Výsledky vyhledávání - "G J, Thomson"

Robotic Mammosphere Assay for High-Throughput Screening in Triple-Negative Breast Cancer

Autor: Göran Landberg, Paul A. Fitzpatrick, Elin M. V. Söderberg, Nina Akrap, G J Thomson, Hannah Harrison

Publikováno v: SLAS Discovery. 22:827-836

In order to identify novel treatment principles specifically affecting cancer stem cells in triple-negative breast cancer, we have developed a high-throughput screening method based on the mammosphere and anoikis resistance assays allowing us to scre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e6d3e92b68efb3a66f8f2cafc0129c
https://doi.org/10.1177/2472555217692321

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A functional role for a flexible loop containing Glu182 in the class II fructose-1,6-bisphosphate aldolase from Escherichia coli

Autor: S, Zgiby, A R, Plater, M A, Bates, G J, Thomson, A, Berry

Publikováno v: Journal of molecular biology. 315(2)

Class II fructose 1,6-bisphosphate aldolases (FBP-aldolases) catalyse the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP). Analysis of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ded0904404fd958a1a334bac1934400d
https://pubmed.ncbi.nlm.nih.gov/11779234

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Renal artery aneurysm: endovascular treatment by coil embolisation with preservation of renal blood flow

Autor: C D, Karkos, S P, D'Souza, G J, Thomson, A, Chomal, S S, Matanhelia

Publikováno v: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 19(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c130cb1f091a47032445837b1241a1f
https://pubmed.ncbi.nlm.nih.gov/10729110

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Exploring substrate binding and discrimination in fructose1, 6-bisphosphate and tagatose 1,6-bisphosphate aldolases

Autor: S M, Zgiby, G J, Thomson, S, Qamar, A, Berry

Publikováno v: European journal of biochemistry. 267(6)

Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. A recent structure of the Escherichia coli Class II fructose 1,6-bisphosphate aldolase [Hall, D.R.,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c2be26a4f5b18c1dedef29bc066def3
https://pubmed.ncbi.nlm.nih.gov/10712619

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Conserved residues in the mechanism of the E. coli Class II FBP-aldolase

Autor: A R, Plater, S M, Zgiby, G J, Thomson, S, Qamar, C W, Wharton, A, Berry

Publikováno v: Journal of molecular biology. 285(2)

The two classes of fructose-1,6-bisphosphate aldolase both catalyse the reversible cleavage of fructose 1,6-bisphosphate into dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. The Class I aldolases use Schiff base formation as part of their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71343db7e37454c05c419c419596eed7
https://pubmed.ncbi.nlm.nih.gov/9878448

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The response of rapidly formed adult human endothelial-cell monolayers to shear stress of flow: a comparison of fibronectin-coated Teflon and gelatin-impregnated Dacron grafts

Autor: R, Vohra, G J, Thomson, H M, Carr, H, Sharma, M G, Walker

Publikováno v: Surgery. 111(2)

Endothelial cells labeled with indium 111-oxine were seeded in supraconfluent densities onto fibronectin-coated expanded polytetrafluoroethylene (ePTFE) and gelatin-impregnated Dacron graft segments. These grafts with rapidly formed endothelial-cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bca473517db2ae25b130184044cc89c8
https://pubmed.ncbi.nlm.nih.gov/1531272

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A clinical trial of Gingkco Biloba Extract in patients with intermittent claudication

Autor: G J, Thomson, R K, Vohra, M H, Carr, M G, Walker

Publikováno v: International angiology : a journal of the International Union of Angiology. 9(2)

Thirty-seven patients with stage 2 peripheral vascular disease were randomised to receive a six month course of Gingkco Biloba Extract (Tanakan) or matching placebo. Assessment, by claudication distance, A/B ratio, Doppler ankle pressure response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c150bc92a8f985e55c528f7ab03e300a
https://pubmed.ncbi.nlm.nih.gov/2254678

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