Zobrazeno 1 - 10 of 65 pro vyhledávání: '"G J, Stanton"'
1
The interferons. Mechanisms of action and clinical applications
Autor: Gary R. Klimpel, Dorian H. Coppenhaver, G J Stanton, Stephen K. Tyring, Thomas K. Hughes, Fleischmann Wr, Samuel Baron, David W. Niesel
Publikováno v: JAMA: The Journal of the American Medical Association. 266:1375-1383
The interferons (IFN) are one of the body's natural defensive responses to such foreign components as microbes, tumors, and antigens. The IFN response begins with the production of the IFN proteins (α, β, and γ), which then induce the antiviral, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f489d3a91e852ec3346809afc11c9f85
https://doi.org/10.1001/jama.266.10.1375
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2
Modulation of Peripheral Leukocyte Counts in Mice by Oral Administration of Interferons
Autor: Jian-Ling Wang, Fleischmann Wr, E. E. Fields, Thomas K. Hughes, G J Stanton
Publikováno v: Experimental Biology and Medicine. 197:424-430
The ability of interferons (IFN) to exert a systemic effect following their oral administration was evaluated. One systemic effect of parenteral interferon administration has been shown to be a suppression of the number of peripheral white blood cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b0801ce4691902fdd2ce29cd9d8dd1
https://doi.org/10.3181/00379727-197-43277
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3
Production of interferon gamma messenger RNA by cells of non-immune origin
Autor: Samuel Baron, Patrick Cadet, Stephen K. Tyring, G J Stanton, Peter L. Rady, Thomas K. Hughes, T.K. Bui
Publikováno v: Cytokine. 7(8)
There is general agreement that IFN-gamma is produced only by cells of immune origin (T-cells, NK cells, and recently macrophages). However, indirect evidence has suggested that undetectable, low levels of IFN-gamma produced by cells of non-immune li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adc224a1bec9eeaab82303e8a55be42
https://pubmed.ncbi.nlm.nih.gov/8664446
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4
The Effects of Orally Applied and Systemic Interferon and Cytokines on Hormonal and Host Defense Mechanisms of Virus-Infected Mice
Autor: G. J. Stanton, T. K. Hughes
This report presents data that orally applied IFN can increase the levels of dehydroepiandrosterone (DHEA) sulfate in very young and old-age (20 months) mice and protect mice from Semliki Forest Virus infections. Large numbers of mice/group (42) were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d94ee7fa2bf9c259608c8cd395aea963
https://doi.org/10.21236/ada292762
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5
Prevention of resistance to IFN-alpha antiproliferative activity: characterization of the effect of IFN-gamma and substitution for IFN-gamma by tumor necrosis factor
Autor: C M, Fleischmann, G J, Stanton, W R, Fleischmann
Publikováno v: Journal of biological regulators and homeostatic agents. 7(2)
Non-genetic resistance to the antiproliferative effects of interferon-alpha (IFN-alpha) develops in murine and human melanoma cells within 2-4 days of exposure of the cells to IFN-alpha. Simultaneous treatment of murine B16 melanoma cells with MuIFN-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5593edfda8d8bd5d130de802e0180439
https://pubmed.ncbi.nlm.nih.gov/8266815
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6
Relative Ability of Mitogens to Stimulate Production of Interferon by Lymphoid Cells and to Induce Suppression of the in Vitro Immune Response
Autor: Samuel Baron, G J Stanton, Howard M. Johnson
Publikováno v: Experimental Biology and Medicine. 154:138-141
SummarySeveral T cell mitogens, con-canavalin A (Con A), phytohemagglutinin P (PHA-P), and staphylococcal enterotoxin A (SEA), were compared for their ability to inhibit the in vitro antibody response and to stimulate the production of mitogen (antig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d5aa0769cde38664666b73a6f7e033
https://doi.org/10.3181/00379727-154-39622
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7
Ocular herpes simplex virus infection is diminished by depletion of B lymphocytes
Autor: C Jordan, S Baron, F Dianzani, J Barber, G J Stanton
Publikováno v: The Journal of Immunology. 131:1554-1557
Rabbit anti-mouse mu-chain serum was used to deplete specifically IgM-bearing B cells and B cell function in BALB/c mice. B cell-depleted and normal littermates were infected via the cornea with herpes simplex virus type 1 (HSV-1) at 4 to 5 wk of age
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a42e0ae539b7f2a44d31d95834042b7b
https://doi.org/10.4049/jimmunol.131.3.1554
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8
Characterization of a soluble suppressor of human B cell function produced by a continuous human suppressor T cell line. II. Evidence for suppression through a direct action of CTC-SISS-B on human B cells
Autor: W C Greene, T A Fleisher, J M Depper, W J Leonard, G J Stanton, T A Waldmann
Publikováno v: The Journal of Immunology. 129:1120-1123
CTC-SISS-B is an antigen-nonspecific suppressive lymphokine elaborated by an interleukin 2-dependent suppressor T cell line that produces noncytotoxic inhibition of human B cell but not T cell function. Like SISS-B, a soluble suppressive lymphokine p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae61652d90604244caf2c07d306c31a9
https://doi.org/10.4049/jimmunol.129.3.1120
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10
Microassay for Sindbis virus and interferon activity
Autor: D A Weigent, R E Lloyd, G J Stanton
Publikováno v: Journal of Clinical Microbiology. 18:296-299
A simple and rapid microplaque assay for Sindbis virus was developed which uses microtiter plates and overlay medium consisting of methylcellulose and specific antibody to Sindbis virus. Discrete plaque formation was consistently observed on baby ham
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338a3ce9b7d0d0aa2343ced83b46c75c
https://doi.org/10.1128/jcm.18.2.296-299.1983
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