgins, F M, Muggia
Publikováno v:
Anticancer research. 1(2)
All Phase II studies with diglycoaldehyde with leukemia and solid tumors have been reviewed. The dose schedules employed ranged from 1.5 to 2.0 g/m2/day for 3 to 5 days. The most common side effects have been gastrointestinal (nausea and vomiting), w
Publikováno v:
Cancer. 45(6)
The effectiveness of hypophysectomy and tamoxifen in treating advanced breast cancer was compared in a randomized study of 26 patients who had responded to prior oophorectomy or additive hormonal therapy. When patients failed to respond or relapsed f
Autor:
G J, Vosika, G R, Gray
Publikováno v:
Cancer treatment reports. 67(9)
A phase I study to determine the toxicity and immunologic effects of iv administered aqueous suspensions of mycobacterial cell wall skeleton (CWS) and CWS combined with trehalose dimycolate (TDM) was performed. A total of 26 patients received suspens
Autor:
G J, Vosika
Publikováno v:
Minnesota medicine. 62(7)
Autor:
N J, Vogelzang, R C, Trowbridge, D H, Frenning, A, Theologides, B J, Kennedy, D R, Kelly, S L, Ewing, G J, Vosika
Publikováno v:
Cancer treatment reports. 64(8-9)
Forty consecutive patients with small cell bronchogenic carcinoma were treated. The first 18 patients were treated with CCNU and doxorubicin (Adriamycin) (CA). The next 22 patients were treated with CCNU, doxorubicin, procarbazine, and vincristine (C
Publikováno v:
American journal of clinical oncology. 5(1)
Twenty-seven patients with advanced bronchogenic carcinoma were treated with vindesine, 3 mg/m2/week. Twenty-three patients were evaluable for response. Two of six patients with small-cell carcinoma and one of 17 patients with non-small-cell carcinom
Publikováno v:
American journal of clinical oncology. 6(5)
Sixteen patients, 13 of whom had received prior chemotherapy, were treated with vindesine for advanced malignant melanoma. Previous treatment included vinca alkaloids in six. Thirteen patients received vindesine, 4 mg/m2 and three received vindesine,