Zobrazeno 1 - 10
of 240
pro vyhledávání: '"G J, Smits"'
Autor:
G M R, DE Luca, E, Desclos, R M P, Breedijk, L, Dolz-Edo, G J, Smits, L, Nahidiazar, P, Bielefeld, L, Picavet, C P, Fitzsimons, R, Hoebe, E M M, Manders
Publikováno v:
Journal of microscopy. 266(2)
The new high-sensitive and high-resolution technique, Re-scan Confocal Microscopy (RCM), is based on a standard confocal microscope extended with a re-scan detection unit. The re-scan unit includes a pair of re-scanning mirrors that project the emiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1e87817aea0670304185465f860ef33
https://pubmed.ncbi.nlm.nih.gov/28257147
https://pubmed.ncbi.nlm.nih.gov/28257147
Publikováno v:
European Journal of Medicinal Chemistry. 25:589-594
Semi-peptidic analogues of the angiotensin II (AII) antagonist [Ile8] AII have been prepared by the solid phase method and, for some steps, by synthesis in solution. In the modified analogues 4–15, the N-terminal di- or tripeptidic fragments (Asp-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2677c62c224a1cf218e4597479b3ef0e
https://doi.org/10.1016/0223-5234(90)90183-4
https://doi.org/10.1016/0223-5234(90)90183-4
Autor:
Maria A. Palomo, Gillian M. Olins, G J Smits, K S Salles, Joan M. O'Neal, P R Bovy, Dennis R. Patton, A. J. Trapani, J P Koepke, Ellen G. Mcmahon
Publikováno v:
Journal of Medicinal Chemistry. 33:1477-1482
A series of analogues of the recently reported angiotensin II (AII) antagonist [Sar1]AII-(1-7)-amide or des-Phe8[Sar1]AII (3) have been prepared by solid-phase synthesis and purified by reverse-phase liquid chromatography. The agonist and antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1df0bc239548aec2e50ed2041de3888
https://doi.org/10.1021/jm00167a030
https://doi.org/10.1021/jm00167a030
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 286(2)
This study examined the cardioprotective effects and pharmacology of the novel adenosine A1/A2 receptor agonist ([1S-[1a,2b,3b, 4a(S*)]]-4-[7-[[2-(3-chloro-2-thienyl)-1-methylpropyl]amino]-3H-imida zo[4,5-b] pyridyl-3-yl] cyclopentane carboxamide) (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16d2395ba048bd720692807245935cf0
https://pubmed.ncbi.nlm.nih.gov/9694911
https://pubmed.ncbi.nlm.nih.gov/9694911
Autor:
Yue, Ouyang1,2 (AUTHOR), Wang, Xuechuan1,3 (AUTHOR) wangxc@sust.edu.cn, Xie, Long1,3 (AUTHOR), Bai, Zhongxue1,2 (AUTHOR), Zou, Xiaoliang1,2 (AUTHOR), Liu, Xinhua1,2 (AUTHOR) liuxinhua@sust.edu.cn
Publikováno v:
Advanced Science. 3/20/2024, Vol. 11 Issue 11, p1-42. 42p.
Publikováno v:
Yeast (Chichester, England). 12(5)
Glucose uptake in Saccharomyces cerevisiae is believed to consist of two kinetically distinguishable components, the affinity of which is modulated during growth on glucose. It has been reported that triple hexose-kinase deletion mutants do not exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b03783cc87ba55ca1e1ca75140c8ffa5
https://pubmed.ncbi.nlm.nih.gov/8740417
https://pubmed.ncbi.nlm.nih.gov/8740417
Autor:
G M, Olins, V M, Corpus, S T, Chen, E G, McMahon, M A, Palomo, D E, McGraw, G J, Smits, C L, Null, M A, Brown, S E, Bittner
Publikováno v:
Journal of cardiovascular pharmacology. 22(4)
We describe the pharmacologic properties of SC-52458, 5-[(3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(1H-tetrazol - 5-ylphenyl)]pyridine, a novel nonpeptide angiotensin II (AII) receptor antagonist. SC-52458 was a potent inhibitor of [125I]AII bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78e2c546208b61b640c1a4c508ef0293
https://pubmed.ncbi.nlm.nih.gov/7505365
https://pubmed.ncbi.nlm.nih.gov/7505365
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(1)
The present investigation was undertaken to define the hemodynamic mechanisms by which the selective cyclic GMP phosphodiesterase inhibitor zaprinast (MB 22,948; 2-o-propoxy-phenyl-8-azapurin-6-one) lowers mean arterial pressure (MAP). Anesthetized r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b2a84a2ca473d9fd7c1606bac7aa557
https://pubmed.ncbi.nlm.nih.gov/1649294
https://pubmed.ncbi.nlm.nih.gov/1649294
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 254(1)
An elevated plasma concentration of atrial natriuretic peptide (ANP) is characteristic of congestive heart failure (CHF) in both humans and animals. One strategy for facilitating the biological actions of this circulating hormone is to inhibit its me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fca29d5d6821f69a50928cf4f160ef43
https://pubmed.ncbi.nlm.nih.gov/2142219
https://pubmed.ncbi.nlm.nih.gov/2142219