P906: IXAZOMIB, DARATUMUMAB AND LOW DOSE DEXAMETHASONE IN FRAIL PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA (NDMM): RESULTS OF THE MAINTENANCE TREATMENT OF THE PHASE II HOVON 143 STUDY

Autor: K. Groen, M. Seefat, K. Nasserinejad, C. A. Stege, E. van der Spek, Y. M. Bilgin, A. Kentos, M. Sohne, R. J. van Kampen, I. Ludwig, N. Thielen, N. Durdu-Rayman, N. C. de Graauw, N. W. van de Donk, E. G. de Waal, M.-C. Vekemans, G. J. Timmers, M. van der Klift, S. Soechit, P. A. Geerts, M. H. Silbermann, M. Oosterveld, I. Nijhof, P. Sonneveld, S. K. Klein, M.-D. Levin, S. Zweegman

Publikováno v: HemaSphere, Vol 6, Pp 797-798 (2022)

Externí odkaz: https://doaj.org/article/de7b33949bb645c785d0c3c2f76a5ff0

Diffuse large B-cell lymphoma with MYC gene rearrangements: Current perspective on treatment of diffuse large B-cell lymphoma with MYC gene rearrangements; case series and review of the literature

Autor: A V, de Jonge, T J A, Roosma, I, Houtenbos, W L E, Vasmel, K, van de Hem, J P, de Boer, T, van Maanen, G, Lindauer-van der Werf, A, Beeker, G J, Timmers, C G, Schaar, M, Soesan, P J, Poddighe, D, de Jong, M E D, Chamuleau

Publikováno v: European journal of cancer (Oxford, England : 1990). 55

In the past decade, patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL) were treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) therapy. Standard treatment is now changing as a result of deeper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0bca61d5485338dd426694d46352da9
https://pubmed.ncbi.nlm.nih.gov/26820684

Amphotericin B colloidal dispersion (Amphocil) vs fluconazole for the prevention of fungal infections in neutropenic patients: Data of a prematurely stopped clinical trial

Autor: Daan J Touw, Sonja Zweegman, Peter C. Huijgens, G J Timmers, A M Simoons-Smit, A. C. Van Loenen

Publikováno v: Timmers, G J, Zweegman, S, Simoons-Smit, A M, Van Loenen, A C, Touw, D & Huijgens, P C 2000, ' Amphotericin B colloidal dispersion (Amphocil) vs fluconazole for the prevention of fungal infections in neutropenic patients: Data of a prematurely stopped clinical trial ', Bone Marrow Transplantation, vol. 25, no. 8, pp. 879-884 . https://doi.org/10.1038/sj.bmt.1702243
Bone marrow transplantation, 25(8), 879-84. Nature Publishing Group
Bone Marrow Transplantation, 25(8), 879-884. Nature Publishing Group

We conducted an open label, randomised clinical trial to compare amphotericin B colloidal dispersion (ABCD, Amphocil) 2 mg/kg/day intravenously with fluconazole 200 mg/day orally, for the prevention of fungal disease in neutropenic patients with haem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b8e41a84dca4e63e10abf97857c62f
https://doi.org/10.1038/sj.bmt.1702243

Pharmacokinetics and effects on bowel and throat microflora of oral levofloxacin as antibacterial prophylaxis in neutropenic patients with haematological malignancies

Autor: van Arie Winkelhoff, Christina M. J. E. Vandenbroucke-Grauls, Y Dijstelbloem, Daan J Touw, A M Simoons-Smit, Peter C. Huijgens, G J Timmers

Publikováno v: Timmers, G J, Dijstelbloem, Y, Simoons-Smit, A M, van Winkelhoff, A J, Touw, D J, Vandenbroucke-Grauls, C M J E & Huijgens, P C 2004, ' Pharmacokinetics and effects on bowel and throat microflora of oral levofloxacin as antibacterial prophylaxis in neutropenic patients with haematological malignancies. ', Bone Marrow Transplantation, vol. 33, no. 8, pp. 847-53 . https://doi.org/10.1038/sj.bmt.1704431
Timmers, G J, Dijstelbloem, Y, Simoons-Smit, A M, van Winkelhoff, A J, Touw, D, Vandenbroucke-Grauls, C M J E & Huijgens, P 2004, ' Pharmacokinetics and effects on bowel and throat microflora of oral levofloxacin as antibacterial prophylaxis in neutropenic patients with hematological malignancies ', Bone Marrow Transplantation, vol. 33, pp. 1-7 . https://doi.org/10.1038/sj.bmt.1704284
Bone Marrow Transplantation, 33, 1-7. Nature Publishing Group
Bone marrow transplantation, 33(8), 847-853. Nature Publishing Group
Bone Marrow Transplantation, 33(8), 847-53. Nature Publishing Group

Gram-positive breakthrough infections pose a major drawback to the use of quinolones for antibacterial prophylaxis in neutropenic patients. Levofloxacin offers the advantage of an augmented Gram-positive spectrum and may potentially overcome this pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105d048b3ffdfa697b929108e7582c25
https://research.vumc.nl/en/publications/7e9f9bc9-47cf-4b8e-93e5-bd4b4be0625c

[Hypertension in the Negro patient]

Autor: G J, Timmers, J A, Schouten, P M, ter Wee, R O, Gans

Publikováno v: Nederlands tijdschrift voor geneeskunde. 143(5)

Essential hypertension appears to be more prevalent among blacks than among whites and has an earlier onset in blacks. Many data in this field come from studies in the African-American population. Hypertension-related complications, e.g. ischaemic he

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73b80e9f3e0ec6b593c94561819b055f
https://pubmed.ncbi.nlm.nih.gov/10086150